iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033626

Ensembl Protein ID

ENSECAP00000021664.1

UniProt Accession

F6WYL3; F6WYL3_HORSE

Protein Name

Histone-lysine N-methyltransferase

Gene Name

WHSC1L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024114.1	ENSECAT00000026005.1	ENSECAP00000021664.1
ENSECAG00000024114.1	ENSECAT00000026009.1	ENSECAP00000021668.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.70e-11	43.2	701	745

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC vC+++g+   sl+ Ce  C++ fH +Cl+l+   +lp+ + + C +C+
   Q: 701  AVCQVCESSGD---SLIPCEGeCCKHFHLECLGLA---SLPDGK-FVCMECK 745
           79********9...5********************...*****7.******7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNNSDI VEDGGQTPYE ATLQQGFQYP 60
PTTEDLPPLT NGYPPSISMY ETQTKYQSYN QYPNGSANGF GAVRNFSPAD YYHSDIPNTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCT CTTTCTCTTT CATGCAAGGG ATCATGGGAA ACACAATTCA GCAACCACCT 60
CAACTCATTG ACTCCGCCAA CATCCGTCAG GAGGATGCCT TTGATAACAA CAGTGACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	29.41	6.00e-12	66.20
IUUC-Aml-001809	Ailuropoda melanoleuca	90.67	0.00e+00	1665.00
IUUC-Apl-004027	Anas platyrhynchos	75.36	0.00e+00	1973.00
IUUC-Aca-005380	Anolis carolinensis	80.51	0.00e+00	2145.00
IUUC-Ame-011234	Astyanax mexicanus	64.38	0.00e+00	1169.00
IUUC-Bta-013575	Bos taurus	90.51	0.00e+00	2582.00
IUUC-Cja-020013	Callithrix jacchus	94.24	0.00e+00	2705.00
IUUC-Cfa-021060	Canis familiaris	93.42	0.00e+00	2593.00
IUUC-Cpo-021834	Cavia porcellus	90.98	0.00e+00	2506.00
IUUC-Csa-023370	Chlorocebus sabaeus	94.11	0.00e+00	2700.00
IUUC-Cho-025058	Choloepus hoffmanni	83.40	0.00e+00	1057.00
IUUC-Dre-027664	Danio rerio	58.89	0.00e+00	1397.00
IUUC-Dno-029302	Dasypus novemcinctus	91.48	0.00e+00	2543.00
IUUC-Fca-035556	Felis catus	93.69	0.00e+00	2639.00
IUUC-Fal-037101	Ficedula albicollis	80.04	0.00e+00	2119.00
IUUC-Gmo-038901	Gadus morhua	55.27	0.00e+00	1473.00
IUUC-Gga-040366	Gallus gallus	80.87	0.00e+00	2119.00
IUUC-Gac-042047	Gasterosteus aculeatus	59.74	0.00e+00	1281.00
IUUC-Ggo-044695	Gorilla gorilla	90.26	0.00e+00	2565.00
IUUC-Hsa-046080	Homo sapiens	93.76	0.00e+00	2698.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	92.86	0.00e+00	2619.00
IUUC-Lch-050544	Latimeria chalumnae	69.26	0.00e+00	1572.00
IUUC-Loc-052656	Lepisosteus oculatus	63.22	0.00e+00	1535.00
IUUC-Laf-054112	Loxodonta africana	92.87	0.00e+00	2608.00
IUUC-Mcc-054956	Macaca mulatta	94.31	0.00e+00	2699.00
IUUC-Meu-056051	Macropus eugenii	82.63	0.00e+00	1163.00
IUUC-Mga-060139	Meleagris gallopavo	82.91	0.00e+00	2203.00
IUUC-Mmr-060789	Microcebus murinus	92.09	0.00e+00	2645.00
IUUC-Mdo-062908	Monodelphis domestica	88.43	0.00e+00	2462.00
IUUC-Mmu-063165	Mus musculus	83.82	0.00e+00	2318.00
IUUC-Mpu-066002	Mustela putorius furo	93.34	0.00e+00	2622.00
IUUC-Nle-069417	Nomascus leucogenys	93.40	0.00e+00	2524.00
IUUC-Ont-071900	Oreochromis niloticus	57.14	0.00e+00	1560.00
IUUC-Oan-072857	Ornithorhynchus anatinus	87.88	0.00e+00	2453.00
IUUC-Ocu-073809	Oryctolagus cuniculus	92.44	0.00e+00	2591.00
IUUC-Obr-076122	Oryza brachyantha	30.12	6.00e-09	54.30
IUUC-Ola-087085	Oryzias latipes	56.91	0.00e+00	1523.00
IUUC-Oga-088289	Otolemur garnettii	91.75	0.00e+00	2562.00
IUUC-Oar-089398	Ovis aries	90.86	0.00e+00	2581.00
IUUC-Ptr-090510	Pan troglodytes	93.55	0.00e+00	2692.00
IUUC-Pan-092291	Papio anubis	94.24	0.00e+00	2705.00
IUUC-Psi-093547	Pelodiscus sinensis	84.52	0.00e+00	2258.00
IUUC-Pma-094747	Petromyzon marinus	48.49	0.00e+00	1053.00
IUUC-Pfo-096669	Poecilia formosa	57.29	0.00e+00	1529.00
IUUC-Pab-097727	Pongo abelii	94.04	0.00e+00	2680.00
IUUC-Pca-100474	Procavia capensis	84.29	0.00e+00	2255.00
IUUC-Pva-102539	Pteropus vampyrus	91.32	0.00e+00	2325.00
IUUC-Rno-105685	Rattus norvegicus	87.30	0.00e+00	2368.00
IUUC-Sha-107287	Sarcophilus harrisii	88.64	0.00e+00	2457.00
IUUC-Sar-113547	Sorex araneus	86.20	0.00e+00	2457.00
IUUC-Ssc-116208	Sus scrofa	93.97	0.00e+00	2712.00
IUUC-Tgu-117006	Taeniopygia guttata	82.72	0.00e+00	2221.00
IUUC-Tru-118375	Takifugu rubripes	56.93	0.00e+00	1565.00
IUUC-Tsy-119323	Tarsius syrichta	93.07	0.00e+00	2628.00
IUUC-Tni-120509	Tetraodon nigroviridis	57.26	0.00e+00	1559.00
IUUC-Tae-124687	Triticum aestivum	29.41	7.00e-12	65.90
IUUC-Ttr-128240	Tursiops truncatus	90.85	0.00e+00	2539.00
IUUC-Vpa-130666	Vicugna pacos	92.23	0.00e+00	2572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence