iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118466

Ensembl Protein ID

ENSTRUP00000014959.1

UniProt Accession

H2SRC2; H2SRC2_TAKRU

Protein Name

Ubiquitin-like protein ATG12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006154.1	ENSTRUT00000015028.1	ENSTRUP00000014959.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UBL/ATG12	81.40	2.00e-38	154.00	IUUC-Hsa-046903

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Functional Description
(View)

Ubiquitin-like protein involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

VDLLLKAVGD TPIMKQKKWA VERGRTVQSL SQFISRFLKL DAGEQLFIYV NQSFAPSPDQ 60
DVGVLFDCFG SDGKLVLHYC KSQAWG 86

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Nucleotide Sequence
(Fasta)

GTCGATTTGC TGCTGAAGGC TGTGGGCGAT ACCCCGATCA TGAAGCAGAA GAAGTGGGCT 60
GTGGAGCGGG GGCGGACGGT GCAGTCCCTG TCTCAGTTCA TCTCTCGCTT CCTCAAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007242--Atg12
IPR029071--Ubiquitin-rel_dom

Pfam

PF04110--APG12

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0034045--C:pre-autophagosomal structure membrane
GO:0019776--F:Atg8 ligase activity
GO:0000045--P:autophagosome assembly
GO:0006501--P:C-terminal protein lipidation
GO:0000422--P:mitophagy
GO:0044804--P:nucleophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001177	Aegilops tauschii	40.24	9.00e-14	67.80
IUUC-Aml-002116	Ailuropoda melanoleuca	81.40	5.00e-39	153.00
IUUC-Atr-002615	Amborella trichopoda	45.12	3.00e-15	72.80
IUUC-Apl-003753	Anas platyrhynchos	87.50	2.00e-18	82.80
IUUC-Aca-005231	Anolis carolinensis	80.23	6.00e-34	135.00
IUUC-Aly-006172	Arabidopsis lyrata	42.68	1.00e-14	70.90
IUUC-Ath-006953	Arabidopsis thaliana	43.90	5.00e-15	72.00
IUUC-Ago-007970	Ashbya gossypii	43.90	1.00e-05	42.70
IUUC-Acl-008072	Aspergillus clavatus	27.91	1.00e-08	51.60
IUUC-Afl-008725	Aspergillus flavus	29.07	9.00e-09	52.80
IUUC-Afu-008967	Aspergillus fumigatus	27.91	2.00e-08	51.60
IUUC-Ani-009248	Aspergillus nidulans	26.74	3.00e-08	50.80
IUUC-Ang-009684	Aspergillus niger	27.91	2.00e-08	52.00
IUUC-Aor-009947	Aspergillus oryzae	29.07	9.00e-09	52.80
IUUC-Ame-011656	Astyanax mexicanus	90.70	4.00e-44	169.00
IUUC-Bgr-012174	Blumeria graminis	31.03	6.00e-10	56.20
IUUC-Bta-012483	Bos taurus	81.40	4.00e-39	152.00
IUUC-Bci-013755	Botrytis cinerea	29.79	7.00e-08	48.90
IUUC-Bdi-014156	Brachypodium distachyon	37.80	2.00e-13	67.00
IUUC-Bol-015683	Brassica oleracea	42.68	1.00e-14	70.90
IUUC-Bra-016802	Brassica rapa	42.68	9.00e-15	70.90
IUUC-Cel-018242	Caenorhabditis elegans	32.22	5.00e-11	59.30
IUUC-Cja-019514	Callithrix jacchus	81.40	6.00e-39	153.00
IUUC-Cfa-020748	Canis familiaris	81.40	5.00e-39	153.00
IUUC-Cpo-021965	Cavia porcellus	81.40	8.00e-39	152.00
IUUC-Cre-023009	Chlamydomonas reinhardtii	33.72	3.00e-10	55.80
IUUC-Csa-023494	Chlorocebus sabaeus	81.40	4.00e-39	153.00
IUUC-Cho-024631	Choloepus hoffmanni	81.40	7.00e-39	152.00
IUUC-Cin-025609	Ciona intestinalis	56.98	5.00e-28	115.00
IUUC-Cgl-026722	Colletotrichum gloeosporioides	37.35	1.00e-10	58.90
IUUC-Dre-027479	Danio rerio	86.05	2.00e-42	163.00
IUUC-Dno-029693	Dasypus novemcinctus	66.28	4.00e-28	116.00
IUUC-Dse-031440	Dothistroma septosporum	33.72	2.00e-10	58.20
IUUC-Dme-031892	Drosophila melanogaster	55.95	1.00e-27	114.00
IUUC-Ete-032550	Echinops telfairi	82.35	1.00e-38	151.00
IUUC-Eca-033553	Equus caballus	81.40	3.00e-39	153.00
IUUC-Fca-036524	Felis catus	81.40	8.00e-38	149.00
IUUC-Fal-036942	Ficedula albicollis	80.23	6.00e-39	151.00
IUUC-Fox-037753	Fusarium oxysporum	32.93	3.00e-09	53.90
IUUC-Gmo-039498	Gadus morhua	83.72	1.00e-41	160.00
IUUC-Ggr-039852	Gaeumannomyces graminis	31.65	2.00e-08	52.40
IUUC-Gga-041263	Gallus gallus	81.40	1.00e-39	154.00
IUUC-Gac-042346	Gasterosteus aculeatus	92.86	2.00e-43	167.00
IUUC-Gma-042896	Glycine max	45.12	3.00e-15	72.80
IUUC-Ggo-045601	Gorilla gorilla	81.40	7.00e-39	152.00
IUUC-Hsa-046903	Homo sapiens	81.40	3.00e-39	153.00
IUUC-Hvu-047239	Hordeum vulgare	41.46	7.00e-14	68.20
IUUC-Itr-048445	Ictidomys tridecemlineatus	81.40	5.00e-39	153.00
IUUC-Kpa-049355	Komagataella pastoris	27.27	2.00e-06	44.70
IUUC-Lch-050619	Latimeria chalumnae	80.23	2.00e-40	157.00
IUUC-Loc-052102	Lepisosteus oculatus	74.58	1.00e-21	94.40
IUUC-Lma-053299	Leptosphaeria maculans	29.23	7.00e-05	38.90
IUUC-Laf-054205	Loxodonta africana	81.40	1.00e-39	154.00
IUUC-Meu-056804	Macropus eugenii	81.40	3.00e-39	153.00
IUUC-Mor-057052	Magnaporthe oryzae	31.65	1.00e-09	56.20
IUUC-Mtr-057961	Medicago truncatula	43.90	7.00e-15	71.60
IUUC-Mla-059045	Melampsora laricipopulina	39.02	2.00e-16	77.00
IUUC-Mvi-060360	Microbotryum violaceum	40.24	4.00e-17	79.70
IUUC-Mmr-061654	Microcebus murinus	81.40	2.00e-39	153.00
IUUC-Mdo-062649	Monodelphis domestica	81.40	2.00e-39	154.00
IUUC-Mmu-064105	Mus musculus	81.40	4.00e-39	153.00
IUUC-Mac-065532	Musa acuminata	42.68	8.00e-16	74.70
IUUC-Mpu-066269	Mustela putorius furo	81.40	1.00e-39	155.00
IUUC-Mlu-067631	Myotis lucifugus	81.40	4.00e-39	153.00
IUUC-Nfi-068468	Neosartorya fischeri	27.91	4.00e-09	53.10
IUUC-Ncr-068750	Neurospora crassa	28.74	8.00e-08	49.70
IUUC-Nle-069483	Nomascus leucogenys	81.40	5.00e-39	153.00
IUUC-Opr-070936	Ochotona princeps	81.40	1.00e-38	152.00
IUUC-Obr-076322	Oryza brachyantha	34.15	5.00e-12	62.00
IUUC-Ogl-077226	Oryza glaberrima	34.15	5.00e-12	62.00
IUUC-Oin-079220	Oryza indica	46.51	1.00e-08	50.80
IUUC-Olo-080688	Oryza longistaminata	34.15	5.00e-12	62.00
IUUC-Ome-081265	Oryza meridionalis	34.15	5.00e-12	62.00
IUUC-Oru-084342	Oryza rufipogon	33.72	7.00e-11	60.50
IUUC-Osa-086212	Oryza sativa	34.15	5.00e-12	62.00
IUUC-Ola-087277	Oryzias latipes	88.37	2.00e-43	166.00
IUUC-Olu-087780	Ostreococcus lucimarinus	35.56	3.00e-10	56.20
IUUC-Oga-088175	Otolemur garnettii	81.40	2.00e-39	154.00
IUUC-Oar-089477	Ovis aries	81.40	8.00e-39	152.00
IUUC-Ptr-091129	Pan troglodytes	81.40	8.00e-39	152.00
IUUC-Psi-093351	Pelodiscus sinensis	81.40	2.00e-39	154.00
IUUC-Pno-094948	Phaeosphaeria nodorum	27.87	4.00e-04	37.00
IUUC-Ppa-095788	Physcomitrella patens	40.70	1.00e-15	74.30
IUUC-Pfo-096993	Poecilia formosa	89.53	1.00e-43	167.00
IUUC-Pab-098502	Pongo abelii	81.40	7.00e-39	153.00
IUUC-Pop-098819	Populus trichocarpa	41.46	9.00e-14	67.80
IUUC-Pca-100144	Procavia capensis	61.63	8.00e-25	106.00
IUUC-Ppe-101560	Prunus persica	43.90	7.00e-15	71.20
IUUC-Pva-102810	Pteropus vampyrus	76.12	8.00e-27	112.00
IUUC-Pgr-103531	Puccinia graminis	38.37	5.00e-17	79.30
IUUC-Ptt-103753	Puccinia triticina	38.37	5.00e-17	79.30
IUUC-Pyt-104733	Pyrenophora triticirepentis	30.23	8.00e-09	52.40
IUUC-Rno-106072	Rattus norvegicus	81.40	3.00e-39	153.00
IUUC-Sce-106275	Saccharomyces cerevisiae	42.59	1.00e-08	53.10
IUUC-Sha-107554	Sarcophilus harrisii	81.40	2.00e-39	154.00
IUUC-Sja-107682	Schizosaccharomyces japonicus	27.91	6.00e-11	59.30
IUUC-Spo-108275	Schizosaccharomyces pombe	37.21	6.00e-16	75.90
IUUC-Smo-109151	Selaginella moellendorffii	31.25	4.00e-10	55.50
IUUC-Sit-110270	Setaria italica	40.24	3.00e-14	69.30
IUUC-Sly-111862	Solanum lycopersicum	43.90	1.00e-14	70.90
IUUC-Stu-112663	Solanum tuberosum	46.94	2.00e-09	53.90
IUUC-Sbi-114148	Sorghum bicolor	40.24	3.00e-14	69.30
IUUC-Sre-115216	Sporisorium reilianum	38.37	1.00e-17	82.00
IUUC-Ssc-116051	Sus scrofa	81.40	3.00e-39	153.00
IUUC-Tgu-117008	Taeniopygia guttata	71.74	8.00e-15	71.60
IUUC-Tsy-119334	Tarsius syrichta	73.26	7.00e-33	133.00
IUUC-Tni-119792	Tetraodon nigroviridis	97.67	7.00e-46	174.00
IUUC-Tca-121861	Theobroma cacao	43.90	1.00e-14	71.20
IUUC-Tvi-122499	Trichoderma virens	34.15	5.00e-10	56.20
IUUC-Tae-123431	Triticum aestivum	40.24	9.00e-14	67.80
IUUC-Tme-126934	Tuber melanosporum	27.91	1.00e-10	58.90
IUUC-Ttr-129001	Tursiops truncatus	76.74	1.00e-33	135.00
IUUC-Uma-129324	Ustilago maydis	37.21	2.00e-17	80.90
IUUC-Vda-129846	Verticillium dahliae	30.12	4.00e-08	50.40
IUUC-Vpa-130202	Vicugna pacos	90.00	4.00e-19	87.40
IUUC-Vvi-131474	Vitis vinifera	38.46	6.00e-08	49.70
IUUC-Xtr-132782	Xenopus tropicalis	79.07	1.00e-39	154.00
IUUC-Xma-134140	Xiphophorus maculatus	91.86	7.00e-45	172.00
IUUC-Yli-134517	Yarrowia lipolytica	32.50	2.00e-07	48.90
IUUC-Zma-134764	Zea mays	40.24	3.00e-14	69.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence