iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089823

Ensembl Protein ID

ENSOARP00000003811.1

UniProt Accession

W5P063; W5P063_SHEEP

Genbank Protein ID

ENSOARP00000003811

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01022532

Gene Name

RNF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003573.1	ENSOART00000003878.1	ENSOARP00000003811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.00e-07	31.6	69	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+++k+   +  C H f+adC+  ++       s++  CP+Cr
   Q: 69   CPICLDMLKNTMTTKECLHRFCADCIiTAL------RSGNKECPTCR 109
           **********555555*********98888......**********8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MCAFNVVKWF ENVSFLGAMS QAVQTNGTQP LSKTWELSLY ELQRTPQEAI TDGLEIVVSP 60
RSLHSELMCP ICLDMLKNTM TTKECLHRFC ADCIITALRS GNKECPTCRK KLVSKRSLRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTGGGGTG GGGGCGCTTT GTGTGCCGAG CCCGCTCTCC CCCCGGGGTG CTAGAGTCGG 60
GGTTGGCGTG TCGAGGCGCT CCTGGGCGTC GGGGTTCCCT GTAGGCGGCG GGGAGACCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000791--C:euchromatin
GO:0071339--C:MLL1 complex
GO:0016604--C:nuclear body
GO:0035102--C:PRC1 complex
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0009948--P:anterior/posterior axis specification
GO:0001702--P:gastrulation with mouth forming second
GO:0007281--P:germ cell development
GO:0036353--P:histone H2A-K119 monoubiquitination
GO:0000278--P:mitotic cell cycle
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000516	Aegilops tauschii	57.81	7.00e-19	88.20
IUUC-Aml-001250	Ailuropoda melanoleuca	99.70	0.00e+00	695.00
IUUC-Apl-003587	Anas platyrhynchos	98.81	0.00e+00	696.00
IUUC-Aca-004928	Anolis carolinensis	98.21	0.00e+00	694.00
IUUC-Aly-005911	Arabidopsis lyrata	50.00	1.00e-22	101.00
IUUC-Ath-006899	Arabidopsis thaliana	48.28	8.00e-23	101.00
IUUC-Ame-010622	Astyanax mexicanus	89.29	0.00e+00	633.00
IUUC-Bta-013553	Bos taurus	100.00	0.00e+00	704.00
IUUC-Bdi-014202	Brachypodium distachyon	55.42	2.00e-24	107.00
IUUC-Bol-015993	Brassica oleracea	48.94	7.00e-24	105.00
IUUC-Bra-017150	Brassica rapa	48.04	6.00e-24	105.00
IUUC-Cja-019093	Callithrix jacchus	99.70	0.00e+00	702.00
IUUC-Cfa-020681	Canis familiaris	99.70	0.00e+00	699.00
IUUC-Cpo-021402	Cavia porcellus	84.52	9.00e-162	562.00
IUUC-Cre-022709	Chlamydomonas reinhardtii	35.48	4.00e-07	49.70
IUUC-Csa-024231	Chlorocebus sabaeus	99.40	0.00e+00	700.00
IUUC-Cho-024843	Choloepus hoffmanni	84.82	2.00e-163	568.00
IUUC-Csv-026314	Ciona savignyi	47.03	1.00e-82	299.00
IUUC-Dre-027685	Danio rerio	89.29	0.00e+00	633.00
IUUC-Dno-029993	Dasypus novemcinctus	99.11	0.00e+00	699.00
IUUC-Dor-030986	Dipodomys ordii	71.43	1.00e-132	465.00
IUUC-Dme-031721	Drosophila melanogaster	78.91	1.00e-67	250.00
IUUC-Ete-032564	Echinops telfairi	82.74	2.00e-161	561.00
IUUC-Eca-033251	Equus caballus	100.00	0.00e+00	704.00
IUUC-Eeu-034951	Erinaceus europaeus	100.00	0.00e+00	704.00
IUUC-Fca-036240	Felis catus	99.70	0.00e+00	697.00
IUUC-Fal-037376	Ficedula albicollis	97.67	0.00e+00	696.00
IUUC-Gmo-038879	Gadus morhua	85.55	5.00e-166	576.00
IUUC-Gga-041134	Gallus gallus	97.92	0.00e+00	692.00
IUUC-Gac-042589	Gasterosteus aculeatus	85.88	2.00e-167	581.00
IUUC-Ggo-044529	Gorilla gorilla	99.40	0.00e+00	700.00
IUUC-Hsa-046100	Homo sapiens	99.40	0.00e+00	700.00
IUUC-Hvu-047152	Hordeum vulgare	54.22	5.00e-24	105.00
IUUC-Itr-047891	Ictidomys tridecemlineatus	99.70	0.00e+00	702.00
IUUC-Lch-049494	Latimeria chalumnae	90.18	3.00e-178	617.00
IUUC-Lpe-050923	Leersia perrieri	44.35	6.00e-25	108.00
IUUC-Loc-052544	Lepisosteus oculatus	87.36	0.00e+00	630.00
IUUC-Laf-053675	Loxodonta africana	99.03	0.00e+00	636.00
IUUC-Mcc-055685	Macaca mulatta	98.25	0.00e+00	704.00
IUUC-Mtr-058234	Medicago truncatula	50.60	9.00e-24	104.00
IUUC-Mga-059354	Meleagris gallopavo	98.21	0.00e+00	693.00
IUUC-Mmr-060809	Microcebus murinus	99.70	0.00e+00	702.00
IUUC-Mdo-062206	Monodelphis domestica	98.82	0.00e+00	701.00
IUUC-Mmu-063715	Mus musculus	99.70	0.00e+00	702.00
IUUC-Mpu-066460	Mustela putorius furo	100.00	0.00e+00	704.00
IUUC-Mlu-067743	Myotis lucifugus	100.00	0.00e+00	704.00
IUUC-Nle-069512	Nomascus leucogenys	99.40	0.00e+00	700.00
IUUC-Opr-070807	Ochotona princeps	99.45	5.00e-106	377.00
IUUC-Ont-072541	Oreochromis niloticus	86.26	1.00e-169	588.00
IUUC-Oan-073454	Ornithorhynchus anatinus	99.41	0.00e+00	702.00
IUUC-Ocu-073981	Oryctolagus cuniculus	99.40	0.00e+00	701.00
IUUC-Oba-075605	Oryza barthii	53.01	9.00e-24	105.00
IUUC-Obr-076282	Oryza brachyantha	44.35	4.00e-25	109.00
IUUC-Ogl-077288	Oryza glaberrima	43.48	7.00e-25	108.00
IUUC-Ogu-078992	Oryza glumaepatula	53.01	1.00e-23	104.00
IUUC-Oin-079939	Oryza indica	43.48	7.00e-25	108.00
IUUC-Olo-080262	Oryza longistaminata	45.22	3.00e-25	110.00
IUUC-Ome-081418	Oryza meridionalis	44.35	5.00e-25	108.00
IUUC-Oni-083103	Oryza nivara	43.48	9.00e-25	108.00
IUUC-Opu-083314	Oryza punctata	44.35	7.00e-25	108.00
IUUC-Oru-084356	Oryza rufipogon	51.81	2.00e-23	103.00
IUUC-Osa-085727	Oryza sativa	43.48	7.00e-25	108.00
IUUC-Ola-086937	Oryzias latipes	87.24	1.00e-169	588.00
IUUC-Oga-089078	Otolemur garnettii	85.37	4.00e-120	423.00
IUUC-Ptr-090557	Pan troglodytes	99.40	0.00e+00	700.00
IUUC-Pan-091950	Papio anubis	99.40	0.00e+00	700.00
IUUC-Psi-093349	Pelodiscus sinensis	98.51	0.00e+00	695.00
IUUC-Ppa-095164	Physcomitrella patens	58.21	7.00e-22	98.20
IUUC-Pfo-096803	Poecilia formosa	84.77	5.00e-169	587.00
IUUC-Pab-098392	Pongo abelii	98.51	0.00e+00	695.00
IUUC-Pop-100011	Populus trichocarpa	50.52	4.00e-25	108.00
IUUC-Pca-100946	Procavia capensis	99.60	3.00e-151	527.00
IUUC-Ppe-101894	Prunus persica	61.82	2.00e-17	83.20
IUUC-Pva-102498	Pteropus vampyrus	99.25	1.00e-77	283.00
IUUC-Rno-105492	Rattus norvegicus	99.70	0.00e+00	702.00
IUUC-Sha-107645	Sarcophilus harrisii	98.51	0.00e+00	695.00
IUUC-Smo-108741	Selaginella moellendorffii	51.95	3.00e-22	95.90
IUUC-Sit-109707	Setaria italica	44.35	2.00e-25	110.00
IUUC-Sly-111537	Solanum lycopersicum	54.41	4.00e-19	89.40
IUUC-Sar-113064	Sorex araneus	97.62	5.00e-72	264.00
IUUC-Sbi-114798	Sorghum bicolor	43.48	2.00e-24	107.00
IUUC-Ssc-115830	Sus scrofa	99.40	0.00e+00	699.00
IUUC-Tgu-116694	Taeniopygia guttata	98.51	0.00e+00	695.00
IUUC-Tru-117837	Takifugu rubripes	85.67	3.00e-167	580.00
IUUC-Tsy-119174	Tarsius syrichta	98.51	0.00e+00	688.00
IUUC-Tni-120389	Tetraodon nigroviridis	85.71	9.00e-167	579.00
IUUC-Tca-121428	Theobroma cacao	43.48	2.00e-24	107.00
IUUC-Tae-125498	Triticum aestivum	54.22	4.00e-24	105.00
IUUC-Tur-126796	Triticum urartu	54.22	5.00e-24	105.00
IUUC-Tbe-127428	Tupaia belangeri	100.00	1.00e-106	377.00
IUUC-Ttr-128796	Tursiops truncatus	99.70	0.00e+00	702.00
IUUC-Vpa-130691	Vicugna pacos	100.00	0.00e+00	704.00
IUUC-Vvi-131143	Vitis vinifera	42.42	3.00e-25	109.00
IUUC-Xtr-132022	Xenopus tropicalis	94.05	0.00e+00	667.00
IUUC-Xma-133424	Xiphophorus maculatus	82.96	4.00e-171	593.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence