iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013547

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045478

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002698.4	ENSBTAT00000003493.4	ENSBTAP00000003493.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-113	380.0	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 871
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQKERE RAAVEIQAHI RSFLCRRRLQ REIRREIDEF 60
FKAEDSGSSK RSALCIFKIA RKLLFLFRIK EDNERFEKLC RCILSSMEAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGTTGG GACTCGTGCC AGGAGAGCTA TTAGCCCCTG GGGAGGGTGC CAGGGCTTTC 60
TGCCCTTTGC TCCTAAGCCC CTTTCCATGA GTGTTTTTTG TATCATGACT GACATCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

bta:512750

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.43	5.00e-106	379.00
IUUC-Aml-002107	Ailuropoda melanoleuca	96.44	0.00e+00	2079.00
IUUC-Atr-003017	Amborella trichopoda	38.30	3.00e-110	393.00
IUUC-Apl-003328	Anas platyrhynchos	89.36	0.00e+00	1854.00
IUUC-Aly-005794	Arabidopsis lyrata	38.93	2.00e-109	390.00
IUUC-Ath-007269	Arabidopsis thaliana	39.29	5.00e-112	399.00
IUUC-Bdi-014502	Brachypodium distachyon	38.97	8.00e-110	392.00
IUUC-Bol-015093	Brassica oleracea	40.00	2.00e-113	403.00
IUUC-Bra-016722	Brassica rapa	40.00	5.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	39.27	0.00e+00	678.00
IUUC-Cja-019855	Callithrix jacchus	96.07	0.00e+00	2068.00
IUUC-Cfa-020066	Canis familiaris	96.22	0.00e+00	2056.00
IUUC-Cpo-021504	Cavia porcellus	94.85	0.00e+00	2066.00
IUUC-Csa-023579	Chlorocebus sabaeus	95.79	0.00e+00	2068.00
IUUC-Cho-024430	Choloepus hoffmanni	86.00	0.00e+00	1555.00
IUUC-Cin-025750	Ciona intestinalis	47.25	0.00e+00	970.00
IUUC-Csv-026016	Ciona savignyi	47.95	0.00e+00	1012.00
IUUC-Dre-028271	Danio rerio	80.93	0.00e+00	1747.00
IUUC-Dno-029054	Dasypus novemcinctus	96.54	0.00e+00	2075.00
IUUC-Dor-030938	Dipodomys ordii	87.73	0.00e+00	1860.00
IUUC-Dme-031602	Drosophila melanogaster	47.69	0.00e+00	955.00
IUUC-Ete-033041	Echinops telfairi	76.28	0.00e+00	1350.00
IUUC-Eca-034411	Equus caballus	97.00	0.00e+00	2080.00
IUUC-Eeu-035201	Erinaceus europaeus	85.34	0.00e+00	810.00
IUUC-Fca-036594	Felis catus	95.51	0.00e+00	2058.00
IUUC-Fal-037317	Ficedula albicollis	84.48	0.00e+00	1850.00
IUUC-Gmo-039412	Gadus morhua	77.28	0.00e+00	1714.00
IUUC-Gga-040149	Gallus gallus	88.22	0.00e+00	1878.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.11	0.00e+00	1798.00
IUUC-Gma-043839	Glycine max	39.79	1.00e-111	397.00
IUUC-Ggo-045279	Gorilla gorilla	95.88	0.00e+00	2067.00
IUUC-Hsa-045660	Homo sapiens	95.60	0.00e+00	2061.00
IUUC-Hvu-047102	Hordeum vulgare	35.66	9.00e-106	378.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	93.28	0.00e+00	1042.00
IUUC-Lch-050664	Latimeria chalumnae	82.82	0.00e+00	1820.00
IUUC-Lpe-050755	Leersia perrieri	37.04	2.00e-98	354.00
IUUC-Loc-052791	Lepisosteus oculatus	83.05	0.00e+00	1789.00
IUUC-Laf-053902	Loxodonta africana	96.16	0.00e+00	2078.00
IUUC-Mcc-054730	Macaca mulatta	95.69	0.00e+00	2067.00
IUUC-Meu-056527	Macropus eugenii	79.66	0.00e+00	1663.00
IUUC-Mtr-057671	Medicago truncatula	39.79	6.00e-112	399.00
IUUC-Mga-059260	Meleagris gallopavo	87.78	0.00e+00	1875.00
IUUC-Mmr-060804	Microcebus murinus	94.39	0.00e+00	2011.00
IUUC-Mdo-062575	Monodelphis domestica	83.85	0.00e+00	1779.00
IUUC-Mmu-063636	Mus musculus	91.59	0.00e+00	1930.00
IUUC-Mac-064989	Musa acuminata	39.36	2.00e-107	384.00
IUUC-Mpu-066677	Mustela putorius furo	95.92	0.00e+00	1942.00
IUUC-Mlu-067952	Myotis lucifugus	95.32	0.00e+00	2003.00
IUUC-Nle-069153	Nomascus leucogenys	95.60	0.00e+00	2060.00
IUUC-Opr-070554	Ochotona princeps	93.97	0.00e+00	1877.00
IUUC-Ont-071372	Oreochromis niloticus	81.48	0.00e+00	1782.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.40	0.00e+00	741.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.77	0.00e+00	2029.00
IUUC-Oba-075006	Oryza barthii	36.13	2.00e-108	387.00
IUUC-Obr-076320	Oryza brachyantha	39.25	2.00e-109	390.00
IUUC-Ogl-077093	Oryza glaberrima	38.92	3.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	36.33	1.00e-108	387.00
IUUC-Oin-080058	Oryza indica	38.92	4.00e-109	389.00
IUUC-Olo-080475	Oryza longistaminata	36.39	1.00e-108	387.00
IUUC-Ome-081741	Oryza meridionalis	34.33	6.00e-102	365.00
IUUC-Oni-082385	Oryza nivara	36.33	1.00e-108	387.00
IUUC-Opu-083529	Oryza punctata	38.82	4.00e-109	389.00
IUUC-Oru-085128	Oryza rufipogon	37.18	1.00e-95	344.00
IUUC-Osa-085557	Oryza sativa	39.18	1.00e-108	387.00
IUUC-Ola-087337	Oryzias latipes	80.92	0.00e+00	1723.00
IUUC-Oga-088342	Otolemur garnettii	95.51	0.00e+00	1990.00
IUUC-Oar-090234	Ovis aries	98.68	0.00e+00	2128.00
IUUC-Ptr-091661	Pan troglodytes	95.88	0.00e+00	2065.00
IUUC-Pan-092728	Papio anubis	95.51	0.00e+00	2061.00
IUUC-Psi-093251	Pelodiscus sinensis	87.79	0.00e+00	1744.00
IUUC-Pma-094195	Petromyzon marinus	70.30	0.00e+00	1452.00
IUUC-Ppa-095544	Physcomitrella patens	38.03	1.00e-110	394.00
IUUC-Pfo-097472	Poecilia formosa	81.01	0.00e+00	1788.00
IUUC-Pab-098570	Pongo abelii	95.79	0.00e+00	2065.00
IUUC-Pca-100110	Procavia capensis	83.90	0.00e+00	1752.00
IUUC-Ppe-101281	Prunus persica	39.01	2.00e-107	384.00
IUUC-Pva-102887	Pteropus vampyrus	91.30	0.00e+00	1932.00
IUUC-Rno-106028	Rattus norvegicus	88.70	0.00e+00	1831.00
IUUC-Sha-107331	Sarcophilus harrisii	85.07	0.00e+00	1802.00
IUUC-Smo-109488	Selaginella moellendorffii	36.96	5.00e-106	379.00
IUUC-Sit-109811	Setaria italica	35.19	2.00e-110	393.00
IUUC-Sar-113287	Sorex araneus	86.18	0.00e+00	730.00
IUUC-Sbi-114433	Sorghum bicolor	34.81	1.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	97.01	0.00e+00	2081.00
IUUC-Tgu-117275	Taeniopygia guttata	87.85	0.00e+00	1865.00
IUUC-Tru-118681	Takifugu rubripes	79.98	0.00e+00	1797.00
IUUC-Tsy-118985	Tarsius syrichta	90.69	0.00e+00	1015.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.48	0.00e+00	778.00
IUUC-Tca-121770	Theobroma cacao	39.18	7.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.19	3.00e-106	380.00
IUUC-Tur-126086	Triticum urartu	39.43	1.00e-105	377.00
IUUC-Tbe-127461	Tupaia belangeri	91.29	0.00e+00	1904.00
IUUC-Ttr-129269	Tursiops truncatus	96.54	0.00e+00	2067.00
IUUC-Vpa-130523	Vicugna pacos	78.59	2.00e-131	463.00
IUUC-Vvi-131524	Vitis vinifera	39.04	2.00e-109	390.00
IUUC-Xtr-132146	Xenopus tropicalis	83.96	0.00e+00	1831.00
IUUC-Xma-133526	Xiphophorus maculatus	80.82	0.00e+00	1786.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence