iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106483

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01004019

Gene Name

MARCH5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000018432.1	ENSSHAT00000021943.1	ENSSHAP00000021768.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.40e-12	46.2	14	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCek..CrewfHpaClklsveeelpnsek..wiCpkCrs 53
           ++C+vC++++ed++   ++  C++  +++w+H+aCl+++v+e+++++++  ++Cp+C++
   Q: 14   RSCWVCFATDEDDRtaeWVRPCRCrgSTKWVHQACLQRWVDEKQRGNSTarVACPQCNA 72
           68***********7778******999*********************9999******97 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MGQCKCRQMY QISRSCWVCF ATDEDDRTAE WVRPCRCRGS TKWVHQACLQ RWVDEKQRGN 60
STARVACPQC NAEYLIVFPK LGPVVYVLDL ADRLISKACP FAAAGIMVGS IYWTAVTYGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACAAT GCAAATGCAG GCAGATGTAG TAAATGATAT TAAATGTTTG AATTGAAATA 60
GTTCACTACA GGAGCATAAA TTTTGTTTCA TTGTGTTGTT AATTTTTTAA CTCTATATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033275--MARCH-like
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090344--P:negative regulation of cell aging
GO:0090141--P:positive regulation of mitochondrial fission
GO:0051865--P:protein autoubiquitination
GO:0070585--P:protein localization to mitochondrion
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002055	Ailuropoda melanoleuca	99.63	2.00e-159	554.00
IUUC-Apl-004106	Anas platyrhynchos	99.25	2.00e-157	547.00
IUUC-Aca-004615	Anolis carolinensis	97.78	2.00e-157	547.00
IUUC-Acl-008017	Aspergillus clavatus	26.47	4.00e-10	59.70
IUUC-Afl-008538	Aspergillus flavus	22.22	2.00e-05	43.50
IUUC-Afu-008855	Aspergillus fumigatus	24.81	2.00e-10	60.50
IUUC-Ang-009850	Aspergillus niger	24.24	4.00e-09	55.80
IUUC-Ate-010339	Aspergillus terreus	26.25	2.00e-11	63.50
IUUC-Ame-011363	Astyanax mexicanus	98.51	4.00e-159	553.00
IUUC-Bgr-012038	Blumeria graminis	31.50	8.00e-08	51.60
IUUC-Bta-013194	Bos taurus	100.00	3.00e-159	553.00
IUUC-Bci-013963	Botrytis cinerea	25.83	5.00e-08	52.40
IUUC-Bdi-014566	Brachypodium distachyon	43.06	9.00e-09	53.50
IUUC-Cel-018634	Caenorhabditis elegans	40.62	2.00e-09	55.50
IUUC-Cja-019097	Callithrix jacchus	97.77	2.00e-157	547.00
IUUC-Cfa-020404	Canis familiaris	98.51	3.00e-158	550.00
IUUC-Cpo-022094	Cavia porcellus	99.26	1.00e-159	555.00
IUUC-Csa-023955	Chlorocebus sabaeus	99.26	1.00e-159	555.00
IUUC-Cho-024819	Choloepus hoffmanni	94.98	1.00e-118	418.00
IUUC-Cin-025730	Ciona intestinalis	59.71	6.00e-99	353.00
IUUC-Csv-025975	Ciona savignyi	59.26	7.00e-98	350.00
IUUC-Dre-027676	Danio rerio	97.77	5.00e-158	549.00
IUUC-Dno-029876	Dasypus novemcinctus	98.88	2.00e-159	554.00
IUUC-Dor-030204	Dipodomys ordii	95.96	3.00e-106	377.00
IUUC-Dse-031226	Dothistroma septosporum	26.37	2.00e-10	60.10
IUUC-Dme-031751	Drosophila melanogaster	53.68	5.00e-83	300.00
IUUC-Ete-032941	Echinops telfairi	99.26	1.00e-159	555.00
IUUC-Eca-033559	Equus caballus	99.26	1.00e-159	555.00
IUUC-Eeu-034761	Erinaceus europaeus	97.37	1.00e-153	534.00
IUUC-Fca-035951	Felis catus	99.26	1.00e-159	555.00
IUUC-Fal-036756	Ficedula albicollis	98.51	1.00e-158	551.00
IUUC-Fox-037934	Fusarium oxysporum	28.46	2.00e-07	50.80
IUUC-Fso-038122	Fusarium solani	26.35	8.00e-09	55.10
IUUC-Gmo-038695	Gadus morhua	93.23	2.00e-147	514.00
IUUC-Gga-040911	Gallus gallus	98.51	1.00e-158	551.00
IUUC-Gac-042449	Gasterosteus aculeatus	96.25	7.00e-154	535.00
IUUC-Ggo-045555	Gorilla gorilla	99.26	1.00e-159	555.00
IUUC-Hsa-046302	Homo sapiens	99.26	1.00e-159	555.00
IUUC-Itr-048942	Ictidomys tridecemlineatus	99.26	1.00e-159	555.00
IUUC-Kpa-049406	Komagataella pastoris	22.22	9.00e-03	34.70
IUUC-Lch-050077	Latimeria chalumnae	97.38	8.00e-157	545.00
IUUC-Loc-052045	Lepisosteus oculatus	98.88	2.00e-159	554.00
IUUC-Lma-053141	Leptosphaeria maculans	25.71	3.00e-08	53.50
IUUC-Laf-053982	Loxodonta africana	98.88	1.00e-157	548.00
IUUC-Mcc-055278	Macaca mulatta	99.26	1.00e-159	555.00
IUUC-Meu-056185	Macropus eugenii	99.25	4.00e-157	546.00
IUUC-Mor-057070	Magnaporthe oryzae	26.04	2.00e-07	50.40
IUUC-Mpo-057293	Magnaporthe poae	23.97	2.00e-05	43.90
IUUC-Mla-059023	Melampsora laricipopulina	25.19	2.00e-06	47.40
IUUC-Mga-060064	Meleagris gallopavo	97.06	2.00e-156	544.00
IUUC-Mvi-060427	Microbotryum violaceum	27.97	8.00e-07	48.90
IUUC-Mmr-060872	Microcebus murinus	99.26	1.00e-159	555.00
IUUC-Mdo-062907	Monodelphis domestica	99.26	1.00e-159	555.00
IUUC-Mmu-063792	Mus musculus	99.26	1.00e-159	555.00
IUUC-Mpu-065948	Mustela putorius furo	99.26	9.00e-160	555.00
IUUC-Mlu-067399	Myotis lucifugus	100.00	2.00e-159	553.00
IUUC-Nfi-068312	Neosartorya fischeri	25.00	2.00e-10	60.10
IUUC-Ncr-068837	Neurospora crassa	30.83	5.00e-12	66.20
IUUC-Nle-069197	Nomascus leucogenys	99.26	1.00e-159	555.00
IUUC-Opr-070474	Ochotona princeps	92.19	3.00e-145	507.00
IUUC-Ont-071896	Oreochromis niloticus	47.41	9.00e-73	266.00
IUUC-Oan-073425	Ornithorhynchus anatinus	98.51	7.00e-159	552.00
IUUC-Ocu-074127	Oryctolagus cuniculus	99.26	1.00e-159	555.00
IUUC-Ola-086561	Oryzias latipes	98.50	1.00e-156	544.00
IUUC-Oga-089004	Otolemur garnettii	97.10	2.00e-160	557.00
IUUC-Oar-089485	Ovis aries	99.26	3.00e-159	553.00
IUUC-Ptr-091645	Pan troglodytes	99.26	1.00e-159	555.00
IUUC-Pan-092408	Papio anubis	99.26	1.00e-159	555.00
IUUC-Psi-093325	Pelodiscus sinensis	93.31	4.00e-148	516.00
IUUC-Pma-094495	Petromyzon marinus	85.00	5.00e-87	313.00
IUUC-Pno-094820	Phaeosphaeria nodorum	26.40	2.00e-08	53.50
IUUC-Pfo-097381	Poecilia formosa	96.67	3.00e-156	543.00
IUUC-Pab-097888	Pongo abelii	99.26	1.00e-159	555.00
IUUC-Pva-102265	Pteropus vampyrus	99.26	1.00e-159	555.00
IUUC-Pgr-103326	Puccinia graminis	23.94	2.40e-02	33.90
IUUC-Pte-104347	Pyrenophora teres	26.97	8.00e-10	58.50
IUUC-Pyt-104598	Pyrenophora triticirepentis	38.00	7.00e-07	47.80
IUUC-Rno-105983	Rattus norvegicus	99.26	1.00e-159	555.00
IUUC-Sja-107897	Schizosaccharomyces japonicus	28.05	4.00e-05	42.40
IUUC-Spo-108227	Schizosaccharomyces pombe	28.30	3.00e-05	42.40
IUUC-Sar-113087	Sorex araneus	96.24	7.00e-152	528.00
IUUC-Sre-114892	Sporisorium reilianum	27.11	3.00e-14	73.20
IUUC-Ssc-115964	Sus scrofa	99.63	5.00e-160	556.00
IUUC-Tgu-117325	Taeniopygia guttata	99.25	5.00e-158	549.00
IUUC-Tru-118291	Takifugu rubripes	97.79	4.00e-105	372.00
IUUC-Tsy-119454	Tarsius syrichta	83.08	5.00e-127	446.00
IUUC-Tni-119754	Tetraodon nigroviridis	95.85	3.00e-148	517.00
IUUC-Tre-122138	Trichoderma reesei	32.52	2.00e-08	53.90
IUUC-Tvi-122629	Trichoderma virens	31.97	6.00e-09	55.50
IUUC-Tbe-127988	Tupaia belangeri	99.13	4.00e-136	476.00
IUUC-Ttr-128413	Tursiops truncatus	100.00	1.00e-135	474.00
IUUC-Uma-129544	Ustilago maydis	27.33	4.00e-16	79.30
IUUC-Vda-129998	Verticillium dahliae	29.57	2.00e-07	50.10
IUUC-Vpa-130036	Vicugna pacos	95.91	1.00e-153	535.00
IUUC-Xtr-131932	Xenopus tropicalis	95.59	2.00e-154	537.00
IUUC-Xma-134072	Xiphophorus maculatus	96.67	3.00e-156	543.00
IUUC-Zma-135012	Zea mays	46.51	1.00e-07	47.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence