iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-003044

Ensembl Protein ID

ERN19240

UniProt Accession

U5DAJ3; U5DAJ3_AMBTC

Genbank Protein ID

ERN19240.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KI392075

Gene Name

AMTR_s00061p00204480

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00061p00204480	ERN19240	ERN19240

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-120	403.1	3440	3779
UBD/Alpha-Helix/UBA	6.70e-06	26.5	1296	1329

Active Site

Position(s)	Description	Evidence
3747	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
            +dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf ++ ++++t+qpnp+s ++ +ehl++F+f+Gr+++kal+dg+lld+ +++sfyk++
   Q: 3440 SQDLKGRLTVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF-TTVGNNTTFQPNPNSVYQ-TEHLSYFKFVGRVVAKALFDGHLLDVYFTRSFYKHI 3536
           689************************************9999.566688899******986.5*********************************** PP
   S: 101  lgkklsledleevdpelykslkeikenaesdieelgldltfsvseei...lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreG 196
           lg+k++++d+e+vdp++yk+lk+++en+ sdi +l++ +  +++++i    +e++++eL+pgG+ni+Vt+e k+eYv+lv+e+rl++ i+ q+++f eG
   Q: 3537 LGVKVTYHDIEAVDPDFYKNLKWMLENDVSDIPDLTFSMDADEEKHIlygKSEVTDYELIPGGRNIRVTEETKHEYVDLVAEHRLTTAIRPQINSFLEG 3635
           ***************************7777777655555554444485555677888***************************************** PP
   S: 197  fneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk 291
           fne+ip+el+slF+ +elelli+G +eid++dlk++++y +gyt+ s++iqwFwev++ f++e+ +++LqFvTg+s++Pl Gf++l+    p+ f+i+k
   Q: 3636 FNELIPKELISLFNDKELELLISGLPEIDLDDLKANAEY-SGYTAVSSVIQWFWEVVKTFNKEDMARLLQFVTGTSKVPLDGFKDLQgisgPQHFQIHK 3733
           ***************************************.55********************************************************* PP
   S: 292  .dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
            +++++rlP+++TCfn+L+LPeYsske+l+e+Ll+A++e+ +gF++
   Q: 3734 aYGAPERLPTAHTCFNQLDLPEYSSKEQLQERLLLAVHEAsEGFGF 3779
           99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 9    qlveMGFdreealqaLraa.nnnleaAveyLldg 41
            +veMGF+r +a +aLr+    ++e+A+++L ++
   Q: 1296 TIVEMGFTRARAEEALRRVeTTSVEMAMDWLVSH 1329
           689***************66***********987 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

MIFKPPKIRA FINSVTSTPL EEIEKPLKSF TWEFDKGDFH HWVDLFNHFD SFFEKYIVPR 60
KDLQVGDNFL DVDPPFPREA VLQILRAIRI ILQKCTNKHF YSSYERHLSY LLASADADVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTTTCA AAGTTATATC TCATAGATAC ATATGATTAC TTCTTTTATT TAATAGTTAT 60
TGTAATTTTT TTTCAGCCTC CCAAAATTCG TGCCTTCATC AACAGTGTAA CATCTACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00185--ARM
SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	52.69	3.00e-126	447.00
IUUC-Aca-005263	Anolis carolinensis	52.93	6.00e-127	449.00
IUUC-Aly-006083	Arabidopsis lyrata	54.33	0.00e+00	2260.00
IUUC-Ath-007472	Arabidopsis thaliana	56.90	0.00e+00	3642.00
IUUC-Ago-008005	Ashbya gossypii	38.17	3.00e-129	457.00
IUUC-Acl-008254	Aspergillus clavatus	39.94	7.00e-141	495.00
IUUC-Afl-008712	Aspergillus flavus	40.92	9.00e-143	499.00
IUUC-Afu-009022	Aspergillus fumigatus	38.55	5.00e-140	493.00
IUUC-Ani-009412	Aspergillus nidulans	41.00	2.00e-144	507.00
IUUC-Ang-009771	Aspergillus niger	39.94	7.00e-141	495.00
IUUC-Aor-010186	Aspergillus oryzae	39.56	9.00e-133	467.00
IUUC-Ate-010253	Aspergillus terreus	39.47	7.00e-141	495.00
IUUC-Bta-012813	Bos taurus	52.69	5.00e-126	446.00
IUUC-Bra-016637	Brassica rapa	53.52	0.00e+00	3327.00
IUUC-Cel-018179	Caenorhabditis elegans	48.61	7.00e-119	422.00
IUUC-Cja-018741	Callithrix jacchus	53.04	9.00e-126	445.00
IUUC-Cfa-020083	Canis familiaris	52.69	3.00e-126	447.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	61.07	6.00e-158	548.00
IUUC-Csa-023853	Chlorocebus sabaeus	52.69	3.00e-126	447.00
IUUC-Cho-024718	Choloepus hoffmanni	54.19	1.00e-116	414.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	38.10	5.00e-139	489.00
IUUC-Dno-029680	Dasypus novemcinctus	52.69	4.00e-126	447.00
IUUC-Dor-030902	Dipodomys ordii	46.84	2.00e-105	378.00
IUUC-Dme-032122	Drosophila melanogaster	50.11	3.00e-122	434.00
IUUC-Eca-033915	Equus caballus	51.88	5.00e-124	439.00
IUUC-Eeu-034963	Erinaceus europaeus	52.34	3.00e-124	440.00
IUUC-Fca-035824	Felis catus	52.69	4.00e-126	447.00
IUUC-Fso-038464	Fusarium solani	44.30	4.00e-139	489.00
IUUC-Ggr-039946	Gaeumannomyces graminis	38.63	2.00e-134	474.00
IUUC-Gga-040309	Gallus gallus	56.37	8.00e-98	348.00
IUUC-Gma-044247	Glycine max	60.96	0.00e+00	2304.00
IUUC-Hsa-046879	Homo sapiens	52.69	3.00e-126	447.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	52.33	2.00e-126	446.00
IUUC-Kpa-049228	Komagataella pastoris	39.53	8.00e-131	462.00
IUUC-Lch-050252	Latimeria chalumnae	52.80	2.00e-125	444.00
IUUC-Lpe-050915	Leersia perrieri	55.93	0.00e+00	3461.00
IUUC-Loc-052472	Lepisosteus oculatus	52.69	4.00e-126	446.00
IUUC-Lma-053159	Leptosphaeria maculans	30.90	3.00e-147	516.00
IUUC-Laf-054154	Loxodonta africana	52.69	3.00e-126	447.00
IUUC-Mcc-055085	Macaca mulatta	52.69	3.00e-126	447.00
IUUC-Meu-056897	Macropus eugenii	46.76	4.00e-76	278.00
IUUC-Mtr-058128	Medicago truncatula	58.48	0.00e+00	2204.00
IUUC-Mvi-060320	Microbotryum violaceum	36.39	2.00e-124	441.00
IUUC-Mmr-060820	Microcebus murinus	52.69	3.00e-126	447.00
IUUC-Mdo-062930	Monodelphis domestica	52.69	2.00e-126	447.00
IUUC-Mmu-063601	Mus musculus	52.69	2.00e-126	447.00
IUUC-Mac-065557	Musa acuminata	54.30	0.00e+00	1593.00
IUUC-Mpu-066653	Mustela putorius furo	52.69	2.00e-126	447.00
IUUC-Mlu-067418	Myotis lucifugus	52.69	3.00e-126	447.00
IUUC-Nfi-068278	Neosartorya fischeri	39.25	7.00e-141	495.00
IUUC-Ncr-068813	Neurospora crassa	39.68	1.00e-144	508.00
IUUC-Nle-069418	Nomascus leucogenys	52.69	3.00e-126	447.00
IUUC-Opr-070443	Ochotona princeps	43.62	3.00e-93	335.00
IUUC-Ont-071300	Oreochromis niloticus	52.69	4.00e-126	447.00
IUUC-Oan-073046	Ornithorhynchus anatinus	52.45	4.00e-125	443.00
IUUC-Ocu-074178	Oryctolagus cuniculus	52.69	2.00e-126	447.00
IUUC-Oba-075252	Oryza barthii	53.83	0.00e+00	2133.00
IUUC-Obr-076762	Oryza brachyantha	55.94	0.00e+00	3439.00
IUUC-Ogl-077590	Oryza glaberrima	58.36	0.00e+00	1244.00
IUUC-Ogu-077981	Oryza glumaepatula	54.10	0.00e+00	2099.00
IUUC-Oin-079663	Oryza indica	51.36	0.00e+00	1884.00
IUUC-Olo-080326	Oryza longistaminata	53.87	0.00e+00	2138.00
IUUC-Ome-081289	Oryza meridionalis	67.97	0.00e+00	1099.00
IUUC-Oni-082342	Oryza nivara	53.89	0.00e+00	2162.00
IUUC-Opu-083428	Oryza punctata	56.32	0.00e+00	3416.00
IUUC-Oru-084559	Oryza rufipogon	53.83	0.00e+00	2129.00
IUUC-Osa-086200	Oryza sativa	65.93	0.00e+00	1277.00
IUUC-Olu-087813	Ostreococcus lucimarinus	51.34	1.00e-125	441.00
IUUC-Oga-088903	Otolemur garnettii	52.69	3.00e-126	447.00
IUUC-Oar-090210	Ovis aries	52.69	5.00e-126	446.00
IUUC-Pan-092368	Papio anubis	51.65	3.00e-112	400.00
IUUC-Pno-094871	Phaeosphaeria nodorum	33.98	9.00e-138	485.00
IUUC-Ppa-095657	Physcomitrella patens	50.74	0.00e+00	1784.00
IUUC-Pab-098583	Pongo abelii	52.69	3.00e-126	447.00
IUUC-Pop-099520	Populus trichocarpa	61.09	0.00e+00	2341.00
IUUC-Pca-100596	Procavia capensis	38.66	7.00e-89	320.00
IUUC-Ppe-102109	Prunus persica	63.46	0.00e+00	4167.00
IUUC-Pva-102116	Pteropus vampyrus	48.36	2.00e-111	397.00
IUUC-Pte-104018	Pyrenophora teres	30.74	8.00e-147	515.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	31.28	6.00e-143	502.00
IUUC-Sce-106449	Saccharomyces cerevisiae	36.73	8.00e-126	445.00
IUUC-Sha-106961	Sarcophilus harrisii	52.69	2.00e-126	447.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	37.77	9.00e-132	465.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	45.80	1.00e-97	350.00
IUUC-Sit-110149	Setaria italica	55.70	0.00e+00	3368.00
IUUC-Sly-111285	Solanum lycopersicum	59.28	0.00e+00	3869.00
IUUC-Stu-112501	Solanum tuberosum	68.27	9.00e-133	465.00
IUUC-Sar-113291	Sorex araneus	52.38	7.00e-122	432.00
IUUC-Sbi-113794	Sorghum bicolor	56.77	0.00e+00	1409.00
IUUC-Ssc-115754	Sus scrofa	52.69	3.00e-126	447.00
IUUC-Tni-120836	Tetraodon nigroviridis	52.22	4.00e-123	436.00
IUUC-Tca-121646	Theobroma cacao	64.01	0.00e+00	2446.00
IUUC-Tre-121909	Trichoderma reesei	40.20	5.00e-143	503.00
IUUC-Tme-127172	Tuber melanosporum	37.26	4.00e-135	476.00
IUUC-Tbe-127793	Tupaia belangeri	37.58	1.00e-85	310.00
IUUC-Ttr-129253	Tursiops truncatus	52.69	5.00e-126	446.00
IUUC-Vda-129886	Verticillium dahliae	47.14	6.00e-137	483.00
IUUC-Vpa-130708	Vicugna pacos	52.69	1.00e-125	445.00
IUUC-Vvi-131559	Vitis vinifera	65.88	0.00e+00	1774.00
IUUC-Xtr-132123	Xenopus tropicalis	49.88	6.00e-113	403.00
IUUC-Zma-135595	Zea mays	53.98	0.00e+00	3370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence