iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013294

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Dynein assembly factor with WDR repeat domains 1

Genbank Nucleotide ID

DAAA02006133

Gene Name

DAW1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021327.4	ENSBTAT00000028431.4	ENSBTAP00000028431.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-55	180.9	132	171
UBD/Beta-Prp	2.70e-86	289.6	43	287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH + v+++af  +  + +++Gs D+t+k+W++ tg++ +
   Q: 132  GHRNVVYAIAFnnPYgDKIATGSFDKTCKLWSVETGKCYH 171
           8**********8755788*******************976 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae...........vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
             v  +++ + l+t+sr++ +k+   + +++l + s+h+              t v ++++g+ ++tgs Drt k+wd  +g+ +htl+
   Q: 43   ALVEEIQKAEPLITASRSDQVKLLIQRLQNKLGQHSNHKFYlfkvlrahilpLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLE 131
           4555578888999********9999998888555555543355555555555************************************* PP
   S: 92   ghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           gh + v++++f+  +gdk+++Gs d+t ++w +etg+c++ t++gh++ + c++++p++ l+++Gs D+t +lWd+++g+ + tlt   
   Q: 132  GHRNVVYAIAFNNpYGDKIATGSFDKTCKLWSVETGKCYH-TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQSGEEVFTLTT-A 218
           ***********998**************************.********************************************99.9 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
              + slsf+s g+++++gsl + +++w+  tg+ v+tl+gh + ++s  f  +  ++++gs+D++ ++Wd
   Q: 219  SAEIISLSFTS-GNRIITGSL-SHITVWEADTGRKVYTLIGHCAEISSAVFNWDCSLILTGSMDKTCKLWD 287
           ***********.79******9.68**********************************************8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MKLKSLLLRY YPPGIMLEYE KSGQLKTKSI DLLDLDPSTD VSALVEEIQK AEPLITASRS 60
DQVKLLIQRL QNKLGQHSNH KFYLFKVLRA HILPLTNVAL NKSGSCFITG SYDRTCKLWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTTTCCATG GCGACCAAGT CGGTTGGCTG GTCGTCCCCT AGCGAGAAAA TGAAGCTCAA 60
GAGCCTCCTG CTCCGGTATT ACCCGCCAGG TACGGGCCGG GCCCCCTCTG CTTTCACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0007368--P:determination of left/right symmetry
GO:0007507--P:heart development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002244	Ailuropoda melanoleuca	92.77	0.00e+00	754.00
IUUC-Apl-003764	Anas platyrhynchos	76.34	0.00e+00	634.00
IUUC-Aca-005354	Anolis carolinensis	79.28	0.00e+00	692.00
IUUC-Afl-008745	Aspergillus flavus	35.45	1.00e-57	217.00
IUUC-Afu-008962	Aspergillus fumigatus	36.99	6.00e-56	211.00
IUUC-Ame-010648	Astyanax mexicanus	67.46	4.00e-168	583.00
IUUC-Cja-018728	Callithrix jacchus	90.36	0.00e+00	782.00
IUUC-Cfa-021122	Canis familiaris	93.01	0.00e+00	799.00
IUUC-Cpo-021472	Cavia porcellus	85.57	0.00e+00	712.00
IUUC-Cre-022946	Chlamydomonas reinhardtii	42.60	4.00e-63	234.00
IUUC-Csa-023349	Chlorocebus sabaeus	91.57	0.00e+00	783.00
IUUC-Cho-024337	Choloepus hoffmanni	73.08	3.00e-160	557.00
IUUC-Cin-025447	Ciona intestinalis	66.99	7.00e-175	606.00
IUUC-Csv-026024	Ciona savignyi	66.75	2.00e-174	604.00
IUUC-Dre-028787	Danio rerio	70.49	2.00e-180	624.00
IUUC-Dno-029788	Dasypus novemcinctus	84.82	0.00e+00	713.00
IUUC-Dor-030679	Dipodomys ordii	87.12	2.00e-85	309.00
IUUC-Dme-031913	Drosophila melanogaster	38.54	2.00e-87	316.00
IUUC-Ete-032844	Echinops telfairi	86.73	4.00e-100	357.00
IUUC-Eca-034088	Equus caballus	92.29	0.00e+00	793.00
IUUC-Eeu-034898	Erinaceus europaeus	77.78	4.00e-144	504.00
IUUC-Fca-036058	Felis catus	82.31	0.00e+00	650.00
IUUC-Fal-036638	Ficedula albicollis	75.37	7.00e-150	523.00
IUUC-Gmo-039010	Gadus morhua	67.47	7.00e-146	509.00
IUUC-Ggr-039928	Gaeumannomyces graminis	36.60	3.00e-56	214.00
IUUC-Gga-040984	Gallus gallus	77.05	0.00e+00	667.00
IUUC-Gac-042552	Gasterosteus aculeatus	70.77	1.00e-180	625.00
IUUC-Ggo-044596	Gorilla gorilla	80.00	0.00e+00	646.00
IUUC-Hsa-046535	Homo sapiens	91.81	0.00e+00	786.00
IUUC-Itr-048672	Ictidomys tridecemlineatus	88.81	1.00e-140	491.00
IUUC-Lch-049902	Latimeria chalumnae	81.69	0.00e+00	711.00
IUUC-Loc-051919	Lepisosteus oculatus	80.96	0.00e+00	713.00
IUUC-Laf-053877	Loxodonta africana	89.64	0.00e+00	773.00
IUUC-Mcc-055010	Macaca mulatta	91.57	0.00e+00	783.00
IUUC-Meu-055980	Macropus eugenii	70.26	6.00e-154	536.00
IUUC-Mla-058997	Melampsora laricipopulina	29.97	2.00e-36	147.00
IUUC-Mga-059883	Meleagris gallopavo	70.75	1.00e-171	595.00
IUUC-Mmr-061645	Microcebus murinus	90.91	0.00e+00	774.00
IUUC-Mdo-062166	Monodelphis domestica	88.31	0.00e+00	739.00
IUUC-Mmu-063653	Mus musculus	87.95	0.00e+00	761.00
IUUC-Mpu-066807	Mustela putorius furo	92.38	0.00e+00	782.00
IUUC-Mlu-067792	Myotis lucifugus	89.16	0.00e+00	760.00
IUUC-Nle-069067	Nomascus leucogenys	90.36	0.00e+00	770.00
IUUC-Opr-070841	Ochotona princeps	74.26	2.00e-168	585.00
IUUC-Ont-072191	Oreochromis niloticus	72.95	0.00e+00	644.00
IUUC-Oan-073649	Ornithorhynchus anatinus	82.49	2.00e-100	358.00
IUUC-Ocu-074966	Oryctolagus cuniculus	76.61	5.00e-178	617.00
IUUC-Ola-087021	Oryzias latipes	59.90	1.00e-149	523.00
IUUC-Oga-088193	Otolemur garnettii	90.89	0.00e+00	780.00
IUUC-Oar-089207	Ovis aries	97.35	0.00e+00	828.00
IUUC-Ptr-091298	Pan troglodytes	91.81	0.00e+00	786.00
IUUC-Pan-092620	Papio anubis	90.67	0.00e+00	635.00
IUUC-Psi-093232	Pelodiscus sinensis	81.45	0.00e+00	702.00
IUUC-Ppa-095852	Physcomitrella patens	31.50	6.00e-48	185.00
IUUC-Pfo-096971	Poecilia formosa	71.26	0.00e+00	629.00
IUUC-Pab-098360	Pongo abelii	91.79	0.00e+00	785.00
IUUC-Pca-100384	Procavia capensis	84.82	0.00e+00	739.00
IUUC-Pva-102206	Pteropus vampyrus	90.59	0.00e+00	763.00
IUUC-Pyt-104470	Pyrenophora triticirepentis	35.47	1.00e-58	221.00
IUUC-Rno-105944	Rattus norvegicus	87.95	0.00e+00	763.00
IUUC-Sha-106970	Sarcophilus harrisii	88.31	0.00e+00	740.00
IUUC-Ssl-108470	Sclerotinia sclerotiorum	40.91	1.00e-71	265.00
IUUC-Smo-109147	Selaginella moellendorffii	33.13	1.00e-47	183.00
IUUC-Ssc-115618	Sus scrofa	90.14	0.00e+00	761.00
IUUC-Tgu-117237	Taeniopygia guttata	76.23	0.00e+00	639.00
IUUC-Tsy-119604	Tarsius syrichta	93.15	1.00e-77	283.00
IUUC-Tbe-127358	Tupaia belangeri	73.98	4.00e-176	610.00
IUUC-Ttr-129197	Tursiops truncatus	91.81	0.00e+00	785.00
IUUC-Vpa-130692	Vicugna pacos	86.51	0.00e+00	719.00
IUUC-Xtr-132612	Xenopus tropicalis	78.18	0.00e+00	689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence