iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069724

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01026009

Gene Name

VHL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000004411.2	ENSNLET00000005618.2	ENSNLEP00000005340.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	26.72	8.00e-04	40.80	IUUC-Dme-031988
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	98.59	2.00e-89	325.00	IUUC-Hsa-046547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPRRAENWDE AEVGAEEAGA EEYGPEEDGG EELGAEESGP EESGPEELGA EEEMEAGRPR 60
PVLRSVNSRE PSQVIFCNRS PRVVLPVWLN FDGEPQPYPT LPPGTGRRIH SYRGHLWLFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGGCCCG CGAATCCCGC GGCGTCCGGC CCGGGTGGTC TGGGCCGCGG CGGGAATGCC 60
CCGGAGGGCG GAGAACTGGG ACGAGGCCGA AGTAGGCGCG GAGGAGGCAG GCGCCGAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0061428--P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

nle:100600696

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002327	Ailuropoda melanoleuca	84.52	2.00e-69	254.00
IUUC-Apl-003580	Anas platyrhynchos	71.05	6.00e-26	107.00
IUUC-Aca-004492	Anolis carolinensis	78.74	4.00e-57	213.00
IUUC-Ang-009806	Aspergillus niger	40.62	1.10e-01	27.30
IUUC-Ame-011818	Astyanax mexicanus	46.31	1.00e-45	176.00
IUUC-Bta-013459	Bos taurus	94.90	3.00e-85	307.00
IUUC-Cel-018173	Caenorhabditis elegans	31.87	7.00e-05	40.00
IUUC-Cja-019826	Callithrix jacchus	98.09	1.00e-87	315.00
IUUC-Cfa-021280	Canis familiaris	95.45	8.00e-84	302.00
IUUC-Cpo-022544	Cavia porcellus	86.59	5.00e-85	306.00
IUUC-Cre-022809	Chlamydomonas reinhardtii	42.42	3.00e-08	53.10
IUUC-Csa-023644	Chlorocebus sabaeus	98.10	2.00e-89	321.00
IUUC-Cho-024479	Choloepus hoffmanni	65.15	7.00e-42	162.00
IUUC-Cin-025505	Ciona intestinalis	27.35	1.00e-05	42.00
IUUC-Cme-027232	Cyanidioschyzon merolae	33.78	9.00e-06	43.50
IUUC-Dre-028350	Danio rerio	53.42	3.00e-33	134.00
IUUC-Dno-029207	Dasypus novemcinctus	87.96	5.00e-52	196.00
IUUC-Dor-030912	Dipodomys ordii	67.11	3.00e-51	194.00
IUUC-Dme-031988	Drosophila melanogaster	26.72	1.00e-05	42.40
IUUC-Eca-034007	Equus caballus	97.50	8.00e-19	84.30
IUUC-Fca-036350	Felis catus	94.87	5.00e-83	300.00
IUUC-Fal-037192	Ficedula albicollis	69.13	1.00e-55	208.00
IUUC-Gmo-038921	Gadus morhua	57.72	4.00e-44	170.00
IUUC-Gga-041016	Gallus gallus	69.72	6.00e-55	206.00
IUUC-Gac-042560	Gasterosteus aculeatus	51.05	9.00e-36	142.00
IUUC-Ggo-045419	Gorilla gorilla	97.65	2.00e-89	321.00
IUUC-Hsa-046547	Homo sapiens	98.59	6.00e-90	323.00
IUUC-Itr-048225	Ictidomys tridecemlineatus	96.15	4.00e-86	309.00
IUUC-Lch-050463	Latimeria chalumnae	65.10	5.00e-54	203.00
IUUC-Loc-052053	Lepisosteus oculatus	57.34	1.00e-47	181.00
IUUC-Laf-053893	Loxodonta africana	92.41	1.00e-83	301.00
IUUC-Mcc-055347	Macaca mulatta	64.95	6.00e-65	239.00
IUUC-Mtr-058490	Medicago truncatula	48.48	7.00e-03	33.90
IUUC-Mdo-062169	Monodelphis domestica	75.53	3.00e-38	149.00
IUUC-Mmu-064366	Mus musculus	94.96	6.00e-76	276.00
IUUC-Mpu-066593	Mustela putorius furo	94.23	2.00e-84	304.00
IUUC-Mlu-066926	Myotis lucifugus	89.78	1.00e-87	315.00
IUUC-Opr-070679	Ochotona princeps	78.41	6.00e-76	275.00
IUUC-Ont-071332	Oreochromis niloticus	53.38	4.00e-42	163.00
IUUC-Ola-086869	Oryzias latipes	50.00	1.00e-39	155.00
IUUC-Oga-089124	Otolemur garnettii	95.60	2.00e-85	307.00
IUUC-Oar-089799	Ovis aries	91.92	3.00e-50	189.00
IUUC-Ptr-091186	Pan troglodytes	98.02	4.00e-54	202.00
IUUC-Pan-092150	Papio anubis	96.24	3.00e-88	317.00
IUUC-Psi-094039	Pelodiscus sinensis	67.14	6.00e-52	196.00
IUUC-Pma-094129	Petromyzon marinus	45.45	8.00e-28	116.00
IUUC-Pfo-096892	Poecilia formosa	50.35	5.00e-37	146.00
IUUC-Pab-097822	Pongo abelii	98.59	1.00e-90	325.00
IUUC-Pca-101058	Procavia capensis	82.33	6.00e-80	289.00
IUUC-Pva-102932	Pteropus vampyrus	97.47	2.00e-88	317.00
IUUC-Rno-105050	Rattus norvegicus	93.67	1.00e-86	311.00
IUUC-Sha-106738	Sarcophilus harrisii	78.00	4.00e-43	165.00
IUUC-Ssc-115973	Sus scrofa	92.99	5.00e-84	303.00
IUUC-Tgu-116663	Taeniopygia guttata	72.53	2.00e-33	132.00
IUUC-Tru-118654	Takifugu rubripes	56.64	9.00e-43	165.00
IUUC-Tca-121306	Theobroma cacao	38.89	3.50e-02	29.60
IUUC-Ttr-128418	Tursiops truncatus	94.94	2.00e-86	311.00
IUUC-Vpa-130268	Vicugna pacos	90.91	3.00e-48	184.00
IUUC-Xtr-132506	Xenopus tropicalis	62.75	4.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence