iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089927

Ensembl Protein ID

ENSOARP00000018293.1

UniProt Accession

W5Q6F3; W5Q6F3_SHEEP

Genbank Protein ID

ENSOARP00000018293

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01039637

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000017038.1	ENSOART00000018554.1	ENSOARP00000018293.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.50e-70	236.1	69	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +   +++ +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPTFIKWLEEFTTQYTGSHKEPPQHQYLSLTLLHLLKALScqeVTDEEVLDASCLLDVLRMYRWQISSF 157
           9*****************************66666666666788899************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + ++ +n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQTEitprqitcrtRGSPHPASNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           *******************9..6688888999998888888889999999999999********************************* PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 245  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts............................................................. 267
           s++ + + k +++v+f + L ++ +  +                                                             
   Q: 331  SSQ-GTPLKRHEHVQFGEFLMMDIYKYHllghkpghrgpercekagpalelqdgpaapksvrnhpggpktqifmngacspsllpalptp 418
           996.8889*********888888666666678888888877777777777777777766666666666666666665555555555555 PP
   S: 268  ........peekqke....kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                   p     +    ++ ++L+avvvH+G ++sGH+v+y ++          + +Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 419  mpfplpavP-----DysssTYLFQLMAVVVHHGDMHSGHFVTYRRSppsaknpvsASSQWLWVSDDTVRKASLQEVLS---SSAYLLFY 499
           555555553.....055449999***********************8888887777888*******************...******** PP
   S: 336  kr 337
           +r
   Q: 500  ER 501
           98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLSSRASAAM TAADRAIQRF LRTGAAVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP TFIKWLEEFT TQYTGSHKEP PQHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAGCT CCCGGGCCTC GGCGGCGATG ACCGCGGCCG ACAGGGCCAT CCAGCGCTTC 60
CTGCGGACCG GGGCCGCCGT CAGGTGAGCT CTGGGGGGCG GGGCGGCCGG GGAGGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

oas:101123665

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	29.19	6.00e-15	75.50
IUUC-Aml-001733	Ailuropoda melanoleuca	91.35	0.00e+00	853.00
IUUC-Atr-002510	Amborella trichopoda	24.85	7.00e-23	102.00
IUUC-Apl-003645	Anas platyrhynchos	72.04	3.00e-106	377.00
IUUC-Aca-004583	Anolis carolinensis	65.79	2.00e-23	100.00
IUUC-Aly-005754	Arabidopsis lyrata	24.79	3.00e-24	106.00
IUUC-Ath-007622	Arabidopsis thaliana	25.87	7.00e-23	102.00
IUUC-Ame-010896	Astyanax mexicanus	61.89	6.00e-154	537.00
IUUC-Bta-012321	Bos taurus	98.45	0.00e+00	922.00
IUUC-Bci-013641	Botrytis cinerea	23.11	5.00e-11	62.80
IUUC-Bdi-014795	Brachypodium distachyon	29.26	1.00e-17	84.30
IUUC-Bol-015637	Brassica oleracea	26.14	7.00e-23	101.00
IUUC-Bra-016801	Brassica rapa	26.35	9.00e-24	104.00
IUUC-Cel-018308	Caenorhabditis elegans	28.17	1.00e-37	150.00
IUUC-Cja-018826	Callithrix jacchus	91.31	0.00e+00	900.00
IUUC-Cfa-021206	Canis familiaris	89.42	0.00e+00	858.00
IUUC-Cpo-021343	Cavia porcellus	89.82	0.00e+00	829.00
IUUC-Csa-023419	Chlorocebus sabaeus	90.91	0.00e+00	896.00
IUUC-Cho-024475	Choloepus hoffmanni	88.73	9.00e-137	479.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	22.71	4.00e-12	66.60
IUUC-Cne-027061	Cryptococcus neoformans	25.10	7.00e-10	59.30
IUUC-Dre-027563	Danio rerio	57.66	2.00e-156	545.00
IUUC-Dno-029929	Dasypus novemcinctus	89.56	0.00e+00	874.00
IUUC-Dor-030166	Dipodomys ordii	80.46	0.00e+00	720.00
IUUC-Dse-031517	Dothistroma septosporum	23.17	8.00e-11	62.40
IUUC-Dme-031627	Drosophila melanogaster	33.91	3.00e-34	139.00
IUUC-Ete-032634	Echinops telfairi	78.72	0.00e+00	687.00
IUUC-Eca-033968	Equus caballus	91.22	0.00e+00	824.00
IUUC-Eeu-035279	Erinaceus europaeus	82.32	1.00e-58	220.00
IUUC-Fca-036525	Felis catus	92.26	0.00e+00	886.00
IUUC-Fal-036606	Ficedula albicollis	74.22	9.00e-160	556.00
IUUC-Gmo-038726	Gadus morhua	56.19	2.00e-144	505.00
IUUC-Gga-040718	Gallus gallus	74.81	1.00e-161	562.00
IUUC-Gac-042645	Gasterosteus aculeatus	58.27	3.00e-151	528.00
IUUC-Gma-042890	Glycine max	25.66	3.00e-24	106.00
IUUC-Ggo-045021	Gorilla gorilla	90.91	0.00e+00	894.00
IUUC-Hsa-045832	Homo sapiens	90.91	0.00e+00	894.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	91.63	0.00e+00	832.00
IUUC-Lch-050662	Latimeria chalumnae	70.13	4.00e-179	620.00
IUUC-Lpe-051078	Leersia perrieri	26.19	6.00e-31	128.00
IUUC-Loc-052611	Lepisosteus oculatus	65.69	1.00e-177	615.00
IUUC-Lma-053048	Leptosphaeria maculans	19.88	1.00e-14	75.50
IUUC-Laf-053752	Loxodonta africana	91.22	0.00e+00	823.00
IUUC-Mcc-054892	Macaca mulatta	91.30	0.00e+00	899.00
IUUC-Meu-056673	Macropus eugenii	73.63	3.00e-160	558.00
IUUC-Mtr-057976	Medicago truncatula	27.27	7.00e-33	135.00
IUUC-Mla-058970	Melampsora laricipopulina	21.84	2.00e-20	94.00
IUUC-Mga-059543	Meleagris gallopavo	75.38	0.00e+00	660.00
IUUC-Mmr-061534	Microcebus murinus	91.68	0.00e+00	870.00
IUUC-Mdo-062140	Monodelphis domestica	67.98	7.00e-164	570.00
IUUC-Mmu-063673	Mus musculus	87.62	0.00e+00	819.00
IUUC-Mpu-066328	Mustela putorius furo	90.72	0.00e+00	842.00
IUUC-Mlu-067938	Myotis lucifugus	91.88	0.00e+00	899.00
IUUC-Nle-069426	Nomascus leucogenys	89.59	0.00e+00	799.00
IUUC-Opr-070796	Ochotona princeps	84.05	3.00e-120	425.00
IUUC-Ont-072248	Oreochromis niloticus	61.13	1.00e-157	549.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.34	0.00e+00	761.00
IUUC-Ocu-074459	Oryctolagus cuniculus	85.13	0.00e+00	650.00
IUUC-Oba-075765	Oryza barthii	26.82	2.00e-29	124.00
IUUC-Obr-076005	Oryza brachyantha	26.76	6.00e-30	125.00
IUUC-Ogl-077916	Oryza glaberrima	26.58	3.00e-32	133.00
IUUC-Ogu-078263	Oryza glumaepatula	27.19	3.00e-30	126.00
IUUC-Oin-080096	Oryza indica	26.64	2.00e-23	103.00
IUUC-Ome-081928	Oryza meridionalis	26.59	2.00e-30	127.00
IUUC-Oni-082424	Oryza nivara	27.19	3.00e-30	126.00
IUUC-Oru-085117	Oryza rufipogon	27.19	3.00e-30	126.00
IUUC-Ola-087429	Oryzias latipes	57.51	7.00e-149	520.00
IUUC-Oga-087981	Otolemur garnettii	90.91	0.00e+00	859.00
IUUC-Ptr-090878	Pan troglodytes	90.91	0.00e+00	894.00
IUUC-Pan-092698	Papio anubis	91.30	0.00e+00	899.00
IUUC-Psi-093451	Pelodiscus sinensis	75.51	0.00e+00	705.00
IUUC-Ppa-096015	Physcomitrella patens	25.53	1.00e-09	58.90
IUUC-Pfo-096096	Poecilia formosa	58.75	2.00e-155	541.00
IUUC-Pab-098676	Pongo abelii	89.75	0.00e+00	874.00
IUUC-Pca-100418	Procavia capensis	94.64	1.00e-128	452.00
IUUC-Ppe-101898	Prunus persica	24.71	4.00e-25	109.00
IUUC-Pva-103018	Pteropus vampyrus	89.75	0.00e+00	856.00
IUUC-Pgr-103423	Puccinia graminis	26.36	1.00e-09	58.90
IUUC-Ptt-103779	Puccinia triticina	22.25	3.00e-13	70.90
IUUC-Pte-104330	Pyrenophora teres	21.57	3.00e-14	73.90
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.02	6.00e-18	86.30
IUUC-Rno-105708	Rattus norvegicus	87.62	0.00e+00	817.00
IUUC-Sha-106971	Sarcophilus harrisii	78.16	0.00e+00	762.00
IUUC-Sit-110442	Setaria italica	26.57	2.00e-27	117.00
IUUC-Ssc-116397	Sus scrofa	93.81	0.00e+00	882.00
IUUC-Tgu-117446	Taeniopygia guttata	68.87	0.00e+00	634.00
IUUC-Tru-118268	Takifugu rubripes	58.72	1.00e-142	499.00
IUUC-Tsy-119484	Tarsius syrichta	86.51	5.00e-49	188.00
IUUC-Tni-119735	Tetraodon nigroviridis	53.16	5.00e-119	421.00
IUUC-Tca-121660	Theobroma cacao	25.19	3.00e-29	123.00
IUUC-Tae-125383	Triticum aestivum	27.98	1.00e-27	117.00
IUUC-Tur-126458	Triticum urartu	27.73	7.00e-26	111.00
IUUC-Tbe-127740	Tupaia belangeri	85.11	0.00e+00	774.00
IUUC-Ttr-129273	Tursiops truncatus	91.68	0.00e+00	852.00
IUUC-Vda-129757	Verticillium dahliae	21.57	6.00e-10	59.30
IUUC-Vvi-131177	Vitis vinifera	25.53	3.00e-26	112.00
IUUC-Xtr-132374	Xenopus tropicalis	66.67	1.00e-170	592.00
IUUC-Xma-133267	Xiphophorus maculatus	60.48	6.00e-158	550.00
IUUC-Zma-135796	Zea mays	26.48	2.00e-24	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence