iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069426

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01119830

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000001385.2	ENSNLET00000001763.2	ENSNLEP00000001666.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-71	238.9	25	457

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklnee.npkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsg 86
           Gl NlgNtC+mNS+LQ Ls++p + + l e ++++ +++ +++ +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s+
   Q: 25   GLVNLGNTCFMNSLLQGLSACPAFIRWLEE-FTSQYDRDqKEPPSHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISS 112
           9*****************************.55555544044567789999*********888899999******************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.s 164
           +e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + ++ +n+   ++ F+g+l+s+++c++c+++s +
   Q: 113  FEEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEitpkqitcrtRGSPHPISNHWKSQHPFHGRLTSNMVCKHCEHQSpV 199
           ********************9..6688888899988888888889999999999999999***************************** PP
   S: 165  reepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfs 238
           r+++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s
   Q: 200  RFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLS 285
           ************************************97...9******8888888888888777777********************** PP
   S: 239  fseeqksrekinkkvefpleLdlspfcts..................peekqke................................... 274
           +s++ + + k +++v+f++ L ++ +  +                  p     +                                   
   Q: 286  WSSH-GTPLKRHEHVQFNEFLMMDIYKYHllghkpsqpnpklnknpgP-----Tlelqdgpgaptpvlnqpgvpktqifmngacspsll 368
           *998.8888*********888887555555566766666555555550.....055555555555555555566666666666666666 PP
   S: 275  ....................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlf 334
                               ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lf
   Q: 369  ptlsapmpfplpvvpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsarnplsTSNQWLWVSDDTVRKASLQEVLS---SSAYLLF 454
           666666666666666666669999***********************9999988888999*******************...******* PP
   S: 335  Ykr 337
           Y+r
   Q: 455  YER 457
           *98 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGEKWVKCDM LFSSSPCFFL GLVPGLVNLG NTCFMNSLLQ GLSACPAFIR WLEEFTSQYD 60
RDQKEPPSHQ YLSLTLLHLL KALSCQEVTD DEVLDASCLL DVLRMYRWQI SSFEEQDAHE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTATTTT ACATTCTCCC TCCTTTTTGT GTGTCTTTGA GAACTTTGAT AATAAAAAGT 60
TTTTTAAAGA GATTGCTAGC AGAAGAGAGA AGTATATTAG ATTTTGTTAT CTCTGCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nle:100606082

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	28.86	3.00e-17	83.20
IUUC-Aml-001733	Ailuropoda melanoleuca	91.89	0.00e+00	797.00
IUUC-Atr-002510	Amborella trichopoda	24.95	5.00e-21	95.90
IUUC-Apl-003645	Anas platyrhynchos	71.48	3.00e-106	377.00
IUUC-Aca-004583	Anolis carolinensis	68.42	1.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	25.78	4.00e-22	99.40
IUUC-Ath-007622	Arabidopsis thaliana	26.54	1.00e-22	100.00
IUUC-Ame-010896	Astyanax mexicanus	61.43	2.00e-145	508.00
IUUC-Bta-012321	Bos taurus	90.29	0.00e+00	790.00
IUUC-Bdi-014795	Brachypodium distachyon	27.92	2.00e-18	87.00
IUUC-Bol-015637	Brassica oleracea	25.66	1.00e-22	100.00
IUUC-Bra-016801	Brassica rapa	24.90	5.00e-23	102.00
IUUC-Cel-018308	Caenorhabditis elegans	28.32	5.00e-38	152.00
IUUC-Cja-018826	Callithrix jacchus	97.36	0.00e+00	889.00
IUUC-Cfa-021206	Canis familiaris	91.89	0.00e+00	800.00
IUUC-Cpo-021343	Cavia porcellus	92.94	0.00e+00	806.00
IUUC-Csa-023419	Chlorocebus sabaeus	98.45	0.00e+00	895.00
IUUC-Cho-024475	Choloepus hoffmanni	89.09	6.00e-137	480.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	20.79	8.00e-12	65.90
IUUC-Cne-027061	Cryptococcus neoformans	26.10	6.00e-10	59.30
IUUC-Dre-027563	Danio rerio	58.92	2.00e-143	502.00
IUUC-Dno-029929	Dasypus novemcinctus	92.94	0.00e+00	818.00
IUUC-Dor-030166	Dipodomys ordii	80.57	0.00e+00	679.00
IUUC-Dme-031627	Drosophila melanogaster	35.29	6.00e-37	148.00
IUUC-Ete-032634	Echinops telfairi	80.35	0.00e+00	637.00
IUUC-Eca-033968	Equus caballus	93.38	0.00e+00	804.00
IUUC-Eeu-035279	Erinaceus europaeus	76.74	7.00e-48	184.00
IUUC-Fca-036525	Felis catus	92.94	0.00e+00	814.00
IUUC-Fal-036606	Ficedula albicollis	74.93	5.00e-152	530.00
IUUC-Gmo-038726	Gadus morhua	57.18	5.00e-132	464.00
IUUC-Gga-040718	Gallus gallus	74.59	4.00e-152	530.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.40	2.00e-135	476.00
IUUC-Gma-042890	Glycine max	25.97	2.00e-24	107.00
IUUC-Ggo-045021	Gorilla gorilla	99.12	0.00e+00	902.00
IUUC-Hsa-045832	Homo sapiens	99.12	0.00e+00	902.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	94.04	0.00e+00	820.00
IUUC-Lch-050662	Latimeria chalumnae	68.72	2.00e-167	581.00
IUUC-Lpe-051078	Leersia perrieri	26.76	1.00e-31	130.00
IUUC-Loc-052611	Lepisosteus oculatus	66.08	3.00e-165	574.00
IUUC-Lma-053048	Leptosphaeria maculans	20.44	2.00e-15	77.80
IUUC-Laf-053752	Loxodonta africana	91.61	0.00e+00	794.00
IUUC-Mcc-054892	Macaca mulatta	98.90	0.00e+00	899.00
IUUC-Meu-056673	Macropus eugenii	74.74	1.00e-162	565.00
IUUC-Mtr-057976	Medicago truncatula	26.85	2.00e-32	134.00
IUUC-Mla-058970	Melampsora laricipopulina	23.64	2.00e-20	94.00
IUUC-Mga-059543	Meleagris gallopavo	76.60	0.00e+00	668.00
IUUC-Mmr-061534	Microcebus murinus	94.26	0.00e+00	820.00
IUUC-Mdo-062140	Monodelphis domestica	67.83	8.00e-154	536.00
IUUC-Mmu-063673	Mus musculus	88.30	0.00e+00	773.00
IUUC-Mpu-066328	Mustela putorius furo	92.05	0.00e+00	806.00
IUUC-Mlu-067938	Myotis lucifugus	92.94	0.00e+00	806.00
IUUC-Opr-070796	Ochotona princeps	85.99	3.00e-124	438.00
IUUC-Ont-072248	Oreochromis niloticus	58.35	8.00e-140	490.00
IUUC-Oan-072916	Ornithorhynchus anatinus	80.13	0.00e+00	709.00
IUUC-Ocu-074459	Oryctolagus cuniculus	87.44	0.00e+00	661.00
IUUC-Oba-075765	Oryza barthii	27.54	7.00e-30	125.00
IUUC-Obr-076005	Oryza brachyantha	27.24	5.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	27.67	8.00e-34	138.00
IUUC-Ogu-078263	Oryza glumaepatula	27.54	1.00e-30	127.00
IUUC-Oin-080096	Oryza indica	27.85	5.00e-24	105.00
IUUC-Ome-081928	Oryza meridionalis	27.47	4.00e-32	132.00
IUUC-Oni-082424	Oryza nivara	27.54	2.00e-30	127.00
IUUC-Oru-085117	Oryza rufipogon	27.54	2.00e-30	127.00
IUUC-Ola-087429	Oryzias latipes	57.40	2.00e-132	465.00
IUUC-Oga-087981	Otolemur garnettii	93.82	0.00e+00	809.00
IUUC-Oar-089927	Ovis aries	89.85	0.00e+00	786.00
IUUC-Ptr-090878	Pan troglodytes	99.12	0.00e+00	902.00
IUUC-Pan-092698	Papio anubis	98.90	0.00e+00	899.00
IUUC-Psi-093451	Pelodiscus sinensis	76.97	0.00e+00	686.00
IUUC-Pno-094855	Phaeosphaeria nodorum	25.34	7.00e-10	58.20
IUUC-Pfo-096096	Poecilia formosa	57.74	8.00e-137	480.00
IUUC-Pab-098676	Pongo abelii	97.79	0.00e+00	882.00
IUUC-Pca-100418	Procavia capensis	96.00	2.00e-119	422.00
IUUC-Ppe-101898	Prunus persica	24.71	5.00e-25	108.00
IUUC-Pva-103018	Pteropus vampyrus	91.61	0.00e+00	791.00
IUUC-Pgr-103423	Puccinia graminis	24.74	3.00e-09	57.80
IUUC-Ptt-103779	Puccinia triticina	20.42	7.00e-12	66.20
IUUC-Pte-104330	Pyrenophora teres	22.16	2.00e-14	73.90
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.64	2.00e-16	80.90
IUUC-Rno-105708	Rattus norvegicus	87.20	0.00e+00	762.00
IUUC-Sha-106971	Sarcophilus harrisii	81.92	0.00e+00	731.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	24.02	2.00e-12	67.80
IUUC-Sit-110442	Setaria italica	26.60	7.00e-28	118.00
IUUC-Sly-110928	Solanum lycopersicum	23.73	2.00e-16	80.10
IUUC-Stu-112223	Solanum tuberosum	24.19	4.00e-17	82.40
IUUC-Ssc-116397	Sus scrofa	89.85	0.00e+00	786.00
IUUC-Tgu-117446	Taeniopygia guttata	70.63	6.00e-175	606.00
IUUC-Tru-118268	Takifugu rubripes	59.19	1.00e-129	456.00
IUUC-Tsy-119484	Tarsius syrichta	91.34	2.00e-52	199.00
IUUC-Tni-119735	Tetraodon nigroviridis	54.95	5.00e-116	410.00
IUUC-Tca-121660	Theobroma cacao	26.10	4.00e-27	116.00
IUUC-Tae-125203	Triticum aestivum	27.36	2.00e-28	120.00
IUUC-Tur-126458	Triticum urartu	27.00	2.00e-26	113.00
IUUC-Tbe-127740	Tupaia belangeri	86.75	0.00e+00	737.00
IUUC-Ttr-129273	Tursiops truncatus	89.18	0.00e+00	779.00
IUUC-Vda-129789	Verticillium dahliae	22.84	5.00e-08	53.10
IUUC-Vvi-131177	Vitis vinifera	25.90	4.00e-28	119.00
IUUC-Xtr-132374	Xenopus tropicalis	66.52	4.00e-162	564.00
IUUC-Xma-133267	Xiphophorus maculatus	60.71	4.00e-141	494.00
IUUC-Yli-134571	Yarrowia lipolytica	23.82	2.00e-12	67.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence