iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035664

Ensembl Protein ID

ENSFCAP00000002450.3

UniProt Accession

M3VYX2; M3VYX2_FELCA

Genbank Protein ID

ENSFCAP00000002450

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02044211

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000002658.3	ENSFCAT00000002663.3	ENSFCAP00000002450.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.20e-06	28.4	968	997

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 9    qlveMGFdreealqaLraannnleaAveyL 38
           q++  G ++ee++ aL+++++++++A+ yL
   Q: 968  QAMVHGVTTEECQAALQSHSWSVQRAAQYL 997
           56667**********************998 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAMC KRKSWMSKVF SGKRLEAEFP PHHSQSTFRK TSPTPGGPAG EGPLQSLTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAGCCCA CGCAGGCTGC TGCAGCAGCC CGAGCCGCTC TCCGAGTTCG GGGACCGTTC 60
CTGGGAGCGC GGGGAGGGGC TCGAAAGTTC CGGGGAGCCG GGGGCTCAGC ACTGGGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0042127--P:regulation of cell proliferation
GO:2000369--P:regulation of clathrin-dependent endocytosis
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	94.99	0.00e+00	1717.00
IUUC-Aca-004315	Anolis carolinensis	88.97	1.00e-73	268.00
IUUC-Ame-011350	Astyanax mexicanus	54.28	0.00e+00	1048.00
IUUC-Bta-012325	Bos taurus	96.07	0.00e+00	1773.00
IUUC-Cel-018130	Caenorhabditis elegans	36.77	1.00e-89	325.00
IUUC-Cja-019545	Callithrix jacchus	88.54	0.00e+00	1576.00
IUUC-Cfa-020706	Canis familiaris	97.98	0.00e+00	1812.00
IUUC-Cpo-022032	Cavia porcellus	88.64	0.00e+00	1667.00
IUUC-Csa-023936	Chlorocebus sabaeus	94.23	0.00e+00	1719.00
IUUC-Csv-026328	Ciona savignyi	59.04	8.00e-173	599.00
IUUC-Dre-028714	Danio rerio	63.50	0.00e+00	1238.00
IUUC-Dno-029525	Dasypus novemcinctus	95.11	0.00e+00	1751.00
IUUC-Dme-031778	Drosophila melanogaster	55.90	3.00e-144	506.00
IUUC-Ete-032225	Echinops telfairi	91.50	0.00e+00	867.00
IUUC-Gmo-039543	Gadus morhua	58.87	0.00e+00	951.00
IUUC-Gga-040241	Gallus gallus	69.25	0.00e+00	1323.00
IUUC-Gac-041457	Gasterosteus aculeatus	61.63	0.00e+00	1140.00
IUUC-Ggo-045333	Gorilla gorilla	91.58	0.00e+00	1692.00
IUUC-Hsa-046670	Homo sapiens	94.91	0.00e+00	1688.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	93.75	0.00e+00	1765.00
IUUC-Lch-049670	Latimeria chalumnae	61.85	0.00e+00	1199.00
IUUC-Loc-052870	Lepisosteus oculatus	63.86	0.00e+00	1278.00
IUUC-Laf-053782	Loxodonta africana	91.86	0.00e+00	1698.00
IUUC-Mcc-055874	Macaca mulatta	94.41	0.00e+00	1712.00
IUUC-Mga-059717	Meleagris gallopavo	70.15	0.00e+00	1373.00
IUUC-Mdo-062270	Monodelphis domestica	86.29	0.00e+00	1622.00
IUUC-Mmu-063861	Mus musculus	93.28	0.00e+00	1789.00
IUUC-Mpu-066127	Mustela putorius furo	96.59	0.00e+00	1396.00
IUUC-Mlu-067937	Myotis lucifugus	94.94	0.00e+00	1370.00
IUUC-Nle-069298	Nomascus leucogenys	94.49	0.00e+00	1409.00
IUUC-Ont-072437	Oreochromis niloticus	60.19	0.00e+00	1221.00
IUUC-Oan-073708	Ornithorhynchus anatinus	70.99	1.00e-111	396.00
IUUC-Ola-087023	Oryzias latipes	62.36	0.00e+00	1160.00
IUUC-Pan-091857	Papio anubis	94.25	3.00e-94	337.00
IUUC-Psi-093401	Pelodiscus sinensis	54.95	5.00e-149	521.00
IUUC-Pfo-097455	Poecilia formosa	59.36	0.00e+00	1209.00
IUUC-Rno-105586	Rattus norvegicus	92.90	0.00e+00	1761.00
IUUC-Sha-106868	Sarcophilus harrisii	90.81	0.00e+00	1305.00
IUUC-Ssc-116250	Sus scrofa	95.59	0.00e+00	1699.00
IUUC-Tgu-116592	Taeniopygia guttata	69.44	0.00e+00	1316.00
IUUC-Tru-117852	Takifugu rubripes	70.68	0.00e+00	628.00
IUUC-Tsy-119087	Tarsius syrichta	98.51	2.00e-158	553.00
IUUC-Tni-120826	Tetraodon nigroviridis	62.77	0.00e+00	1233.00
IUUC-Xtr-132069	Xenopus tropicalis	65.89	0.00e+00	1177.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence