iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004350

UUCD1 version

UUC-AnC-00402

Ensembl Protein ID

ENSACAP00000007720.3

UniProt Accession

H9GD67; H9GD67_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007890.3	ENSACAT00000007885.3	ENSACAP00000007720.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.90e-104	348.6	480	818

Active Site

Position(s)	Description	Evidence
786	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 480  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFAYHKDSHCHWFSSLNC-----DNYSEFRLVGALMGLAVYNSITLDI 563
           589***************************************************88877.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +v+pel++ l+e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++ipV
   Q: 564  RFPPCCYKKLLSPpivpcdqstpvgisSVTIDDLCQVMPELAHGLNELLSY-EGNVEED-FYSTFQVFQEEFGVIKCYNLKPNGDKIPV 650
           **********999666666666666656**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l+v++ l+++i +q++af+ Gf++v+    l l+++ee+e+l+cG++e+d+++l+k+t+y+g y++++ +i++Fwev+ 
   Q: 651  TNQNRKEYVQLYVDFLLNKSIYKQFAAFYYGFHSVCASYALMLLRPEEVEILVCGSPELDMHALQKHTQYDG-YQKTDLTIRYFWEVVL 738
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           ef  e +k++L+F+Tgs+r+P+gG+ +l+   f i+k +as+d+lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 739  EFPLELQKKLLHFATGSDRVPVGGMTDLS---FKISKsEASTDWLPVAHTCFNQLCLPPYKTKKELKQKLTIGISNAEGFGLE 818
           *****************************...9999978889**************************************985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSLPPQPEPP PSDLLDKGGF LLDCSEMNEE APEPSEAAGP GHGGEEVLAA EEEQKAEEEE 60
EKEEGKGGKG GGGETSPTQP SEPRTASGGL EMGPKNDISP FSSFISTISQ KKDDTGNESP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTCAGGGA GAGGGGCATT TACTGAGGGA AATTGTTGAA ATTTGAGGGA TTGGGCACAA 60
AGAAGGAGCC TGGCAGCATC TTCTGGGCTG AGGGACAGAT GAGAAGTACA TTTCTGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

acs:100567730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	81.06	0.00e+00	1265.00
IUUC-Apl-003589	Anas platyrhynchos	84.13	0.00e+00	1274.00
IUUC-Ago-007908	Ashbya gossypii	34.80	4.00e-82	299.00
IUUC-Acl-008288	Aspergillus clavatus	34.38	5.00e-96	346.00
IUUC-Afl-008402	Aspergillus flavus	33.50	2.00e-90	326.00
IUUC-Afu-008762	Aspergillus fumigatus	33.99	5.00e-94	339.00
IUUC-Ani-009176	Aspergillus nidulans	34.22	2.00e-91	330.00
IUUC-Ang-009791	Aspergillus niger	34.42	2.00e-91	330.00
IUUC-Aor-009921	Aspergillus oryzae	33.33	1.00e-89	324.00
IUUC-Ate-010295	Aspergillus terreus	34.98	8.00e-100	358.00
IUUC-Ame-010660	Astyanax mexicanus	80.94	3.00e-150	523.00
IUUC-Bgr-011981	Blumeria graminis	37.62	1.00e-91	331.00
IUUC-Bta-012945	Bos taurus	81.06	0.00e+00	1244.00
IUUC-Bci-013697	Botrytis cinerea	39.12	1.00e-82	301.00
IUUC-Cja-019263	Callithrix jacchus	79.65	0.00e+00	1224.00
IUUC-Cfa-020486	Canis familiaris	84.81	0.00e+00	1179.00
IUUC-Cpo-021755	Cavia porcellus	80.19	0.00e+00	1246.00
IUUC-Csa-023814	Chlorocebus sabaeus	79.68	0.00e+00	1157.00
IUUC-Cho-024980	Choloepus hoffmanni	64.80	0.00e+00	953.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.88	1.00e-95	344.00
IUUC-Dre-028551	Danio rerio	72.88	0.00e+00	1116.00
IUUC-Dno-029497	Dasypus novemcinctus	79.86	0.00e+00	1135.00
IUUC-Dor-030867	Dipodomys ordii	69.96	0.00e+00	1028.00
IUUC-Dse-031239	Dothistroma septosporum	32.38	1.00e-90	328.00
IUUC-Ete-032902	Echinops telfairi	83.33	0.00e+00	1027.00
IUUC-Eca-033678	Equus caballus	80.55	0.00e+00	1244.00
IUUC-Eeu-035262	Erinaceus europaeus	68.08	0.00e+00	939.00
IUUC-Fca-035590	Felis catus	81.37	0.00e+00	1268.00
IUUC-Fal-037123	Ficedula albicollis	80.19	0.00e+00	1221.00
IUUC-Fox-037941	Fusarium oxysporum	39.84	5.00e-101	362.00
IUUC-Fso-038388	Fusarium solani	41.47	7.00e-104	372.00
IUUC-Gmo-039553	Gadus morhua	64.12	0.00e+00	828.00
IUUC-Ggr-040110	Gaeumannomyces graminis	32.71	3.00e-101	363.00
IUUC-Gga-040406	Gallus gallus	84.20	0.00e+00	1316.00
IUUC-Gac-042141	Gasterosteus aculeatus	73.62	0.00e+00	1085.00
IUUC-Ggo-045504	Gorilla gorilla	79.65	0.00e+00	1224.00
IUUC-Hsa-045786	Homo sapiens	79.95	0.00e+00	1227.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	77.33	0.00e+00	1097.00
IUUC-Kpa-049152	Komagataella pastoris	33.01	2.00e-77	283.00
IUUC-Lch-049824	Latimeria chalumnae	76.99	0.00e+00	1068.00
IUUC-Loc-052173	Lepisosteus oculatus	75.37	0.00e+00	1157.00
IUUC-Laf-054017	Loxodonta africana	82.68	0.00e+00	1204.00
IUUC-Mcc-055713	Macaca mulatta	79.92	0.00e+00	1204.00
IUUC-Meu-056212	Macropus eugenii	66.06	3.00e-108	385.00
IUUC-Mor-057045	Magnaporthe oryzae	35.83	2.00e-90	327.00
IUUC-Mla-059187	Melampsora laricipopulina	44.47	9.00e-91	327.00
IUUC-Mga-059884	Meleagris gallopavo	76.70	0.00e+00	1139.00
IUUC-Mmr-061344	Microcebus murinus	81.38	0.00e+00	1231.00
IUUC-Mdo-062653	Monodelphis domestica	80.32	0.00e+00	1219.00
IUUC-Mmu-063775	Mus musculus	80.93	0.00e+00	1172.00
IUUC-Mpu-066069	Mustela putorius furo	83.84	0.00e+00	1192.00
IUUC-Mlu-067925	Myotis lucifugus	80.96	0.00e+00	1229.00
IUUC-Nfi-068439	Neosartorya fischeri	33.66	4.00e-93	336.00
IUUC-Ncr-068903	Neurospora crassa	30.40	3.00e-95	343.00
IUUC-Nle-070046	Nomascus leucogenys	80.05	0.00e+00	1233.00
IUUC-Opr-071085	Ochotona princeps	75.17	5.00e-130	458.00
IUUC-Ont-072126	Oreochromis niloticus	71.16	0.00e+00	1120.00
IUUC-Oan-072933	Ornithorhynchus anatinus	83.18	0.00e+00	1128.00
IUUC-Ocu-073800	Oryctolagus cuniculus	84.29	0.00e+00	1178.00
IUUC-Ola-086988	Oryzias latipes	74.53	0.00e+00	1099.00
IUUC-Oga-088117	Otolemur garnettii	87.24	0.00e+00	1059.00
IUUC-Oar-089371	Ovis aries	81.64	0.00e+00	1237.00
IUUC-Ptr-090551	Pan troglodytes	79.75	0.00e+00	1197.00
IUUC-Pan-092067	Papio anubis	80.35	0.00e+00	1209.00
IUUC-Psi-092963	Pelodiscus sinensis	83.79	0.00e+00	1237.00
IUUC-Pfo-096562	Poecilia formosa	70.16	0.00e+00	1095.00
IUUC-Pab-098680	Pongo abelii	80.08	0.00e+00	1228.00
IUUC-Pca-100986	Procavia capensis	66.50	0.00e+00	811.00
IUUC-Pva-102219	Pteropus vampyrus	68.25	0.00e+00	941.00
IUUC-Pgr-103315	Puccinia graminis	35.71	1.00e-96	347.00
IUUC-Ptt-103736	Puccinia triticina	41.49	7.00e-96	345.00
IUUC-Rno-105270	Rattus norvegicus	80.55	0.00e+00	1169.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.71	3.00e-71	263.00
IUUC-Sha-106819	Sarcophilus harrisii	81.92	0.00e+00	1269.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.27	5.00e-84	305.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	39.12	7.00e-85	308.00
IUUC-Sar-113134	Sorex araneus	73.15	0.00e+00	1086.00
IUUC-Ssc-115441	Sus scrofa	81.23	0.00e+00	1234.00
IUUC-Tgu-117166	Taeniopygia guttata	82.61	0.00e+00	1244.00
IUUC-Tsy-118898	Tarsius syrichta	70.67	0.00e+00	994.00
IUUC-Tre-122108	Trichoderma reesei	37.60	1.00e-90	327.00
IUUC-Tvi-122644	Trichoderma virens	38.28	2.00e-95	344.00
IUUC-Tme-127004	Tuber melanosporum	34.09	4.00e-103	369.00
IUUC-Tbe-127292	Tupaia belangeri	65.62	0.00e+00	911.00
IUUC-Ttr-128352	Tursiops truncatus	77.40	0.00e+00	1172.00
IUUC-Vda-129969	Verticillium dahliae	39.34	1.00e-91	331.00
IUUC-Vpa-130218	Vicugna pacos	77.18	0.00e+00	873.00
IUUC-Xtr-132594	Xenopus tropicalis	75.20	0.00e+00	1123.00
IUUC-Xma-134157	Xiphophorus maculatus	72.22	0.00e+00	1009.00
IUUC-Yli-134470	Yarrowia lipolytica	31.56	7.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence