iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089106

Ensembl Protein ID

ENSOGAP00000014255.2

UniProt Accession

H0XE95; H0XE95_OTOGA

Genbank Protein ID

ENSOGAP00000014255

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03078265

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015911.2	ENSOGAT00000015919.2	ENSOGAP00000014255.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/UBZ	62.01	0.00e+00	1385.00	IUUC-Hsa-047035

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

FSNHVGGLKR KVATNKKETQ KKQKVVEAPS EDLLVAMALS RSEMEQCPAV AELKLESAFS 60
ERVRPGAEKK SHKKKTLVPL PRLLVQDSET TGRQIEDQVA LLLSEEAEFS STPPLPASRI 120

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Nucleotide Sequence
(Fasta)

TTTAGCAATC ACGTGGGAGG TTTGAAACGG AAAGTAGCCA CTAACAAGAA GGAGACACAG 60
AAGAAGCAGA AGGTTGTCGA GGCACCCTCC GAGGACCTGC TGGTGGCCAT GGCGCTGTCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	59.64	0.00e+00	1207.00
IUUC-Apl-003261	Anas platyrhynchos	35.14	1.00e-109	391.00
IUUC-Aca-004455	Anolis carolinensis	70.18	1.00e-18	84.00
IUUC-Aor-010209	Aspergillus oryzae	55.56	3.20e-01	27.70
IUUC-Bta-013472	Bos taurus	53.88	0.00e+00	1002.00
IUUC-Cel-018663	Caenorhabditis elegans	38.64	5.00e-03	36.60
IUUC-Cja-019406	Callithrix jacchus	61.47	0.00e+00	1201.00
IUUC-Cfa-020129	Canis familiaris	57.73	0.00e+00	1033.00
IUUC-Cpo-021944	Cavia porcellus	56.20	0.00e+00	1144.00
IUUC-Csa-023941	Chlorocebus sabaeus	57.66	0.00e+00	755.00
IUUC-Cho-024847	Choloepus hoffmanni	57.86	2.00e-112	401.00
IUUC-Cin-025405	Ciona intestinalis	30.77	1.00e-12	67.00
IUUC-Csv-025916	Ciona savignyi	31.11	2.00e-06	46.20
IUUC-Dre-027764	Danio rerio	46.43	2.00e-39	158.00
IUUC-Dno-030083	Dasypus novemcinctus	51.25	0.00e+00	939.00
IUUC-Dor-031129	Dipodomys ordii	53.55	0.00e+00	905.00
IUUC-Ete-032536	Echinops telfairi	45.31	2.00e-126	447.00
IUUC-Eca-033407	Equus caballus	65.76	0.00e+00	1394.00
IUUC-Eeu-034473	Erinaceus europaeus	52.58	3.00e-30	128.00
IUUC-Fca-035730	Felis catus	58.07	0.00e+00	1185.00
IUUC-Fal-036850	Ficedula albicollis	34.38	1.00e-135	478.00
IUUC-Gmo-038677	Gadus morhua	42.67	2.00e-33	137.00
IUUC-Gga-041088	Gallus gallus	34.16	3.00e-126	447.00
IUUC-Gac-041824	Gasterosteus aculeatus	40.91	2.00e-13	68.90
IUUC-Ggo-045642	Gorilla gorilla	62.46	0.00e+00	1297.00
IUUC-Hsa-047035	Homo sapiens	62.04	0.00e+00	1303.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	61.00	0.00e+00	1222.00
IUUC-Kpa-049328	Komagataella pastoris	29.41	7.00e-04	39.30
IUUC-Lch-050364	Latimeria chalumnae	42.63	3.00e-77	284.00
IUUC-Loc-052423	Lepisosteus oculatus	41.00	2.00e-46	181.00
IUUC-Laf-053910	Loxodonta africana	57.92	0.00e+00	1164.00
IUUC-Mcc-055883	Macaca mulatta	63.03	0.00e+00	1364.00
IUUC-Meu-056224	Macropus eugenii	51.30	3.00e-90	327.00
IUUC-Mga-059880	Meleagris gallopavo	34.02	2.00e-127	450.00
IUUC-Mvi-060510	Microbotryum violaceum	31.34	8.00e-04	39.70
IUUC-Mmr-061715	Microcebus murinus	74.00	0.00e+00	1717.00
IUUC-Mdo-062426	Monodelphis domestica	43.23	0.00e+00	721.00
IUUC-Mmu-063947	Mus musculus	57.35	0.00e+00	1214.00
IUUC-Mpu-066184	Mustela putorius furo	65.34	7.00e-179	622.00
IUUC-Mlu-067533	Myotis lucifugus	62.11	0.00e+00	1268.00
IUUC-Nle-069204	Nomascus leucogenys	63.27	0.00e+00	1299.00
IUUC-Opr-070377	Ochotona princeps	65.79	2.00e-159	557.00
IUUC-Ont-072551	Oreochromis niloticus	32.44	2.00e-38	155.00
IUUC-Oan-073350	Ornithorhynchus anatinus	53.45	3.00e-42	166.00
IUUC-Ocu-074915	Oryctolagus cuniculus	55.77	0.00e+00	725.00
IUUC-Ola-087360	Oryzias latipes	44.81	3.00e-33	134.00
IUUC-Oar-089289	Ovis aries	55.15	6.00e-178	619.00
IUUC-Ptr-091469	Pan troglodytes	62.53	0.00e+00	1298.00
IUUC-Pan-091841	Papio anubis	62.78	0.00e+00	1367.00
IUUC-Psi-093842	Pelodiscus sinensis	45.64	3.00e-89	324.00
IUUC-Pma-094732	Petromyzon marinus	57.69	3.00e-09	54.70
IUUC-Pfo-097299	Poecilia formosa	37.44	1.00e-31	132.00
IUUC-Pab-098271	Pongo abelii	63.22	0.00e+00	1299.00
IUUC-Pca-100721	Procavia capensis	50.62	3.00e-157	550.00
IUUC-Pva-102276	Pteropus vampyrus	61.56	0.00e+00	1317.00
IUUC-Rno-105619	Rattus norvegicus	54.67	0.00e+00	1141.00
IUUC-Sha-106722	Sarcophilus harrisii	42.70	3.00e-150	526.00
IUUC-Sar-113673	Sorex araneus	58.60	3.00e-82	301.00
IUUC-Sre-115039	Sporisorium reilianum	35.85	5.00e-05	41.60
IUUC-Ssc-115383	Sus scrofa	57.03	0.00e+00	1037.00
IUUC-Tgu-117243	Taeniopygia guttata	50.38	2.00e-96	345.00
IUUC-Tru-118092	Takifugu rubripes	66.67	8.00e-20	90.50
IUUC-Tsy-119362	Tarsius syrichta	62.52	0.00e+00	662.00
IUUC-Tni-120380	Tetraodon nigroviridis	45.57	4.00e-13	68.20
IUUC-Tbe-127404	Tupaia belangeri	47.69	0.00e+00	735.00
IUUC-Ttr-128317	Tursiops truncatus	59.85	0.00e+00	1079.00
IUUC-Uma-129640	Ustilago maydis	37.29	2.00e-05	43.10
IUUC-Xtr-132533	Xenopus tropicalis	39.47	2.00e-56	215.00
IUUC-Xma-134059	Xiphophorus maculatus	36.03	5.00e-32	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence