iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089633

Ensembl Protein ID

ENSOARP00000019481.1

UniProt Accession

W5Q9T8; W5Q9T8_SHEEP

Genbank Protein ID

ENSOARP00000019481

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01082114

Gene Name

FBXO7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018147.1	ENSOART00000019752.1	ENSOARP00000019481.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	79.51	0.00e+00	727.00	IUUC-Hsa-046348

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MKLRVRLQKR TWPLDMPEAE PTLGQLRAHL SQALLPTWGY SSDARFAITL NNKDALTGDE 60
ETLASYGIVS GDLICLILED AIAAPNLPSS TVSEHSSLQN NDQPSLAASS SQSSIQDAQL 120

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Nucleotide Sequence
(Fasta)

ATGAAGCTGC GGGTCCGGCT TCAGAAGCGG ACCTGGCCTC TGGATATGCC AGAAGCGGAG 60
CCGACTCTGG GGCAGCTGCG CGCGCACCTG AGCCAGGCCC TGCTGCCCAC CTGGGGGTAC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR021625--PI31_Prot_N

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF11566--PI31_Prot_N

Gene Ontology

GO:0097414--C:classical Lewy body
GO:0005829--C:cytosol
GO:0097409--C:glial cytoplasmic inclusion
GO:1990037--C:Lewy body core
GO:1990038--C:Lewy body corona
GO:0097462--C:Lewy neurite
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0000422--P:mitophagy
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:2000134--P:negative regulation of G1/S transition of mitotic cell cycle
GO:0045620--P:negative regulation of lymphocyte differentiation
GO:1903204--P:negative regulation of oxidative stress-induced neuron death
GO:1903599--P:positive regulation of mitophagy
GO:0006626--P:protein targeting to mitochondrion
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0040012--P:regulation of locomotion
GO:0010975--P:regulation of neuron projection development
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000290	Aegilops tauschii	22.62	2.00e-05	43.10
IUUC-Aml-001880	Ailuropoda melanoleuca	86.07	0.00e+00	652.00
IUUC-Atr-003003	Amborella trichopoda	26.81	2.00e-09	57.40
IUUC-Apl-003234	Anas platyrhynchos	64.42	2.00e-164	572.00
IUUC-Aca-004673	Anolis carolinensis	62.95	2.00e-154	538.00
IUUC-Ath-007055	Arabidopsis thaliana	24.83	4.00e-12	65.90
IUUC-Ang-009828	Aspergillus niger	33.96	4.50e-02	32.30
IUUC-Ame-011733	Astyanax mexicanus	43.04	3.00e-70	259.00
IUUC-Bta-013386	Bos taurus	95.83	0.00e+00	849.00
IUUC-Bdi-014029	Brachypodium distachyon	20.70	1.00e-06	47.80
IUUC-Bol-015733	Brassica oleracea	25.12	1.00e-14	74.30
IUUC-Bra-016639	Brassica rapa	26.50	6.00e-10	58.90
IUUC-Cja-019301	Callithrix jacchus	83.11	0.00e+00	818.00
IUUC-Cfa-020474	Canis familiaris	88.05	0.00e+00	787.00
IUUC-Cpo-021958	Cavia porcellus	74.10	0.00e+00	737.00
IUUC-Csa-023971	Chlorocebus sabaeus	82.73	0.00e+00	769.00
IUUC-Cho-024677	Choloepus hoffmanni	80.70	5.00e-122	430.00
IUUC-Cin-025781	Ciona intestinalis	28.71	4.00e-42	166.00
IUUC-Csv-025989	Ciona savignyi	27.30	1.00e-18	86.70
IUUC-Dre-027820	Danio rerio	43.98	8.00e-37	147.00
IUUC-Dno-029936	Dasypus novemcinctus	76.27	0.00e+00	714.00
IUUC-Dor-030716	Dipodomys ordii	80.25	0.00e+00	654.00
IUUC-Ete-032853	Echinops telfairi	63.99	7.00e-117	414.00
IUUC-Eca-034267	Equus caballus	88.71	0.00e+00	704.00
IUUC-Eeu-035344	Erinaceus europaeus	80.32	4.00e-104	371.00
IUUC-Fca-035849	Felis catus	85.82	0.00e+00	750.00
IUUC-Fal-037612	Ficedula albicollis	63.97	5.00e-152	530.00
IUUC-Gmo-039634	Gadus morhua	50.30	1.00e-20	93.60
IUUC-Gga-041190	Gallus gallus	63.91	2.00e-168	585.00
IUUC-Gac-042001	Gasterosteus aculeatus	47.60	7.00e-57	214.00
IUUC-Gma-044390	Glycine max	25.06	5.00e-07	49.30
IUUC-Ggo-044544	Gorilla gorilla	81.02	0.00e+00	749.00
IUUC-Hsa-046348	Homo sapiens	81.21	0.00e+00	751.00
IUUC-Itr-048160	Ictidomys tridecemlineatus	82.14	0.00e+00	678.00
IUUC-Lch-049937	Latimeria chalumnae	53.02	1.00e-109	390.00
IUUC-Loc-052097	Lepisosteus oculatus	44.08	6.00e-84	304.00
IUUC-Laf-053445	Loxodonta africana	80.27	0.00e+00	721.00
IUUC-Meu-055942	Macropus eugenii	62.63	2.00e-134	472.00
IUUC-Mga-059897	Meleagris gallopavo	65.32	9.00e-122	429.00
IUUC-Mmr-061491	Microcebus murinus	86.53	0.00e+00	780.00
IUUC-Mdo-062549	Monodelphis domestica	70.73	0.00e+00	677.00
IUUC-Mmu-064312	Mus musculus	73.43	0.00e+00	745.00
IUUC-Mac-064591	Musa acuminata	24.15	5.00e-07	48.90
IUUC-Mlu-067947	Myotis lucifugus	85.25	0.00e+00	683.00
IUUC-Nle-069189	Nomascus leucogenys	80.46	0.00e+00	740.00
IUUC-Opr-070340	Ochotona princeps	61.34	3.00e-61	229.00
IUUC-Ont-071633	Oreochromis niloticus	43.26	6.00e-85	307.00
IUUC-Oan-073153	Ornithorhynchus anatinus	68.29	1.00e-141	496.00
IUUC-Ocu-074367	Oryctolagus cuniculus	81.64	0.00e+00	639.00
IUUC-Oba-075835	Oryza barthii	21.45	5.00e-07	49.30
IUUC-Obr-076729	Oryza brachyantha	22.46	6.00e-08	52.00
IUUC-Ome-081758	Oryza meridionalis	21.74	2.00e-06	48.10
IUUC-Opu-083777	Oryza punctata	23.48	2.00e-07	51.60
IUUC-Oru-084872	Oryza rufipogon	23.26	1.00e-05	45.40
IUUC-Osa-086001	Oryza sativa	23.26	2.00e-06	47.00
IUUC-Ola-087349	Oryzias latipes	40.84	2.00e-62	233.00
IUUC-Oga-088097	Otolemur garnettii	85.01	0.00e+00	749.00
IUUC-Ptr-091253	Pan troglodytes	80.46	0.00e+00	743.00
IUUC-Pan-092709	Papio anubis	82.54	0.00e+00	768.00
IUUC-Pma-094225	Petromyzon marinus	35.48	5.00e-64	238.00
IUUC-Ppa-095848	Physcomitrella patens	23.99	6.00e-05	42.70
IUUC-Pfo-096303	Poecilia formosa	39.08	5.00e-58	218.00
IUUC-Pab-098160	Pongo abelii	81.89	0.00e+00	684.00
IUUC-Pop-099047	Populus trichocarpa	24.92	1.00e-11	64.70
IUUC-Pca-100918	Procavia capensis	77.22	2.00e-126	445.00
IUUC-Ppe-101570	Prunus persica	23.53	1.00e-05	44.30
IUUC-Pva-103142	Pteropus vampyrus	87.65	0.00e+00	725.00
IUUC-Rno-105527	Rattus norvegicus	73.06	0.00e+00	728.00
IUUC-Sha-106501	Sarcophilus harrisii	69.33	2.00e-164	572.00
IUUC-Smo-108975	Selaginella moellendorffii	26.29	9.00e-06	42.70
IUUC-Sly-111386	Solanum lycopersicum	25.49	1.00e-12	68.20
IUUC-Stu-112530	Solanum tuberosum	25.05	2.00e-19	90.50
IUUC-Sar-113529	Sorex araneus	84.39	0.00e+00	727.00
IUUC-Sbi-114203	Sorghum bicolor	20.93	3.00e-05	43.10
IUUC-Ssc-116130	Sus scrofa	90.70	0.00e+00	836.00
IUUC-Tgu-116850	Taeniopygia guttata	62.88	4.00e-152	531.00
IUUC-Tru-117759	Takifugu rubripes	39.17	2.00e-69	256.00
IUUC-Tni-120308	Tetraodon nigroviridis	38.32	1.00e-54	207.00
IUUC-Tca-120980	Theobroma cacao	22.61	4.00e-08	53.10
IUUC-Tae-123742	Triticum aestivum	22.69	3.00e-05	43.10
IUUC-Tbe-127805	Tupaia belangeri	72.04	1.00e-155	543.00
IUUC-Ttr-129004	Tursiops truncatus	90.33	0.00e+00	787.00
IUUC-Vpa-130452	Vicugna pacos	90.12	0.00e+00	736.00
IUUC-Vvi-131289	Vitis vinifera	25.07	7.00e-11	62.00
IUUC-Xtr-132447	Xenopus tropicalis	48.13	6.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence