iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019528

UUCD1 version

UUC-CaJ-00710

Ensembl Protein ID

ENSCJAP00000041435.2

UniProt Accession

F7HFR5; F7HFR5_CALJA

Genbank Protein ID

JAB02679.1; JAB11930.1; JAB29497.1; JAB43852.1

Protein Name

Suppressor of cytokine signaling 6

Genbank Nucleotide ID

ACFV01042339; GAMS01011206; GAMR01004435; GAMP01008903

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000022864.2	ENSCJAT00000043849.2	ENSCJAP00000041435.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.50e-17	62.1	487	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 487  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 534
           5788999********************888...***************997 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINSED 60
EKGGKNRSKS ESLMGTLKRR LSAKQKKGKA GTPSGSCADE DTFSSSSAPI VFKDVRAQRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAGGCGA GCGCGGCAGT CGCGCCGGCG CTGGGCGAGG AAGCGGAGCC GGGCCGCCTC 60
CGGGTGAGCG TTTGGGGAGC CTGGGAGGGA GGCTGGGACC GGGCTTCGCC GTCCGCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

cjc:100386814

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	93.83	0.00e+00	945.00
IUUC-Atr-002940	Amborella trichopoda	27.27	1.20e-01	30.80
IUUC-Apl-004035	Anas platyrhynchos	90.84	0.00e+00	893.00
IUUC-Aca-004782	Anolis carolinensis	88.43	0.00e+00	867.00
IUUC-Ame-011790	Astyanax mexicanus	70.02	0.00e+00	644.00
IUUC-Bta-012579	Bos taurus	95.17	4.00e-108	384.00
IUUC-Bol-015843	Brassica oleracea	28.77	3.20e-02	33.10
IUUC-Cfa-020678	Canis familiaris	94.77	0.00e+00	963.00
IUUC-Cpo-021947	Cavia porcellus	95.51	0.00e+00	1000.00
IUUC-Csa-023935	Chlorocebus sabaeus	98.13	0.00e+00	996.00
IUUC-Cho-024477	Choloepus hoffmanni	91.96	0.00e+00	957.00
IUUC-Cin-025413	Ciona intestinalis	68.24	4.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	7.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	26.04	1.10e-01	32.00
IUUC-Dre-027636	Danio rerio	68.47	0.00e+00	635.00
IUUC-Dno-029048	Dasypus novemcinctus	93.46	0.00e+00	950.00
IUUC-Dor-030401	Dipodomys ordii	89.93	0.00e+00	916.00
IUUC-Ete-033116	Echinops telfairi	49.82	1.00e-58	219.00
IUUC-Eca-033825	Equus caballus	92.71	0.00e+00	924.00
IUUC-Fca-036253	Felis catus	91.21	0.00e+00	874.00
IUUC-Fal-037614	Ficedula albicollis	90.47	0.00e+00	890.00
IUUC-Fox-037898	Fusarium oxysporum	27.16	2.00e-02	32.70
IUUC-Gmo-038928	Gadus morhua	69.37	0.00e+00	669.00
IUUC-Gga-040177	Gallus gallus	90.28	0.00e+00	887.00
IUUC-Gac-042263	Gasterosteus aculeatus	70.85	0.00e+00	701.00
IUUC-Ggo-045288	Gorilla gorilla	97.57	0.00e+00	995.00
IUUC-Hsa-046409	Homo sapiens	97.94	0.00e+00	998.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	92.90	0.00e+00	924.00
IUUC-Lch-050354	Latimeria chalumnae	83.77	0.00e+00	867.00
IUUC-Loc-052319	Lepisosteus oculatus	81.53	0.00e+00	817.00
IUUC-Laf-054070	Loxodonta africana	92.71	0.00e+00	912.00
IUUC-Mcc-055045	Macaca mulatta	97.76	0.00e+00	992.00
IUUC-Meu-055917	Macropus eugenii	90.65	0.00e+00	954.00
IUUC-Mga-059273	Meleagris gallopavo	90.65	0.00e+00	887.00
IUUC-Mmr-061597	Microcebus murinus	97.01	0.00e+00	986.00
IUUC-Mdo-062492	Monodelphis domestica	66.67	7.00e-114	403.00
IUUC-Mmu-063374	Mus musculus	83.80	0.00e+00	836.00
IUUC-Mpu-065967	Mustela putorius furo	87.85	0.00e+00	899.00
IUUC-Mlu-067532	Myotis lucifugus	90.28	0.00e+00	924.00
IUUC-Nle-069373	Nomascus leucogenys	98.32	0.00e+00	998.00
IUUC-Opr-070873	Ochotona princeps	90.09	0.00e+00	954.00
IUUC-Ont-072498	Oreochromis niloticus	71.40	0.00e+00	728.00
IUUC-Oan-072943	Ornithorhynchus anatinus	71.22	2.00e-98	352.00
IUUC-Ocu-073870	Oryctolagus cuniculus	94.21	0.00e+00	952.00
IUUC-Ola-086866	Oryzias latipes	88.94	2.00e-104	371.00
IUUC-Oga-089057	Otolemur garnettii	91.21	0.00e+00	930.00
IUUC-Oar-089841	Ovis aries	62.06	5.00e-169	587.00
IUUC-Ptr-091054	Pan troglodytes	97.94	0.00e+00	997.00
IUUC-Pma-094253	Petromyzon marinus	44.29	6.00e-99	354.00
IUUC-Pfo-097179	Poecilia formosa	64.51	3.00e-177	614.00
IUUC-Pab-097702	Pongo abelii	98.32	0.00e+00	999.00
IUUC-Pca-100671	Procavia capensis	86.64	2.00e-128	452.00
IUUC-Rno-106044	Rattus norvegicus	81.49	0.00e+00	827.00
IUUC-Sha-107139	Sarcophilus harrisii	89.96	0.00e+00	875.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.80e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.80e-01	30.00
IUUC-Ssc-115343	Sus scrofa	92.34	0.00e+00	956.00
IUUC-Tgu-117061	Taeniopygia guttata	90.47	0.00e+00	892.00
IUUC-Tni-119829	Tetraodon nigroviridis	68.02	0.00e+00	644.00
IUUC-Tae-123723	Triticum aestivum	27.50	1.20e-02	35.40
IUUC-Ttr-129148	Tursiops truncatus	91.21	0.00e+00	897.00
IUUC-Vpa-130780	Vicugna pacos	88.76	0.00e+00	869.00
IUUC-Vvi-130966	Vitis vinifera	32.69	6.20e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	82.77	0.00e+00	867.00
IUUC-Xma-133904	Xiphophorus maculatus	68.39	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence