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Tag Content
UUCD2 ID IUUC-Oga-088604
UUCD1 version UUC-OtG-00482
Ensembl Protein ID ENSOGAP00000010724.2
UniProt Accession H0X5X3; H0X5X3_OTOGA
Genbank Protein ID ENSOGAP00000010724
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03006620
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000011988.2 ENSOGAT00000011991.2 ENSOGAP00000010724.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.60e-55 181.4 479 513
UBD/Beta-Prp 1.00e-68 231.7 392 557
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 479  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 513
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 392  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 475
           4555679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 476  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 557
           ***************9..***********************************99.************..99**************7 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
SPQPLWVVCI CFSASVIRAS CVTGRETCSM TILLNTSVME DQNEDESPKK NTLWQFYSQC 60
LRVCFHLFVF CFSSGSEDIG HIVSFEKISN GTSSVIVSRK RPSEGNYQKE KDLCIKYFDQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088604|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCCCACAAC CACTCTGGGT GGTTTGTATT TGTTTCAGCG CTAAAATAAC TTGCTCCAGG 60
TTACATACGT ACACACAGTA AGTGAGTGAC CAAATCAGGA ATCAAAATTC TGTCTTTAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088604|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 99.80 0.00e+00 1020.00
IUUC-Apl-003449 Anas platyrhynchos 89.66 0.00e+00 1045.00
IUUC-Ago-007794 Ashbya gossypii 29.04 6.00e-48 185.00
IUUC-Ang-009766 Aspergillus niger 31.41 6.00e-52 198.00
IUUC-Ame-011393 Astyanax mexicanus 85.04 0.00e+00 948.00
IUUC-Bta-012920 Bos taurus 93.62 0.00e+00 1047.00
IUUC-Cja-018879 Callithrix jacchus 99.80 0.00e+00 1020.00
IUUC-Cfa-020021 Canis familiaris 99.80 0.00e+00 1020.00
IUUC-Cpo-022151 Cavia porcellus 93.77 0.00e+00 1038.00
IUUC-Csa-024095 Chlorocebus sabaeus 94.10 0.00e+00 1039.00
IUUC-Cho-024658 Choloepus hoffmanni 99.07 5.00e-126 444.00
IUUC-Dre-028160 Danio rerio 85.37 0.00e+00 954.00
IUUC-Dor-030498 Dipodomys ordii 99.39 0.00e+00 1013.00
IUUC-Dse-031287 Dothistroma septosporum 29.14 2.00e-52 200.00
IUUC-Eca-033804 Equus caballus 99.80 0.00e+00 1019.00
IUUC-Fca-035887 Felis catus 93.98 0.00e+00 1050.00
IUUC-Fal-036783 Ficedula albicollis 93.12 0.00e+00 1043.00
IUUC-Gmo-038590 Gadus morhua 90.54 0.00e+00 926.00
IUUC-Gga-040628 Gallus gallus 92.75 0.00e+00 1038.00
IUUC-Gac-041305 Gasterosteus aculeatus 90.14 0.00e+00 929.00
IUUC-Ggo-044604 Gorilla gorilla 99.80 0.00e+00 1020.00
IUUC-Hsa-046139 Homo sapiens 99.80 0.00e+00 1020.00
IUUC-Lch-050460 Latimeria chalumnae 90.89 0.00e+00 1019.00
IUUC-Laf-053968 Loxodonta africana 90.33 0.00e+00 1056.00
IUUC-Mcc-055822 Macaca mulatta 90.16 0.00e+00 1055.00
IUUC-Mga-059225 Meleagris gallopavo 93.24 0.00e+00 1031.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 256.00
IUUC-Mmr-060746 Microcebus murinus 99.80 0.00e+00 1020.00
IUUC-Mdo-062005 Monodelphis domestica 93.54 0.00e+00 1034.00
IUUC-Mmu-063851 Mus musculus 89.64 0.00e+00 1050.00
IUUC-Mpu-065716 Mustela putorius furo 93.43 0.00e+00 1045.00
IUUC-Mlu-067001 Myotis lucifugus 94.10 0.00e+00 1039.00
IUUC-Nle-069788 Nomascus leucogenys 100.00 0.00e+00 1019.00
IUUC-Opr-071229 Ochotona princeps 99.60 0.00e+00 1018.00
IUUC-Ont-071792 Oreochromis niloticus 90.74 0.00e+00 937.00
IUUC-Oan-072782 Ornithorhynchus anatinus 93.12 0.00e+00 1043.00
IUUC-Ocu-074894 Oryctolagus cuniculus 90.33 0.00e+00 1056.00
IUUC-Ola-086985 Oryzias latipes 81.24 0.00e+00 949.00
IUUC-Oar-090412 Ovis aries 93.48 0.00e+00 1047.00
IUUC-Ptr-091039 Pan troglodytes 99.60 0.00e+00 1018.00
IUUC-Pan-092770 Papio anubis 89.95 0.00e+00 1007.00
IUUC-Psi-093887 Pelodiscus sinensis 89.12 0.00e+00 1040.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 1.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 81.48 0.00e+00 949.00
IUUC-Pva-102547 Pteropus vampyrus 99.60 0.00e+00 1013.00
IUUC-Rno-105246 Rattus norvegicus 92.75 0.00e+00 1041.00
IUUC-Sce-106343 Saccharomyces cerevisiae 30.09 4.00e-46 179.00
IUUC-Sha-107339 Sarcophilus harrisii 93.54 0.00e+00 1034.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 5.00e-74 271.00
IUUC-Spo-108200 Schizosaccharomyces pombe 31.92 2.00e-66 246.00
IUUC-Tgu-116541 Taeniopygia guttata 89.64 0.00e+00 1045.00
IUUC-Tru-117671 Takifugu rubripes 80.72 0.00e+00 940.00
IUUC-Tni-120359 Tetraodon nigroviridis 84.73 0.00e+00 937.00
IUUC-Tbe-127418 Tupaia belangeri 93.12 0.00e+00 933.00
IUUC-Ttr-129131 Tursiops truncatus 99.80 0.00e+00 1019.00
IUUC-Vpa-130668 Vicugna pacos 99.80 0.00e+00 1018.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 1.00e-157 548.00
Created Date 25-Jun-2017

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