iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-08	35.9	26	82

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...........pglknssskefrCPlCr 46
           C+iCle+f +++++lpC+H  +++C   +            g    s ++frCP Cr
   Q: 26   CPICLEMFTKPVVILPCQHNLCRKCASDIfqasnpylptrGGTTVASGGRFRCPSCR 82
           *************************744445557779999888889**********8 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSTSLNYKSF SKEQQTMDNL EKQLICPICL EMFTKPVVIL PCQHNLCRKC ASDIFQASNP 60
YLPTRGGTTV ASGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESTRPEKKLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTCCACA GAGAGAGAGA CATAAAGGAC ACTTGATCAT ACAGTCCTTG GAATTATTTC 60
CAGGAACCAC TTACAGAAGC CGTTCGGGAG CACCTTTCCC TTGGCAGCAC ACTCAGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR017903--COS_domain
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51262--COS
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0042802--F:identical protein binding
GO:0008270--F:zinc ion binding

KEGG

mmu:381485

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002421	Ailuropoda melanoleuca	83.94	0.00e+00	829.00
IUUC-Apl-003341	Anas platyrhynchos	69.88	0.00e+00	663.00
IUUC-Aca-005384	Anolis carolinensis	65.75	2.00e-176	611.00
IUUC-Ame-010720	Astyanax mexicanus	72.15	1.00e-138	486.00
IUUC-Bta-013040	Bos taurus	80.29	0.00e+00	789.00
IUUC-Cja-019932	Callithrix jacchus	85.04	0.00e+00	820.00
IUUC-Cfa-020450	Canis familiaris	83.45	0.00e+00	863.00
IUUC-Cpo-021767	Cavia porcellus	82.78	0.00e+00	864.00
IUUC-Csa-023600	Chlorocebus sabaeus	83.15	0.00e+00	832.00
IUUC-Cho-024753	Choloepus hoffmanni	72.21	0.00e+00	682.00
IUUC-Dre-028701	Danio rerio	70.89	1.00e-137	482.00
IUUC-Dno-030008	Dasypus novemcinctus	81.19	0.00e+00	813.00
IUUC-Ete-032274	Echinops telfairi	75.00	0.00e+00	733.00
IUUC-Eca-034326	Equus caballus	83.97	0.00e+00	792.00
IUUC-Fca-035385	Felis catus	82.55	0.00e+00	766.00
IUUC-Fal-036679	Ficedula albicollis	88.57	1.00e-174	606.00
IUUC-Gmo-039021	Gadus morhua	64.56	1.00e-117	416.00
IUUC-Gga-040576	Gallus gallus	88.25	5.00e-172	597.00
IUUC-Gac-042165	Gasterosteus aculeatus	66.56	6.00e-132	463.00
IUUC-Ggo-044496	Gorilla gorilla	83.82	0.00e+00	808.00
IUUC-Hsa-046337	Homo sapiens	83.64	0.00e+00	809.00
IUUC-Lch-050504	Latimeria chalumnae	64.16	2.00e-178	618.00
IUUC-Loc-052717	Lepisosteus oculatus	56.22	6.00e-160	557.00
IUUC-Laf-053838	Loxodonta africana	77.33	0.00e+00	806.00
IUUC-Mcc-054690	Macaca mulatta	83.45	0.00e+00	800.00
IUUC-Meu-056782	Macropus eugenii	66.54	2.00e-180	625.00
IUUC-Mga-060112	Meleagris gallopavo	87.70	5.00e-171	594.00
IUUC-Mmr-061229	Microcebus murinus	82.20	0.00e+00	833.00
IUUC-Mdo-062397	Monodelphis domestica	74.19	0.00e+00	725.00
IUUC-Mpu-066503	Mustela putorius furo	83.91	0.00e+00	844.00
IUUC-Mlu-068160	Myotis lucifugus	95.35	3.00e-98	350.00
IUUC-Nle-069170	Nomascus leucogenys	83.79	0.00e+00	830.00
IUUC-Ont-072082	Oreochromis niloticus	68.47	2.00e-131	462.00
IUUC-Oan-072715	Ornithorhynchus anatinus	70.28	0.00e+00	694.00
IUUC-Ocu-074747	Oryctolagus cuniculus	82.32	0.00e+00	751.00
IUUC-Ola-086646	Oryzias latipes	57.57	1.00e-128	453.00
IUUC-Oga-087995	Otolemur garnettii	83.79	0.00e+00	836.00
IUUC-Oar-089844	Ovis aries	80.29	0.00e+00	800.00
IUUC-Ptr-091556	Pan troglodytes	83.82	0.00e+00	807.00
IUUC-Pan-092224	Papio anubis	83.82	0.00e+00	801.00
IUUC-Psi-093856	Pelodiscus sinensis	71.98	0.00e+00	739.00
IUUC-Pma-094534	Petromyzon marinus	54.46	1.00e-99	356.00
IUUC-Pfo-096596	Poecilia formosa	61.54	5.00e-128	451.00
IUUC-Pca-100510	Procavia capensis	76.51	0.00e+00	794.00
IUUC-Pva-102962	Pteropus vampyrus	81.18	0.00e+00	747.00
IUUC-Rno-105696	Rattus norvegicus	93.39	0.00e+00	886.00
IUUC-Sha-106825	Sarcophilus harrisii	75.05	0.00e+00	741.00
IUUC-Ssc-116332	Sus scrofa	82.05	0.00e+00	770.00
IUUC-Tgu-117208	Taeniopygia guttata	88.25	1.00e-174	606.00
IUUC-Tru-118744	Takifugu rubripes	65.54	1.00e-129	456.00
IUUC-Tsy-119352	Tarsius syrichta	79.82	0.00e+00	825.00
IUUC-Tni-120413	Tetraodon nigroviridis	67.41	2.00e-128	451.00
IUUC-Tbe-127821	Tupaia belangeri	98.51	2.00e-121	429.00
IUUC-Ttr-128545	Tursiops truncatus	82.02	0.00e+00	756.00
IUUC-Vpa-130699	Vicugna pacos	93.90	0.00e+00	655.00
IUUC-Xtr-132207	Xenopus tropicalis	63.51	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence