iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027380

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 14

Genbank Nucleotide ID

CU459117

Gene Name

rnf14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000043905.5	ENSDART00000010942.7	ENSDARP00000017558.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.70e-45	155.3	204	417

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C +C++e+   +++ + eCeh++Ck+C+k+y++++ik+g+v++++cp+++c ++++++++k  lv e+ ++ry++lll+++++ +a++ +
   Q: 204  CGICYSEKLGCDCLLFKECEHVYCKACIKEYFQIQIKDGKVQCLNCPEPKCASTATPTQVKL-LVGEDEFARYDRLLLQSSLDLMADVVY 292
           99***********************************************************9.79999********************** PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeskel 156
           cp+ +C ++v++e++  ++   c++c+ +fC+ C++++H  ++C +++++l++ ++e+                        ee+ s+ +
   Q: 293  CPRMSCCMAVMVEPD--STMGICPSCRYAFCTLCRRSYHGLSHCIATADELRSLRDEYlssseegkkflekrfgkrviqravEESFSTDW 380
           **************5..555559********************************999******************************** PP
   S: 157  leanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           l++n k+Cp+C + i+k  gCn+mtC++C+++fCw+C
   Q: 381  LKTNCKQCPCCGTNIQKAHGCNKMTCSSCQKYFCWIC 417
           ************************************* PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSADQEAKED ELLALASIYD EEEFHRAESG KEGEIHLCLE LPPNFKLLVK GQKSAEHNIS 60
FLPPLVLSFD LPDDYPSTSA PIFTISSKWL TRVQITALCR KLDELWEENQ GNVVLFTWIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAGAAC CCGATGACGA CGAAGAAGAA GTCAAACACA AGAGCTCCTC CTATCAGGCC 60
TGTAGTGAGA TTGCTGTTTT GCGTGGGGTT GCTTTGGCCA GAGTAAGGTA CGTGATTTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060828--P:regulation of canonical Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	33.19	9.00e-64	238.00
IUUC-Aml-001458	Ailuropoda melanoleuca	57.08	1.00e-150	526.00
IUUC-Atr-002560	Amborella trichopoda	29.74	3.00e-53	203.00
IUUC-Apl-003680	Anas platyrhynchos	58.90	2.00e-163	568.00
IUUC-Aca-005000	Anolis carolinensis	57.48	3.00e-153	535.00
IUUC-Aly-006288	Arabidopsis lyrata	29.37	1.00e-54	208.00
IUUC-Ath-006719	Arabidopsis thaliana	29.73	3.00e-56	213.00
IUUC-Acl-008213	Aspergillus clavatus	25.39	2.00e-37	150.00
IUUC-Afl-008433	Aspergillus flavus	24.66	2.00e-38	154.00
IUUC-Afu-008772	Aspergillus fumigatus	26.29	7.00e-42	165.00
IUUC-Ani-009249	Aspergillus nidulans	24.18	6.00e-35	142.00
IUUC-Ang-009757	Aspergillus niger	27.14	4.00e-41	162.00
IUUC-Aor-009963	Aspergillus oryzae	24.66	4.00e-38	153.00
IUUC-Ate-010460	Aspergillus terreus	24.24	1.00e-36	147.00
IUUC-Ame-011312	Astyanax mexicanus	71.65	0.00e+00	672.00
IUUC-Bgr-012052	Blumeria graminis	23.87	8.00e-34	138.00
IUUC-Bta-013529	Bos taurus	56.90	4.00e-153	534.00
IUUC-Bci-013729	Botrytis cinerea	24.77	5.00e-35	142.00
IUUC-Bdi-014940	Brachypodium distachyon	31.26	3.00e-57	216.00
IUUC-Bra-016998	Brassica rapa	31.38	4.00e-55	209.00
IUUC-Cel-018547	Caenorhabditis elegans	28.98	4.00e-54	205.00
IUUC-Cja-019791	Callithrix jacchus	56.47	2.00e-152	532.00
IUUC-Cfa-020403	Canis familiaris	57.33	2.00e-154	538.00
IUUC-Cpo-022229	Cavia porcellus	56.53	2.00e-146	512.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	34.26	1.00e-29	122.00
IUUC-Csa-024115	Chlorocebus sabaeus	56.47	1.00e-152	533.00
IUUC-Cho-024911	Choloepus hoffmanni	56.68	8.00e-153	533.00
IUUC-Cin-025578	Ciona intestinalis	43.38	7.00e-104	370.00
IUUC-Csv-026355	Ciona savignyi	40.29	5.00e-87	314.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	23.62	6.00e-36	145.00
IUUC-Cne-026782	Cryptococcus neoformans	25.78	6.00e-38	152.00
IUUC-Dno-029640	Dasypus novemcinctus	56.99	4.00e-153	534.00
IUUC-Dor-030681	Dipodomys ordii	56.90	3.00e-153	535.00
IUUC-Dse-031208	Dothistroma septosporum	23.11	3.00e-32	133.00
IUUC-Ete-033122	Echinops telfairi	46.81	2.00e-106	379.00
IUUC-Eca-033755	Equus caballus	56.68	1.00e-151	529.00
IUUC-Eeu-035034	Erinaceus europaeus	58.56	8.00e-39	154.00
IUUC-Fca-036461	Felis catus	57.51	1.00e-152	533.00
IUUC-Fal-037516	Ficedula albicollis	57.93	9.00e-166	576.00
IUUC-Fso-038307	Fusarium solani	24.94	2.00e-36	147.00
IUUC-Gmo-039563	Gadus morhua	68.37	0.00e+00	644.00
IUUC-Ggr-039920	Gaeumannomyces graminis	23.23	2.00e-29	124.00
IUUC-Gga-040331	Gallus gallus	57.23	2.00e-160	558.00
IUUC-Gac-042164	Gasterosteus aculeatus	67.09	0.00e+00	662.00
IUUC-Gma-044080	Glycine max	30.73	4.00e-59	223.00
IUUC-Ggo-045257	Gorilla gorilla	56.47	2.00e-152	532.00
IUUC-Hsa-046887	Homo sapiens	57.21	1.00e-151	529.00
IUUC-Hvu-047317	Hordeum vulgare	30.65	4.00e-55	209.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	57.11	4.00e-154	538.00
IUUC-Lch-050155	Latimeria chalumnae	57.52	2.00e-155	542.00
IUUC-Lpe-051669	Leersia perrieri	30.09	1.00e-38	154.00
IUUC-Loc-051779	Lepisosteus oculatus	65.20	8.00e-174	603.00
IUUC-Lma-052969	Leptosphaeria maculans	25.00	2.00e-36	146.00
IUUC-Laf-053488	Loxodonta africana	57.26	7.00e-159	553.00
IUUC-Mcc-054701	Macaca mulatta	56.99	2.00e-151	528.00
IUUC-Meu-056577	Macropus eugenii	49.64	6.00e-72	265.00
IUUC-Mor-057157	Magnaporthe oryzae	24.20	1.00e-32	135.00
IUUC-Mpo-057518	Magnaporthe poae	24.32	2.00e-34	141.00
IUUC-Mtr-058125	Medicago truncatula	29.93	2.00e-53	204.00
IUUC-Mga-059906	Meleagris gallopavo	57.02	1.00e-159	556.00
IUUC-Mvi-060374	Microbotryum violaceum	32.02	6.00e-31	129.00
IUUC-Mmr-061786	Microcebus murinus	56.90	1.00e-152	533.00
IUUC-Mdo-062453	Monodelphis domestica	58.46	3.00e-157	548.00
IUUC-Mmu-063521	Mus musculus	56.32	1.00e-146	512.00
IUUC-Mac-065119	Musa acuminata	26.48	2.00e-42	167.00
IUUC-Mpu-066274	Mustela putorius furo	57.11	1.00e-153	536.00
IUUC-Mlu-067202	Myotis lucifugus	56.83	5.00e-145	507.00
IUUC-Nfi-068564	Neosartorya fischeri	26.07	3.00e-40	160.00
IUUC-Ncr-068823	Neurospora crassa	23.54	3.00e-35	143.00
IUUC-Nle-068987	Nomascus leucogenys	57.08	1.00e-151	530.00
IUUC-Opr-070453	Ochotona princeps	57.33	1.00e-152	533.00
IUUC-Ont-072611	Oreochromis niloticus	67.43	0.00e+00	673.00
IUUC-Oan-073738	Ornithorhynchus anatinus	58.98	2.00e-160	558.00
IUUC-Ocu-074396	Oryctolagus cuniculus	57.69	1.00e-152	532.00
IUUC-Oba-075472	Oryza barthii	29.78	1.00e-45	177.00
IUUC-Obr-076277	Oryza brachyantha	29.87	1.00e-48	187.00
IUUC-Ogl-077046	Oryza glaberrima	29.57	3.00e-44	173.00
IUUC-Ogu-078634	Oryza glumaepatula	29.78	6.00e-46	179.00
IUUC-Oin-080080	Oryza indica	30.38	1.00e-51	197.00
IUUC-Olo-080828	Oryza longistaminata	30.44	8.00e-49	189.00
IUUC-Ome-081387	Oryza meridionalis	29.52	2.00e-54	206.00
IUUC-Oni-082934	Oryza nivara	29.78	4.00e-46	179.00
IUUC-Opu-083719	Oryza punctata	30.35	9.00e-47	181.00
IUUC-Oru-084518	Oryza rufipogon	29.78	6.00e-46	179.00
IUUC-Ola-087312	Oryzias latipes	65.30	0.00e+00	654.00
IUUC-Olu-087661	Ostreococcus lucimarinus	29.63	2.00e-51	197.00
IUUC-Oga-089129	Otolemur garnettii	56.90	4.00e-153	534.00
IUUC-Oar-089839	Ovis aries	56.90	5.00e-153	534.00
IUUC-Ptr-091626	Pan troglodytes	57.21	1.00e-151	529.00
IUUC-Pan-092798	Papio anubis	56.99	2.00e-151	528.00
IUUC-Psi-093253	Pelodiscus sinensis	58.05	3.00e-163	568.00
IUUC-Pma-094512	Petromyzon marinus	52.16	8.00e-140	490.00
IUUC-Pno-094937	Phaeosphaeria nodorum	22.60	1.00e-33	137.00
IUUC-Ppa-095211	Physcomitrella patens	31.74	2.00e-63	236.00
IUUC-Pfo-097049	Poecilia formosa	62.94	3.00e-175	608.00
IUUC-Pab-097911	Pongo abelii	57.21	2.00e-151	529.00
IUUC-Pop-099841	Populus trichocarpa	30.51	2.00e-55	210.00
IUUC-Pca-100814	Procavia capensis	51.65	2.00e-108	385.00
IUUC-Ppe-101972	Prunus persica	30.12	5.00e-51	195.00
IUUC-Pva-103038	Pteropus vampyrus	56.25	2.00e-150	525.00
IUUC-Pgr-103277	Puccinia graminis	27.67	9.00e-42	164.00
IUUC-Ptt-103855	Puccinia triticina	25.53	7.00e-40	158.00
IUUC-Pte-104113	Pyrenophora teres	23.06	3.00e-30	126.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	23.06	3.00e-32	133.00
IUUC-Rno-106003	Rattus norvegicus	55.38	8.00e-146	510.00
IUUC-Sce-106287	Saccharomyces cerevisiae	24.43	2.00e-23	103.00
IUUC-Sha-106652	Sarcophilus harrisii	58.26	7.00e-159	553.00
IUUC-Spo-108167	Schizosaccharomyces pombe	28.51	4.00e-46	179.00
IUUC-Smo-109393	Selaginella moellendorffii	30.63	1.00e-52	200.00
IUUC-Sit-110529	Setaria italica	32.37	1.00e-52	201.00
IUUC-Sly-111829	Solanum lycopersicum	31.18	9.00e-59	221.00
IUUC-Stu-112811	Solanum tuberosum	31.56	4.00e-58	219.00
IUUC-Sar-113259	Sorex araneus	52.35	2.00e-76	279.00
IUUC-Sbi-114591	Sorghum bicolor	34.36	2.00e-42	167.00
IUUC-Sre-115227	Sporisorium reilianum	27.63	7.00e-44	172.00
IUUC-Ssc-115293	Sus scrofa	57.45	1.00e-154	539.00
IUUC-Tgu-117335	Taeniopygia guttata	58.24	2.00e-164	572.00
IUUC-Tru-118458	Takifugu rubripes	69.87	0.00e+00	681.00
IUUC-Tsy-119475	Tarsius syrichta	56.45	2.00e-127	449.00
IUUC-Tni-119827	Tetraodon nigroviridis	67.51	0.00e+00	655.00
IUUC-Tca-121023	Theobroma cacao	31.25	2.00e-56	214.00
IUUC-Tre-121965	Trichoderma reesei	25.60	9.00e-39	154.00
IUUC-Tvi-122564	Trichoderma virens	25.50	4.00e-38	152.00
IUUC-Tae-124793	Triticum aestivum	30.82	4.00e-47	182.00
IUUC-Tur-126258	Triticum urartu	25.93	9.00e-41	161.00
IUUC-Tbe-127227	Tupaia belangeri	62.14	1.00e-46	181.00
IUUC-Ttr-128984	Tursiops truncatus	46.09	3.00e-108	385.00
IUUC-Uma-129565	Ustilago maydis	25.81	2.00e-39	157.00
IUUC-Vpa-130301	Vicugna pacos	57.11	5.00e-153	534.00
IUUC-Vvi-131244	Vitis vinifera	29.96	4.00e-57	216.00
IUUC-Xtr-132880	Xenopus tropicalis	51.82	2.00e-143	502.00
IUUC-Xma-134055	Xiphophorus maculatus	70.32	0.00e+00	684.00
IUUC-Yli-134342	Yarrowia lipolytica	29.61	3.00e-51	196.00
IUUC-Zma-135021	Zea mays	33.80	3.00e-46	180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence