iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059192

UUCD1 version

UUC-MeG-00694

Ensembl Protein ID

ENSMGAP00000014160.2

UniProt Accession

G1NL10; G1NL10_MELGA

Protein Name

Uncharacterized protein

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013400.2	ENSMGAT00000015084.2	ENSMGAP00000014160.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.60e-19	69.6	239	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vCl+Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 239  VCLFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 286
           8*********88.6*******************.*******7.******75 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

DWQPPFACEV QSFRFTPRIQ RLNELEAMTR VKLDFLDQLA KFWELQGSNL KIPVVERKIL 60
DLYGLSKIVA GKGGFEVVTK EKKWSKVASR LGYLPGKGTG SLLKSHYERI LYPYELFQSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTGGCAGC CTCCGTTTGC CTGTGAAGTA CAAAGTTTTC GTTTCACTCC ACGAATTCAG 60
CGCCTGAATG AACTGGAGGT GAGCCTTTCC ACTGTTGATA CAGTTTTGTG TTTACACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	83.06	0.00e+00	2384.00
IUUC-Apl-004141	Anas platyrhynchos	89.59	0.00e+00	2633.00
IUUC-Aca-004952	Anolis carolinensis	83.72	0.00e+00	2475.00
IUUC-Ame-011323	Astyanax mexicanus	69.27	0.00e+00	1635.00
IUUC-Bta-012902	Bos taurus	82.14	0.00e+00	2417.00
IUUC-Cja-018988	Callithrix jacchus	80.83	0.00e+00	2282.00
IUUC-Cfa-020212	Canis familiaris	82.21	0.00e+00	2347.00
IUUC-Cpo-022221	Cavia porcellus	80.40	0.00e+00	1645.00
IUUC-Csa-023575	Chlorocebus sabaeus	83.00	0.00e+00	2323.00
IUUC-Cho-024280	Choloepus hoffmanni	78.55	0.00e+00	2187.00
IUUC-Csv-026185	Ciona savignyi	41.59	0.00e+00	888.00
IUUC-Dre-027909	Danio rerio	66.70	0.00e+00	1369.00
IUUC-Dno-029473	Dasypus novemcinctus	82.27	0.00e+00	2238.00
IUUC-Dor-030281	Dipodomys ordii	89.91	0.00e+00	1197.00
IUUC-Ete-033144	Echinops telfairi	83.71	0.00e+00	834.00
IUUC-Eca-034265	Equus caballus	82.82	0.00e+00	2414.00
IUUC-Fca-035476	Felis catus	81.90	0.00e+00	2378.00
IUUC-Fal-037078	Ficedula albicollis	86.29	0.00e+00	2198.00
IUUC-Gga-040466	Gallus gallus	89.73	0.00e+00	2637.00
IUUC-Gac-042566	Gasterosteus aculeatus	65.47	0.00e+00	1800.00
IUUC-Ggo-044524	Gorilla gorilla	76.32	0.00e+00	2034.00
IUUC-Hsa-045821	Homo sapiens	83.30	0.00e+00	2414.00
IUUC-Lch-050630	Latimeria chalumnae	67.01	0.00e+00	1743.00
IUUC-Loc-051963	Lepisosteus oculatus	68.96	0.00e+00	1741.00
IUUC-Laf-053918	Loxodonta africana	77.17	0.00e+00	2088.00
IUUC-Mcc-055672	Macaca mulatta	81.97	0.00e+00	2414.00
IUUC-Mmr-060968	Microcebus murinus	81.37	0.00e+00	2399.00
IUUC-Mdo-062945	Monodelphis domestica	83.23	0.00e+00	2313.00
IUUC-Mmu-063614	Mus musculus	82.45	0.00e+00	2410.00
IUUC-Mpu-066349	Mustela putorius furo	82.77	0.00e+00	2293.00
IUUC-Mlu-067363	Myotis lucifugus	82.45	0.00e+00	2447.00
IUUC-Nle-070142	Nomascus leucogenys	83.30	0.00e+00	2427.00
IUUC-Ont-072471	Oreochromis niloticus	68.98	0.00e+00	1592.00
IUUC-Oan-072797	Ornithorhynchus anatinus	66.67	0.00e+00	1563.00
IUUC-Ocu-074164	Oryctolagus cuniculus	82.35	0.00e+00	2463.00
IUUC-Ola-087076	Oryzias latipes	66.35	0.00e+00	1736.00
IUUC-Oga-088350	Otolemur garnettii	81.05	0.00e+00	2332.00
IUUC-Oar-090045	Ovis aries	82.20	0.00e+00	2424.00
IUUC-Ptr-091199	Pan troglodytes	82.69	0.00e+00	2404.00
IUUC-Pan-092094	Papio anubis	79.31	0.00e+00	2177.00
IUUC-Psi-093550	Pelodiscus sinensis	85.03	0.00e+00	2469.00
IUUC-Pfo-097266	Poecilia formosa	67.08	0.00e+00	1765.00
IUUC-Pab-098576	Pongo abelii	83.42	0.00e+00	2415.00
IUUC-Pca-100123	Procavia capensis	75.30	0.00e+00	1256.00
IUUC-Pva-103109	Pteropus vampyrus	79.37	0.00e+00	2313.00
IUUC-Rno-105664	Rattus norvegicus	82.69	0.00e+00	2406.00
IUUC-Sha-107506	Sarcophilus harrisii	81.67	0.00e+00	2143.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	61.60
IUUC-Sar-113052	Sorex araneus	81.96	0.00e+00	2401.00
IUUC-Tgu-116613	Taeniopygia guttata	88.37	0.00e+00	2561.00
IUUC-Tru-118604	Takifugu rubripes	66.74	0.00e+00	1790.00
IUUC-Tni-120779	Tetraodon nigroviridis	66.67	0.00e+00	1771.00
IUUC-Ttr-129242	Tursiops truncatus	80.89	0.00e+00	2323.00
IUUC-Vpa-130429	Vicugna pacos	70.21	0.00e+00	1099.00
IUUC-Xtr-131762	Xenopus tropicalis	66.64	0.00e+00	1738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence