iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000025597.13	ENSMUST00000113371.7	ENSMUSP00000108998.1
ENSMUSG00000025597.13	ENSMUST00000040504.11	ENSMUSP00000038080.5
ENSMUSG00000025597.13	ENSMUST00000133447.1	ENSMUSP00000118072.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.30e-16	60.2	181	247
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.40e-06	26.4	280	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e + +++v+i++v+p +++ l+++ Ytg l++ 
   Q: 181  CDVLLIAGPLKIPAHRLVLSAVSDYFAAMFTNDVLEAR-QEEVKIEGVDPNALNSLVQYAYTGVLQLR 247
           8************************************9.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c +L  +a++++  hF
   Q: 280  PSNCLGIRSFGDAQGCMELQNVAHKYAMEHF 310
           89************************98887 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGSCLQQEG YEHRGTPVQG RLKNHSRDRN 60
GLKKSNSPVH HDILTPVPGP APTHQRVLQN WHQQNVIVHL QANEDTPKAV PEGNLLKEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTCTACAC AAGAGGCAGA GAGAAACAAG AGATAACAAA GGCTCCATTT CCTTTCTGTT 60
AGAGAAGGCT TTTGTCTTTT CTCAGGCAAC AATGTCAGTG TCCGGCAAGA AAGAGTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0015630--C:microtubule cytoskeleton
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	85.12	0.00e+00	1213.00
IUUC-Apl-004156	Anas platyrhynchos	83.66	0.00e+00	968.00
IUUC-Aca-004238	Anolis carolinensis	76.71	0.00e+00	1101.00
IUUC-Ame-011287	Astyanax mexicanus	67.37	0.00e+00	887.00
IUUC-Bta-013232	Bos taurus	83.64	0.00e+00	1087.00
IUUC-Cja-018916	Callithrix jacchus	86.55	0.00e+00	1234.00
IUUC-Cfa-020972	Canis familiaris	86.74	0.00e+00	1013.00
IUUC-Csa-023849	Chlorocebus sabaeus	87.31	0.00e+00	1276.00
IUUC-Dor-030708	Dipodomys ordii	82.23	0.00e+00	1169.00
IUUC-Ete-033156	Echinops telfairi	77.91	0.00e+00	776.00
IUUC-Eca-033542	Equus caballus	86.75	0.00e+00	1242.00
IUUC-Fal-036999	Ficedula albicollis	77.99	0.00e+00	1142.00
IUUC-Gga-040215	Gallus gallus	78.44	0.00e+00	1157.00
IUUC-Ggo-045074	Gorilla gorilla	87.73	0.00e+00	1285.00
IUUC-Hsa-046486	Homo sapiens	87.45	0.00e+00	1255.00
IUUC-Loc-052015	Lepisosteus oculatus	75.10	0.00e+00	1055.00
IUUC-Laf-053627	Loxodonta africana	85.91	0.00e+00	1251.00
IUUC-Mcc-055418	Macaca mulatta	87.45	0.00e+00	1281.00
IUUC-Meu-056859	Macropus eugenii	70.33	1.00e-142	499.00
IUUC-Mga-059582	Meleagris gallopavo	77.97	0.00e+00	1090.00
IUUC-Mmr-061648	Microcebus murinus	88.28	0.00e+00	1298.00
IUUC-Mdo-062785	Monodelphis domestica	82.25	0.00e+00	936.00
IUUC-Mpu-066279	Mustela putorius furo	85.86	0.00e+00	1003.00
IUUC-Mlu-067981	Myotis lucifugus	84.52	0.00e+00	1240.00
IUUC-Ncr-068856	Neurospora crassa	37.74	3.00e-04	39.30
IUUC-Nle-070033	Nomascus leucogenys	87.12	0.00e+00	1248.00
IUUC-Ont-071932	Oreochromis niloticus	71.68	0.00e+00	1039.00
IUUC-Ocu-073854	Oryctolagus cuniculus	87.01	0.00e+00	1026.00
IUUC-Ola-087436	Oryzias latipes	71.17	0.00e+00	1014.00
IUUC-Oar-089952	Ovis aries	85.77	0.00e+00	1254.00
IUUC-Ptr-091649	Pan troglodytes	81.45	0.00e+00	1129.00
IUUC-Pan-091798	Papio anubis	87.59	0.00e+00	1281.00
IUUC-Psi-093728	Pelodiscus sinensis	77.89	0.00e+00	1143.00
IUUC-Pfo-096954	Poecilia formosa	71.70	0.00e+00	1026.00
IUUC-Pab-098461	Pongo abelii	87.17	0.00e+00	1266.00
IUUC-Pva-102458	Pteropus vampyrus	86.27	0.00e+00	1132.00
IUUC-Rno-105865	Rattus norvegicus	96.09	0.00e+00	1411.00
IUUC-Sha-107322	Sarcophilus harrisii	81.88	0.00e+00	954.00
IUUC-Ssc-116001	Sus scrofa	88.38	0.00e+00	1292.00
IUUC-Tgu-116994	Taeniopygia guttata	78.97	0.00e+00	1158.00
IUUC-Tni-120794	Tetraodon nigroviridis	69.03	0.00e+00	964.00
IUUC-Tbe-128118	Tupaia belangeri	71.29	0.00e+00	908.00
IUUC-Ttr-129220	Tursiops truncatus	80.26	0.00e+00	1139.00
IUUC-Vpa-130811	Vicugna pacos	82.74	0.00e+00	1171.00
IUUC-Xtr-132358	Xenopus tropicalis	76.66	0.00e+00	1125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence