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Tag Content
UUCD2 ID IUUC-Cja-018926
UUCD1 version UUC-CaJ-00303
Ensembl Protein ID ENSCJAP00000016175.2
UniProt Accession F7A7I1; F7A7I1_CALJA
Genbank Protein ID JAB07787.1; JAB15981.1; JAB36089.1
Protein Name E3 ubiquitin-protein ligase RFWD2 isoform a
Genbank Nucleotide ID ACFV01044858; GAMS01007155; GAMQ01005762
Gene Name RFWD2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000008662.2 ENSCJAT00000017096.2 ENSCJAP00000016175.2
ENSCJAG00000008662.2 ENSCJAT00000017089.2 ENSCJAP00000016168.2
ENSCJAG00000008662.2 ENSCJAT00000017067.2 ENSCJAP00000016150.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.00e-06 28.2 136 174
E3 adaptor/Cullin RING/DCX/DWD 1.20e-23 83.1 470 499
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 136  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 174
           ********99.888***********9555......999999****6 PP
   

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 470  NSKISCISWssYHkNLLASSDYEGTVILWD 499
           689******9622599************** PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MSGSRQAGSG SAGTSPGSSA ASSVTSASSS LSSSPSPPSV AASAAAPVSG GAAQAAGSGG 60
LGGPVRPVLV APAVSGSGGG AVSTGLSRHS CAARPSAGVG GSSSSLGSGS RKRPLLAPLC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-018926|E3,RING;E3,WD_repeat|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGACCGCGG CGGCGGCGGC GGCCTGGACA GCTGTTGTGC CTTCTACTCC CCTTTTTTAG 60
TTTCCTCCGC CCCCTCCCGT CGGACGCCGT GGTGTGGCTG CCTTAAAAAA ACGCAACTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-018926|E3,RING;E3,WD_repeat|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00400--WD40
SMART

SM00184--RING
SM00320--WD40
Gene Ontology

GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation
KEGG cjc:100394332
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000885 Aegilops tauschii 40.25 2.00e-127 449.00
IUUC-Aml-001265 Ailuropoda melanoleuca 99.68 0.00e+00 1246.00
IUUC-Atr-002460 Amborella trichopoda 38.67 8.00e-125 441.00
IUUC-Apl-003796 Anas platyrhynchos 98.11 0.00e+00 1157.00
IUUC-Aca-005078 Anolis carolinensis 97.42 0.00e+00 1210.00
IUUC-Aly-006014 Arabidopsis lyrata 40.09 2.00e-130 459.00
IUUC-Ath-007636 Arabidopsis thaliana 39.57 4.00e-130 458.00
IUUC-Ame-011176 Astyanax mexicanus 75.81 3.00e-71 263.00
IUUC-Bta-012595 Bos taurus 99.22 0.00e+00 1258.00
IUUC-Bdi-014152 Brachypodium distachyon 38.98 1.00e-128 453.00
IUUC-Bol-016380 Brassica oleracea 40.27 3.00e-131 462.00
IUUC-Bra-017690 Brassica rapa 39.30 4.00e-126 445.00
IUUC-Cfa-021088 Canis familiaris 98.91 0.00e+00 1258.00
IUUC-Cpo-022442 Cavia porcellus 98.11 0.00e+00 1223.00
IUUC-Cre-022579 Chlamydomonas reinhardtii 33.45 3.00e-33 135.00
IUUC-Csa-024119 Chlorocebus sabaeus 97.69 0.00e+00 1251.00
IUUC-Cho-024883 Choloepus hoffmanni 66.56 2.00e-106 379.00
IUUC-Cin-025375 Ciona intestinalis 55.64 0.00e+00 680.00
IUUC-Cme-027350 Cyanidioschyzon merolae 41.62 1.00e-79 291.00
IUUC-Dre-028453 Danio rerio 87.72 0.00e+00 1086.00
IUUC-Dno-029887 Dasypus novemcinctus 98.75 0.00e+00 1249.00
IUUC-Dor-031110 Dipodomys ordii 89.94 0.00e+00 876.00
IUUC-Ete-033016 Echinops telfairi 84.34 0.00e+00 1037.00
IUUC-Eca-034403 Equus caballus 98.96 0.00e+00 1155.00
IUUC-Eeu-034690 Erinaceus europaeus 82.02 0.00e+00 958.00
IUUC-Fca-036475 Felis catus 98.62 0.00e+00 1160.00
IUUC-Fal-037189 Ficedula albicollis 98.66 0.00e+00 1194.00
IUUC-Gmo-039245 Gadus morhua 86.79 0.00e+00 1058.00
IUUC-Gga-040806 Gallus gallus 98.39 0.00e+00 1240.00
IUUC-Gac-042177 Gasterosteus aculeatus 88.16 0.00e+00 1104.00
IUUC-Gma-044187 Glycine max 40.64 2.00e-127 449.00
IUUC-Ggo-044430 Gorilla gorilla 98.31 0.00e+00 927.00
IUUC-Hsa-045853 Homo sapiens 99.38 0.00e+00 1259.00
IUUC-Hvu-047750 Hordeum vulgare 38.79 5.00e-95 343.00
IUUC-Itr-048238 Ictidomys tridecemlineatus 99.58 5.00e-144 503.00
IUUC-Lch-050420 Latimeria chalumnae 92.04 0.00e+00 1150.00
IUUC-Lpe-051219 Leersia perrieri 38.50 9.00e-124 437.00
IUUC-Loc-052728 Lepisosteus oculatus 91.45 0.00e+00 1108.00
IUUC-Laf-053775 Loxodonta africana 98.13 0.00e+00 1251.00
IUUC-Meu-056595 Macropus eugenii 77.93 4.00e-178 618.00
IUUC-Mtr-058555 Medicago truncatula 40.39 4.00e-134 472.00
IUUC-Mga-059646 Meleagris gallopavo 97.77 0.00e+00 1156.00
IUUC-Mmr-060990 Microcebus murinus 99.22 0.00e+00 1253.00
IUUC-Mdo-062287 Monodelphis domestica 98.87 0.00e+00 1246.00
IUUC-Mmu-064097 Mus musculus 98.76 0.00e+00 1258.00
IUUC-Mac-065240 Musa acuminata 41.37 4.00e-136 478.00
IUUC-Mpu-066612 Mustela putorius furo 98.63 0.00e+00 1164.00
IUUC-Mlu-067967 Myotis lucifugus 96.82 0.00e+00 1162.00
IUUC-Nle-069543 Nomascus leucogenys 99.53 0.00e+00 1263.00
IUUC-Opr-070366 Ochotona princeps 83.41 0.00e+00 712.00
IUUC-Ont-071522 Oreochromis niloticus 87.84 0.00e+00 1093.00
IUUC-Oan-073409 Ornithorhynchus anatinus 98.45 0.00e+00 1157.00
IUUC-Ocu-073756 Oryctolagus cuniculus 98.88 0.00e+00 1228.00
IUUC-Oba-075149 Oryza barthii 39.20 2.00e-126 447.00
IUUC-Obr-076563 Oryza brachyantha 39.45 6.00e-127 447.00
IUUC-Ogl-077701 Oryza glaberrima 39.23 4.00e-127 448.00
IUUC-Ogu-078383 Oryza glumaepatula 39.23 4.00e-127 448.00
IUUC-Oin-079965 Oryza indica 36.72 4.00e-113 402.00
IUUC-Olo-080639 Oryza longistaminata 38.76 1.00e-124 440.00
IUUC-Ome-081821 Oryza meridionalis 38.70 6.00e-115 408.00
IUUC-Oni-082622 Oryza nivara 39.23 4.00e-127 448.00
IUUC-Opu-083295 Oryza punctata 38.92 7.00e-127 447.00
IUUC-Oru-084661 Oryza rufipogon 39.23 4.00e-127 448.00
IUUC-Osa-085766 Oryza sativa 39.23 4.00e-127 448.00
IUUC-Ola-086727 Oryzias latipes 87.82 0.00e+00 1111.00
IUUC-Olu-087702 Ostreococcus lucimarinus 42.86 5.00e-69 254.00
IUUC-Oga-088215 Otolemur garnettii 97.20 0.00e+00 1231.00
IUUC-Oar-089880 Ovis aries 98.90 0.00e+00 1236.00
IUUC-Ptr-090597 Pan troglodytes 99.38 0.00e+00 1259.00
IUUC-Pan-091987 Papio anubis 99.53 0.00e+00 1263.00
IUUC-Psi-094033 Pelodiscus sinensis 97.97 0.00e+00 1166.00
IUUC-Pma-094587 Petromyzon marinus 70.56 0.00e+00 803.00
IUUC-Ppa-095256 Physcomitrella patens 39.10 5.00e-133 468.00
IUUC-Pfo-097388 Poecilia formosa 86.84 0.00e+00 1073.00
IUUC-Pab-098029 Pongo abelii 99.38 0.00e+00 1260.00
IUUC-Pop-099319 Populus trichocarpa 39.23 6.00e-131 461.00
IUUC-Pca-100846 Procavia capensis 90.80 0.00e+00 1141.00
IUUC-Ppe-101250 Prunus persica 38.60 3.00e-121 429.00
IUUC-Pva-102407 Pteropus vampyrus 98.91 0.00e+00 1247.00
IUUC-Rno-105312 Rattus norvegicus 98.76 0.00e+00 1254.00
IUUC-Sha-106514 Sarcophilus harrisii 98.66 0.00e+00 768.00
IUUC-Smo-109418 Selaginella moellendorffii 40.09 3.00e-130 459.00
IUUC-Sit-110248 Setaria italica 38.58 1.00e-127 450.00
IUUC-Sly-110964 Solanum lycopersicum 40.55 7.00e-132 464.00
IUUC-Stu-112882 Solanum tuberosum 40.80 5.00e-133 468.00
IUUC-Sar-113230 Sorex araneus 72.03 0.00e+00 800.00
IUUC-Sbi-113962 Sorghum bicolor 37.04 2.00e-123 436.00
IUUC-Ssc-115987 Sus scrofa 98.82 4.00e-179 620.00
IUUC-Tgu-116471 Taeniopygia guttata 98.38 0.00e+00 1234.00
IUUC-Tru-118231 Takifugu rubripes 87.84 0.00e+00 1061.00
IUUC-Tsy-119415 Tarsius syrichta 98.66 0.00e+00 1170.00
IUUC-Tni-120893 Tetraodon nigroviridis 84.39 0.00e+00 1071.00
IUUC-Tca-121703 Theobroma cacao 41.27 9.00e-130 457.00
IUUC-Tae-125317 Triticum aestivum 41.29 1.00e-135 476.00
IUUC-Tur-126557 Triticum urartu 40.94 8.00e-131 460.00
IUUC-Tbe-127253 Tupaia belangeri 71.01 0.00e+00 843.00
IUUC-Ttr-129100 Tursiops truncatus 97.31 0.00e+00 1139.00
IUUC-Vpa-130613 Vicugna pacos 92.61 0.00e+00 1095.00
IUUC-Vvi-130880 Vitis vinifera 41.13 1.00e-123 436.00
IUUC-Xtr-132033 Xenopus tropicalis 91.64 0.00e+00 1237.00
IUUC-Xma-133421 Xiphophorus maculatus 86.68 0.00e+00 1070.00
Created Date 25-Jun-2017

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