iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091049

UUCD1 version

UUC-PaT-00546

Ensembl Protein ID

ENSPTRP00000027433.3

UniProt Accession

H2QP88; H2QP88_PANTR

Genbank Protein ID

JAA18911.1; JAA24785.1; JAA35878.1

Protein Name

F-box and leucine-rich repeat protein 5

Genbank Nucleotide ID

AACZ03031949; GABD01008315; GABE01008861

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015927.4	ENSPTRT00000029732.3	ENSPTRP00000027433.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	99.71	0.00e+00	1361.00	IUUC-Hsa-047001

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAPFPEEVDV FTAPHWRMKQ LVGLYCDKLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI 60
ENEYIIGLLQ QRSQTIYNVH SDNKLSEMLS LFEKGLKNVK NEYEQLNYAK QLKERLEAFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGGGCGCG CGCGCCGAAC GGGCGGGCGC ATGCGCAAGG GGGCGCGCCG CCTCTGCCCC 60
GCGGCGAGGG TGTCTATGGA GAGGCGGCGG CCGCGGCTGC TGAGGCGGAG GCTGAGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR012312--Haemerythrin-like
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF01814--Hemerythrin
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	96.26	0.00e+00	1207.00
IUUC-Apl-003755	Anas platyrhynchos	79.82	0.00e+00	999.00
IUUC-Aca-004798	Anolis carolinensis	77.06	0.00e+00	1036.00
IUUC-Ame-011091	Astyanax mexicanus	60.00	0.00e+00	759.00
IUUC-Bta-013204	Bos taurus	94.16	0.00e+00	1210.00
IUUC-Cja-019594	Callithrix jacchus	97.17	0.00e+00	1053.00
IUUC-Cfa-020965	Canis familiaris	96.38	0.00e+00	1253.00
IUUC-Cpo-021308	Cavia porcellus	93.78	0.00e+00	1246.00
IUUC-Csa-023865	Chlorocebus sabaeus	98.84	0.00e+00	1347.00
IUUC-Cho-024778	Choloepus hoffmanni	82.66	8.00e-163	566.00
IUUC-Dre-027628	Danio rerio	54.39	2.00e-176	612.00
IUUC-Dno-029899	Dasypus novemcinctus	94.46	0.00e+00	1283.00
IUUC-Dor-031105	Dipodomys ordii	82.20	0.00e+00	1065.00
IUUC-Ete-032314	Echinops telfairi	87.18	0.00e+00	1088.00
IUUC-Eca-033797	Equus caballus	95.13	0.00e+00	1151.00
IUUC-Eeu-034811	Erinaceus europaeus	84.33	0.00e+00	880.00
IUUC-Fca-036516	Felis catus	95.63	0.00e+00	1187.00
IUUC-Fal-036824	Ficedula albicollis	77.71	0.00e+00	932.00
IUUC-Gga-040271	Gallus gallus	80.64	0.00e+00	1067.00
IUUC-Gac-041399	Gasterosteus aculeatus	62.36	0.00e+00	786.00
IUUC-Ggo-044415	Gorilla gorilla	99.71	0.00e+00	1353.00
IUUC-Hsa-047001	Homo sapiens	99.71	0.00e+00	1366.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	94.43	0.00e+00	1048.00
IUUC-Lch-049897	Latimeria chalumnae	65.62	0.00e+00	831.00
IUUC-Loc-052162	Lepisosteus oculatus	66.24	0.00e+00	855.00
IUUC-Laf-054031	Loxodonta africana	95.66	0.00e+00	1275.00
IUUC-Mcc-054680	Macaca mulatta	98.84	0.00e+00	1347.00
IUUC-Meu-056199	Macropus eugenii	85.46	1.00e-104	374.00
IUUC-Mga-059675	Meleagris gallopavo	80.00	0.00e+00	1019.00
IUUC-Mmr-061694	Microcebus murinus	96.96	0.00e+00	1317.00
IUUC-Mdo-062900	Monodelphis domestica	90.16	0.00e+00	1220.00
IUUC-Mmu-063178	Mus musculus	93.63	0.00e+00	1273.00
IUUC-Mpu-066584	Mustela putorius furo	95.95	0.00e+00	1258.00
IUUC-Mlu-067859	Myotis lucifugus	94.88	0.00e+00	1186.00
IUUC-Nle-069172	Nomascus leucogenys	99.42	0.00e+00	1326.00
IUUC-Opr-070992	Ochotona princeps	90.97	0.00e+00	1007.00
IUUC-Ont-072577	Oreochromis niloticus	61.06	0.00e+00	784.00
IUUC-Oan-072870	Ornithorhynchus anatinus	85.05	0.00e+00	909.00
IUUC-Ocu-074849	Oryctolagus cuniculus	93.05	0.00e+00	1244.00
IUUC-Ola-087146	Oryzias latipes	60.42	0.00e+00	774.00
IUUC-Oga-088307	Otolemur garnettii	95.51	0.00e+00	1242.00
IUUC-Oar-090192	Ovis aries	92.20	0.00e+00	1221.00
IUUC-Pan-091995	Papio anubis	98.99	0.00e+00	1350.00
IUUC-Psi-093154	Pelodiscus sinensis	79.91	0.00e+00	989.00
IUUC-Pma-094334	Petromyzon marinus	46.12	2.00e-137	482.00
IUUC-Pfo-096154	Poecilia formosa	61.07	0.00e+00	763.00
IUUC-Pab-098264	Pongo abelii	99.40	0.00e+00	1294.00
IUUC-Pca-100884	Procavia capensis	72.65	0.00e+00	932.00
IUUC-Pva-102114	Pteropus vampyrus	95.09	0.00e+00	1280.00
IUUC-Rno-105392	Rattus norvegicus	93.92	0.00e+00	1271.00
IUUC-Sha-106508	Sarcophilus harrisii	87.08	0.00e+00	1162.00
IUUC-Sar-113107	Sorex araneus	90.93	0.00e+00	832.00
IUUC-Ssc-115489	Sus scrofa	96.38	0.00e+00	1252.00
IUUC-Tgu-116734	Taeniopygia guttata	78.62	0.00e+00	1018.00
IUUC-Tru-117632	Takifugu rubripes	61.07	0.00e+00	773.00
IUUC-Tsy-119400	Tarsius syrichta	95.78	0.00e+00	1221.00
IUUC-Tni-120602	Tetraodon nigroviridis	59.97	0.00e+00	783.00
IUUC-Tbe-127833	Tupaia belangeri	94.48	0.00e+00	648.00
IUUC-Ttr-129289	Tursiops truncatus	95.63	0.00e+00	748.00
IUUC-Vpa-130253	Vicugna pacos	95.58	0.00e+00	636.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence