iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117807

UUCD1 version

UUC-TaR-01161

Ensembl Protein ID

ENSTRUP00000032813.1

UniProt Accession

H2U797; H2U797_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012940.1	ENSTRUT00000032937.1	ENSTRUP00000032812.1
ENSTRUG00000012940.1	ENSTRUT00000032938.1	ENSTRUP00000032813.1
ENSTRUG00000012940.1	ENSTRUT00000032939.1	ENSTRUP00000032814.1
ENSTRUG00000012940.1	ENSTRUT00000032940.1	ENSTRUP00000032815.1
ENSTRUG00000012940.1	ENSTRUT00000032941.1	ENSTRUP00000032816.1
ENSTRUG00000012940.1	ENSTRUT00000032942.1	ENSTRUP00000032817.1
ENSTRUG00000012940.1	ENSTRUT00000032943.1	ENSTRUP00000032818.1
ENSTRUG00000012940.1	ENSTRUT00000032944.1	ENSTRUP00000032819.1
ENSTRUG00000012940.1	ENSTRUT00000032945.1	ENSTRUP00000032820.1
ENSTRUG00000012940.1	ENSTRUT00000032946.1	ENSTRUP00000032821.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-56	192.1	147	626

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +G++N+gNtC++ +v+Q+L+++p +r+l+l+     +  ek++  + ++++ +++++l+ lf+ ++ s+++ v+p++ ++ l+++ +  
   Q: 147  VGIRNVGNTCWFSAVIQSLFHLPVFRRLVLNyrlseRILEKCKSHS-DKRNIAFMQELRCLFALMVGSTRRFVDPSAAVELLRDAFRT- 233
           6*******************************99887788887664.79999*******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            + +qqD++Ef + lld le++++                     + ++   k+++++++lF g++ ++ k    +++    e+f +++
   Q: 234  -SEAQQDVSEFSHKLLDWLEDAFQL-------A-----------ANGSDAADKQQNPMVQLFYGTFVTERKID--GKTLCNIEQFGQYP 301
           .89********************22.......2...........24456889999************887774..5555779******* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l +cLe  + e+e+e+   +++   +++  + ++ ++kklP+vL+++L+Rf+f+ + +++eki+kk+efp  + ++
   Q: 302  LQVNGFN-----NLYECLEGAMVEKEIES---LHS---DHSIPSGRERWFKKLPPVLTFELSRFEFNTQLGRPEKIHKKLEFPPIIHMD 379
           *******.....9***********99995...444...556678999****************************************** PP
   S: 263  pfcts.....peekqke........................................................................ 274
           +++++           e                                                                        
   Q: 380  RYLHKnieqmH-----Errrdvkklkdqlaalqqelecyrnygsgptkypladmlqfvlefattkpinltaaedprpsspspsqpgqpv 463
           *****555550.....4455555555555555555555555555555555555555555555555566666666666666666666666 PP
   S: 275  ......................................................................................... 274
                                                                                                    
   Q: 464  geatsqdtrdteppeglvsscqrtpiykpftqcrppiecpphpaphsitdeelhfvktclqrwraevendinelkanidrlsqmlesmy 552
           66666667777777777777777777788888888888888888888888888888888888888888888889999999999999999 PP
   S: 275  ......kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                 ++ Y+L+av+vH+G++s GHY+ay++++ ++ W++++D +++e+++ee ++++      ++aY+l+Y 
   Q: 553  sdnrlcQVPYRLHAVLVHEGQASAGHYWAYIYDHANQrWMKYNDINISESSWEELERDSFggmtnASAYCLMYI 626
           999999***************************88888*******************87799***********6 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TTAEPYESDV CHQGDLVINQ LREITGIQDP QVLHSALNAS QGDVGLAVGL LTSQPPEVQD 60
PGDPQESKTS DETWESQKGL PEDELQTAIE LSLQESHNAQ QEEKDLNRVL EASAEENLAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGCGTCGA AAATGAAAGA AAAGGGCGAA CATGGACAAA AGGCGGCGGC CACGGTGAGC 60
GCAAAGCATC CTGGGAGCGA TATTAATATC GATAACTAAC ACGGACGTGT GAGAAACTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0000077--P:DNA damage checkpoint
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	54.58	0.00e+00	1134.00
IUUC-Apl-004010	Anas platyrhynchos	52.07	0.00e+00	1068.00
IUUC-Aca-004741	Anolis carolinensis	50.57	0.00e+00	674.00
IUUC-Ang-009577	Aspergillus niger	32.32	2.00e-10	62.40
IUUC-Ate-010275	Aspergillus terreus	31.03	1.00e-11	65.90
IUUC-Bgr-011993	Blumeria graminis	37.84	3.00e-12	67.80
IUUC-Bta-013377	Bos taurus	53.63	0.00e+00	1095.00
IUUC-Cel-018346	Caenorhabditis elegans	27.52	3.00e-27	117.00
IUUC-Cja-019977	Callithrix jacchus	54.94	0.00e+00	1104.00
IUUC-Csv-025911	Ciona savignyi	34.66	5.00e-143	501.00
IUUC-Cme-027167	Cyanidioschyzon merolae	34.56	2.00e-17	85.10
IUUC-Dre-028105	Danio rerio	72.85	0.00e+00	966.00
IUUC-Dor-030955	Dipodomys ordii	53.34	0.00e+00	1064.00
IUUC-Ete-032828	Echinops telfairi	49.61	0.00e+00	690.00
IUUC-Eca-034300	Equus caballus	53.85	0.00e+00	1080.00
IUUC-Eeu-034458	Erinaceus europaeus	52.74	0.00e+00	957.00
IUUC-Fca-035753	Felis catus	54.85	0.00e+00	1130.00
IUUC-Gmo-039593	Gadus morhua	68.87	0.00e+00	1418.00
IUUC-Gga-040878	Gallus gallus	50.93	0.00e+00	1004.00
IUUC-Gac-041867	Gasterosteus aculeatus	76.14	0.00e+00	1630.00
IUUC-Ggo-045384	Gorilla gorilla	54.66	0.00e+00	1103.00
IUUC-Hsa-046277	Homo sapiens	54.71	0.00e+00	1106.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	47.31	3.00e-174	605.00
IUUC-Lch-049692	Latimeria chalumnae	57.22	0.00e+00	1190.00
IUUC-Laf-053808	Loxodonta africana	51.53	0.00e+00	1040.00
IUUC-Meu-056416	Macropus eugenii	46.35	0.00e+00	872.00
IUUC-Mga-060011	Meleagris gallopavo	52.61	0.00e+00	1068.00
IUUC-Mmr-060720	Microcebus murinus	52.88	0.00e+00	1054.00
IUUC-Mdo-061955	Monodelphis domestica	50.09	0.00e+00	985.00
IUUC-Mmu-063870	Mus musculus	52.52	0.00e+00	1046.00
IUUC-Mlu-067487	Myotis lucifugus	52.75	0.00e+00	1075.00
IUUC-Nle-070044	Nomascus leucogenys	53.88	0.00e+00	1102.00
IUUC-Opr-070888	Ochotona princeps	57.55	7.00e-93	335.00
IUUC-Ont-072386	Oreochromis niloticus	80.60	0.00e+00	1163.00
IUUC-Ocu-074523	Oryctolagus cuniculus	52.84	0.00e+00	1079.00
IUUC-Ola-086393	Oryzias latipes	73.79	0.00e+00	1569.00
IUUC-Psi-093422	Pelodiscus sinensis	53.32	0.00e+00	714.00
IUUC-Pma-094250	Petromyzon marinus	44.11	1.00e-58	219.00
IUUC-Pno-095093	Phaeosphaeria nodorum	32.71	4.00e-13	70.50
IUUC-Pfo-096466	Poecilia formosa	80.97	0.00e+00	1157.00
IUUC-Pab-098337	Pongo abelii	54.80	0.00e+00	1100.00
IUUC-Pva-102226	Pteropus vampyrus	52.57	0.00e+00	983.00
IUUC-Sha-107489	Sarcophilus harrisii	54.69	0.00e+00	1127.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	31.48	5.00e-10	60.50
IUUC-Sre-115145	Sporisorium reilianum	22.11	3.00e-10	62.00
IUUC-Tgu-116609	Taeniopygia guttata	53.45	0.00e+00	1048.00
IUUC-Tni-119983	Tetraodon nigroviridis	84.76	0.00e+00	1824.00
IUUC-Ttr-128887	Tursiops truncatus	49.95	0.00e+00	1004.00
IUUC-Uma-129338	Ustilago maydis	23.18	1.00e-12	69.70
IUUC-Xtr-132436	Xenopus tropicalis	51.92	0.00e+00	1042.00
IUUC-Xma-133995	Xiphophorus maculatus	81.22	0.00e+00	1115.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence