iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005038

Ensembl Protein ID

ENSACAP00000002608.2

UniProt Accession

G1KB14; G1KB14_ANOCA

Protein Name

Serine/threonine-protein phosphatase

Gene Name

PPP2CA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002653.3	ENSACAT00000002674.3	ENSACAP00000002608.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	99.03	0.00e+00	645.00	IUUC-Hsa-046871

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MEEKVFTKEL DQWVEQLNEC KQLSEGQVKS LCEKAKEILT KESNVQEVRC PVTVCGDVHG 60
QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYRER ITILRGNHES 120

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Nucleotide Sequence
(Fasta)

ATGGAGGAGA AGGTCTTCAC GAAGGAGCTG GACCAGTGGG TGGAGCAGCT GAACGAGTGC 60
AAGCAGCTCT CCGAGGGGCA AGTGAAGAGC CTCTGTGAGA AGGTGAGCAG CAGGCCCTGG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR004843--Calcineurin-like_PHP_ApaH
IPR029052--Metallo-depent_PP-like
IPR006186--Ser/Thr-sp_prot-phosphatase

PROSITE

PS00125--SER_THR_PHOSPHATASE

Pfam

PF00149--Metallophos

PRINTS

PR00114--STPHPHTASE

SMART

SM00156--PP2Ac

Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0000159--C:protein phosphatase type 2A complex
GO:0004721--F:phosphoprotein phosphatase activity
GO:0007498--P:mesoderm development
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0071902--P:positive regulation of protein serine/threonine kinase activity

KEGG

acs:100568233

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000073	Aegilops tauschii	81.06	2.00e-153	534.00
IUUC-Aml-001862	Ailuropoda melanoleuca	99.03	0.00e+00	645.00
IUUC-Atr-002565	Amborella trichopoda	81.73	2.00e-154	538.00
IUUC-Apl-004163	Anas platyrhynchos	98.06	0.00e+00	634.00
IUUC-Aly-005921	Arabidopsis lyrata	79.87	4.00e-153	533.00
IUUC-Ath-007164	Arabidopsis thaliana	79.87	6.00e-153	532.00
IUUC-Ame-010907	Astyanax mexicanus	98.06	0.00e+00	641.00
IUUC-Bgr-012186	Blumeria graminis	83.71	1.00e-158	551.00
IUUC-Bta-013583	Bos taurus	99.03	0.00e+00	645.00
IUUC-Bci-013884	Botrytis cinerea	84.14	1.00e-160	558.00
IUUC-Bdi-014993	Brachypodium distachyon	81.06	2.00e-153	534.00
IUUC-Bra-017702	Brassica rapa	79.87	3.00e-154	537.00
IUUC-Cja-019549	Callithrix jacchus	99.03	0.00e+00	645.00
IUUC-Cfa-020295	Canis familiaris	99.03	0.00e+00	645.00
IUUC-Cpo-022311	Cavia porcellus	99.03	0.00e+00	645.00
IUUC-Cre-022625	Chlamydomonas reinhardtii	78.10	2.00e-147	514.00
IUUC-Csa-023283	Chlorocebus sabaeus	99.03	0.00e+00	645.00
IUUC-Cin-025581	Ciona intestinalis	92.74	2.00e-173	600.00
IUUC-Csv-026026	Ciona savignyi	91.18	3.00e-151	526.00
IUUC-Cgl-026758	Colletotrichum gloeosporioides	84.36	1.00e-160	558.00
IUUC-Cne-026997	Cryptococcus neoformans	85.05	3.00e-160	557.00
IUUC-Cme-027101	Cyanidioschyzon merolae	82.20	8.00e-158	549.00
IUUC-Dre-027487	Danio rerio	97.41	0.00e+00	639.00
IUUC-Dno-028872	Dasypus novemcinctus	99.03	0.00e+00	645.00
IUUC-Ete-032859	Echinops telfairi	99.03	0.00e+00	645.00
IUUC-Fca-036395	Felis catus	99.03	0.00e+00	645.00
IUUC-Fal-036826	Ficedula albicollis	100.00	7.00e-167	578.00
IUUC-Fox-037783	Fusarium oxysporum	84.04	6.00e-161	559.00
IUUC-Fso-038215	Fusarium solani	84.04	2.00e-160	558.00
IUUC-Gmo-038520	Gadus morhua	96.10	2.00e-179	621.00
IUUC-Ggr-039745	Gaeumannomyces graminis	84.04	6.00e-160	556.00
IUUC-Gga-040663	Gallus gallus	100.00	0.00e+00	649.00
IUUC-Gac-042221	Gasterosteus aculeatus	96.76	0.00e+00	635.00
IUUC-Gma-042753	Glycine max	81.06	9.00e-154	535.00
IUUC-Ggo-044960	Gorilla gorilla	99.03	0.00e+00	645.00
IUUC-Hsa-046871	Homo sapiens	99.03	0.00e+00	645.00
IUUC-Itr-048646	Ictidomys tridecemlineatus	99.03	0.00e+00	645.00
IUUC-Kpa-049311	Komagataella pastoris	76.16	3.00e-143	501.00
IUUC-Lch-050295	Latimeria chalumnae	98.06	0.00e+00	642.00
IUUC-Lpe-051261	Leersia perrieri	81.06	1.00e-154	538.00
IUUC-Loc-052336	Lepisosteus oculatus	98.38	0.00e+00	642.00
IUUC-Lma-053211	Leptosphaeria maculans	84.04	1.00e-160	558.00
IUUC-Laf-053835	Loxodonta africana	99.03	0.00e+00	645.00
IUUC-Mcc-055756	Macaca mulatta	99.03	0.00e+00	645.00
IUUC-Meu-056068	Macropus eugenii	74.43	4.00e-129	453.00
IUUC-Mor-057272	Magnaporthe oryzae	84.36	1.00e-160	558.00
IUUC-Mpo-057478	Magnaporthe poae	84.04	5.00e-160	556.00
IUUC-Mtr-057736	Medicago truncatula	80.07	5.00e-152	529.00
IUUC-Mla-059001	Melampsora laricipopulina	85.48	1.00e-161	561.00
IUUC-Mga-059904	Meleagris gallopavo	97.24	4.00e-170	590.00
IUUC-Mvi-060467	Microbotryum violaceum	85.53	9.00e-162	562.00
IUUC-Mmr-060867	Microcebus murinus	99.03	0.00e+00	645.00
IUUC-Mdo-062353	Monodelphis domestica	99.03	0.00e+00	645.00
IUUC-Mmu-064204	Mus musculus	98.71	0.00e+00	644.00
IUUC-Mac-064924	Musa acuminata	82.39	1.00e-155	541.00
IUUC-Mpu-066183	Mustela putorius furo	99.03	0.00e+00	645.00
IUUC-Mlu-067115	Myotis lucifugus	99.03	0.00e+00	644.00
IUUC-Ncr-068958	Neurospora crassa	84.36	1.00e-160	558.00
IUUC-Nle-069365	Nomascus leucogenys	99.03	0.00e+00	645.00
IUUC-Opr-071012	Ochotona princeps	99.03	0.00e+00	645.00
IUUC-Ont-071469	Oreochromis niloticus	96.76	0.00e+00	635.00
IUUC-Oan-072869	Ornithorhynchus anatinus	98.92	3.00e-167	580.00
IUUC-Ocu-074394	Oryctolagus cuniculus	99.03	0.00e+00	645.00
IUUC-Oba-075432	Oryza barthii	81.06	2.00e-154	538.00
IUUC-Ogl-077436	Oryza glaberrima	82.06	2.00e-154	538.00
IUUC-Ogu-078351	Oryza glumaepatula	81.06	2.00e-154	538.00
IUUC-Oin-080218	Oryza indica	82.06	2.00e-154	537.00
IUUC-Olo-080223	Oryza longistaminata	82.06	2.00e-154	538.00
IUUC-Ome-081581	Oryza meridionalis	82.06	2.00e-154	537.00
IUUC-Oni-082094	Oryza nivara	82.06	2.00e-154	537.00
IUUC-Opu-083544	Oryza punctata	81.73	2.00e-154	537.00
IUUC-Oru-084975	Oryza rufipogon	82.06	2.00e-154	537.00
IUUC-Osa-085945	Oryza sativa	82.06	2.00e-154	537.00
IUUC-Ola-087141	Oryzias latipes	97.09	0.00e+00	637.00
IUUC-Oga-087919	Otolemur garnettii	99.03	0.00e+00	645.00
IUUC-Oar-089240	Ovis aries	100.00	7.00e-167	578.00
IUUC-Ptr-091367	Pan troglodytes	98.38	0.00e+00	639.00
IUUC-Pan-091956	Papio anubis	99.03	0.00e+00	645.00
IUUC-Psi-094099	Pelodiscus sinensis	97.39	0.00e+00	629.00
IUUC-Pma-094369	Petromyzon marinus	90.12	1.00e-88	318.00
IUUC-Pno-094872	Phaeosphaeria nodorum	77.33	3.00e-137	480.00
IUUC-Ppa-095520	Physcomitrella patens	83.72	2.00e-158	550.00
IUUC-Pfo-097359	Poecilia formosa	97.09	0.00e+00	636.00
IUUC-Pop-099210	Populus trichocarpa	81.40	2.00e-154	537.00
IUUC-Pca-100122	Procavia capensis	85.76	9.00e-154	535.00
IUUC-Ppe-101822	Prunus persica	81.06	4.00e-153	533.00
IUUC-Pva-102237	Pteropus vampyrus	88.67	2.00e-162	564.00
IUUC-Pgr-103259	Puccinia graminis	84.82	2.00e-160	557.00
IUUC-Pte-104116	Pyrenophora teres	84.04	2.00e-160	558.00
IUUC-Pyt-104768	Pyrenophora triticirepentis	84.04	2.00e-160	558.00
IUUC-Rno-104853	Rattus norvegicus	98.71	0.00e+00	644.00
IUUC-Sce-106338	Saccharomyces cerevisiae	75.83	2.00e-144	505.00
IUUC-Sha-107562	Sarcophilus harrisii	99.03	0.00e+00	646.00
IUUC-Sja-107705	Schizosaccharomyces japonicus	81.06	6.00e-154	536.00
IUUC-Spo-108240	Schizosaccharomyces pombe	79.73	5.00e-152	530.00
IUUC-Smo-109421	Selaginella moellendorffii	84.11	2.00e-158	551.00
IUUC-Sit-110313	Setaria italica	81.40	2.00e-154	538.00
IUUC-Sly-111492	Solanum lycopersicum	81.73	1.00e-154	538.00
IUUC-Stu-112108	Solanum tuberosum	81.73	1.00e-154	538.00
IUUC-Sar-113253	Sorex araneus	94.79	8.00e-174	602.00
IUUC-Sbi-114125	Sorghum bicolor	81.06	1.00e-153	535.00
IUUC-Sre-115054	Sporisorium reilianum	86.05	3.00e-161	560.00
IUUC-Tgu-117419	Taeniopygia guttata	100.00	0.00e+00	649.00
IUUC-Tru-117531	Takifugu rubripes	96.44	0.00e+00	633.00
IUUC-Tsy-119543	Tarsius syrichta	99.03	0.00e+00	645.00
IUUC-Tni-120904	Tetraodon nigroviridis	96.12	0.00e+00	630.00
IUUC-Tca-120941	Theobroma cacao	82.12	1.00e-154	538.00
IUUC-Tre-121939	Trichoderma reesei	82.74	7.00e-158	549.00
IUUC-Tvi-122516	Trichoderma virens	82.74	2.00e-158	551.00
IUUC-Tae-124897	Triticum aestivum	81.06	2.00e-153	534.00
IUUC-Tbe-127639	Tupaia belangeri	99.03	0.00e+00	645.00
IUUC-Ttr-128718	Tursiops truncatus	99.35	0.00e+00	646.00
IUUC-Uma-129470	Ustilago maydis	86.05	3.00e-161	560.00
IUUC-Vvi-131390	Vitis vinifera	81.06	1.00e-153	535.00
IUUC-Xtr-132784	Xenopus tropicalis	98.38	0.00e+00	642.00
IUUC-Xma-133450	Xiphophorus maculatus	96.12	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence