iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066109

Ensembl Protein ID

ENSMPUP00000010859.1

UniProt Accession

M3YHQ2; M3YHQ2_MUSPF

Genbank Protein ID

ENSMPUP00000010859

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01078952

Gene Name

TNIP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010947.1	ENSMPUT00000011040.1	ENSMPUP00000010859.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.30e-18	66.7	295	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklnds 56
           ++++le+v++L+qQ+ +Yk+DF +ERadREr++ +++eL+e v++l +q s+ ++ 
   Q: 295  RDAALERVQMLEQQILAYKDDFTSERADRERAQGRIQELEEEVASLRQQASWTQER 350
           6899************************************************9976 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSTGGAGSGG QEGTARAAAA LCGLYHEAGQ RLRRLEDQLA ARDALIERLR ARLAAVEGDA 60
APSLVDALLE QVARFREQLR QREGGADEAA LRQEIERLSE QLEEKEKAAQ QLMSQPEHER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCTATGTG GCCAACCCGG CCTGCAGCGC CGGGATGTGG ACCCACGCAC AGGTCCAGCA 60
CTTGAGGTCG CCTTCACCCC TTCTTTCCCT CCCATCATCA CCTGCATCAG GGGCGGGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR015898--G-protein_gamma-like_dom
IPR034735--ZF_CCHC_NOA

PROSITE

PS50058--G_PROTEIN_GAMMA
PS51801--ZF_CCHC_NOA

Pfam

PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005834--C:heterotrimeric G-protein complex
GO:0005634--C:nucleus
GO:0004871--F:signal transducer activity
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	86.73	2.00e-167	581.00
IUUC-Apl-003896	Anas platyrhynchos	46.99	6.00e-94	337.00
IUUC-Ame-011223	Astyanax mexicanus	33.48	1.00e-47	184.00
IUUC-Bta-012996	Bos taurus	77.49	4.00e-138	483.00
IUUC-Cja-019376	Callithrix jacchus	71.39	5.00e-134	470.00
IUUC-Cfa-021027	Canis familiaris	82.07	0.00e+00	659.00
IUUC-Cpo-021372	Cavia porcellus	66.83	1.00e-112	399.00
IUUC-Csa-023221	Chlorocebus sabaeus	76.83	2.00e-150	525.00
IUUC-Dre-028604	Danio rerio	34.75	4.00e-57	215.00
IUUC-Dno-029976	Dasypus novemcinctus	65.91	3.00e-52	197.00
IUUC-Dor-030364	Dipodomys ordii	56.10	2.00e-58	219.00
IUUC-Eca-033582	Equus caballus	81.00	7.00e-161	559.00
IUUC-Eeu-034751	Erinaceus europaeus	64.98	8.00e-58	216.00
IUUC-Fca-036086	Felis catus	83.09	9.00e-146	509.00
IUUC-Fal-036828	Ficedula albicollis	47.72	5.00e-101	361.00
IUUC-Gmo-038838	Gadus morhua	36.77	2.00e-45	176.00
IUUC-Gga-041179	Gallus gallus	47.46	3.00e-96	345.00
IUUC-Gac-042266	Gasterosteus aculeatus	37.59	2.00e-49	189.00
IUUC-Ggo-044971	Gorilla gorilla	78.15	8.00e-152	530.00
IUUC-Hsa-045772	Homo sapiens	78.38	1.00e-145	509.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	72.01	1.00e-125	442.00
IUUC-Lch-049851	Latimeria chalumnae	41.10	4.00e-74	271.00
IUUC-Loc-052551	Lepisosteus oculatus	37.81	3.00e-65	242.00
IUUC-Laf-053650	Loxodonta africana	55.11	4.00e-84	304.00
IUUC-Mcc-054744	Macaca mulatta	76.83	2.00e-155	541.00
IUUC-Meu-056799	Macropus eugenii	49.34	4.00e-31	128.00
IUUC-Mga-060124	Meleagris gallopavo	45.07	1.00e-90	326.00
IUUC-Mmr-061466	Microcebus murinus	76.24	1.00e-135	476.00
IUUC-Mdo-062389	Monodelphis domestica	55.10	3.00e-114	405.00
IUUC-Mmu-064000	Mus musculus	69.46	6.00e-150	523.00
IUUC-Mlu-067666	Myotis lucifugus	66.94	1.00e-72	265.00
IUUC-Nle-069689	Nomascus leucogenys	75.23	6.00e-136	476.00
IUUC-Opr-070774	Ochotona princeps	58.59	5.00e-73	267.00
IUUC-Ont-072439	Oreochromis niloticus	38.36	8.00e-66	244.00
IUUC-Oan-072817	Ornithorhynchus anatinus	54.77	3.00e-61	228.00
IUUC-Ocu-074621	Oryctolagus cuniculus	66.19	1.00e-86	312.00
IUUC-Oba-075317	Oryza barthii	36.54	1.60e-01	30.40
IUUC-Olo-080222	Oryza longistaminata	37.50	2.00e+00	26.90
IUUC-Ola-087305	Oryzias latipes	37.47	4.00e-60	225.00
IUUC-Oga-087920	Otolemur garnettii	70.18	3.00e-132	464.00
IUUC-Oar-090351	Ovis aries	65.62	4.00e-20	89.00
IUUC-Ptr-090879	Pan troglodytes	74.90	3.00e-96	344.00
IUUC-Pan-092022	Papio anubis	77.07	7.00e-151	526.00
IUUC-Psi-093302	Pelodiscus sinensis	46.92	2.00e-107	382.00
IUUC-Pno-095083	Phaeosphaeria nodorum	28.99	2.00e-04	42.00
IUUC-Pfo-097250	Poecilia formosa	37.04	3.00e-56	212.00
IUUC-Pab-097929	Pongo abelii	75.84	7.00e-140	489.00
IUUC-Pca-100271	Procavia capensis	65.56	1.00e-39	157.00
IUUC-Pva-102234	Pteropus vampyrus	69.64	3.00e-119	421.00
IUUC-Rno-105850	Rattus norvegicus	71.90	7.00e-158	550.00
IUUC-Sha-107375	Sarcophilus harrisii	51.38	1.00e-100	360.00
IUUC-Ssc-116269	Sus scrofa	80.96	3.00e-158	551.00
IUUC-Tgu-116960	Taeniopygia guttata	49.44	2.00e-93	336.00
IUUC-Tru-118002	Takifugu rubripes	34.46	2.00e-54	206.00
IUUC-Tni-120023	Tetraodon nigroviridis	37.05	1.00e-56	213.00
IUUC-Tbe-127592	Tupaia belangeri	69.98	1.00e-143	502.00
IUUC-Ttr-128362	Tursiops truncatus	71.35	8.00e-121	426.00
IUUC-Vpa-130399	Vicugna pacos	73.39	1.00e-125	442.00
IUUC-Xtr-132677	Xenopus tropicalis	44.04	1.00e-87	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence