iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053398

UUCD1 version

UUC-LoA-00407

Ensembl Protein ID

ENSLAFP00000009996.4

UniProt Accession

G3T8H9; G3T8H9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF180

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000011968.4	ENSLAFT00000011962.4	ENSLAFP00000009996.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	84.08	0.00e+00	999.00	IUUC-Hsa-045752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MKKIEELITK NHNQEEKTIL RCWKCRKCIA SSDCFMKYLE NQVSKDRHDP AGAQNICHVW 60
HMNIEALPEW INCLIQKTQW TVGKLNCPFC GARLGGFNFV STPKCACGQL AAVHLSKSRT 120

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Nucleotide Sequence
(Fasta)

ATGAAAAAAA TTGAAGAATT GATAACTAAA AATCATAATC AAGAAGAAAA AACTATACTT 60
CGTTGTTGGA AATGTAGAAA ATGTATAGCA AGTTCTGATT GTTTCATGAA ATACCTTGAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR033263--RNF180
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031227--C:intrinsic component of endoplasmic reticulum membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030534--P:adult behavior
GO:0042415--P:norepinephrine metabolic process
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0050790--P:regulation of catalytic activity
GO:0042428--P:serotonin metabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002250	Ailuropoda melanoleuca	83.85	0.00e+00	999.00
IUUC-Apl-003598	Anas platyrhynchos	50.52	9.00e-143	500.00
IUUC-Aca-004364	Anolis carolinensis	46.63	2.00e-131	462.00
IUUC-Ame-011498	Astyanax mexicanus	62.98	6.00e-71	259.00
IUUC-Bta-012990	Bos taurus	82.21	0.00e+00	991.00
IUUC-Cja-019420	Callithrix jacchus	84.95	0.00e+00	976.00
IUUC-Cfa-020028	Canis familiaris	84.20	0.00e+00	1002.00
IUUC-Cpo-021698	Cavia porcellus	76.45	0.00e+00	762.00
IUUC-Csa-023637	Chlorocebus sabaeus	83.85	0.00e+00	969.00
IUUC-Cho-025073	Choloepus hoffmanni	72.35	0.00e+00	833.00
IUUC-Dre-027523	Danio rerio	73.03	2.00e-70	259.00
IUUC-Dno-030040	Dasypus novemcinctus	79.00	0.00e+00	737.00
IUUC-Dor-030405	Dipodomys ordii	79.97	0.00e+00	908.00
IUUC-Eca-033366	Equus caballus	84.95	0.00e+00	1018.00
IUUC-Fca-035526	Felis catus	84.98	0.00e+00	778.00
IUUC-Fal-037590	Ficedula albicollis	48.78	5.00e-144	504.00
IUUC-Gmo-039484	Gadus morhua	48.11	9.00e-46	177.00
IUUC-Gga-040136	Gallus gallus	49.13	5.00e-153	534.00
IUUC-Gac-041811	Gasterosteus aculeatus	51.76	5.00e-44	171.00
IUUC-Ggo-044673	Gorilla gorilla	84.26	0.00e+00	976.00
IUUC-Hsa-045752	Homo sapiens	84.08	0.00e+00	972.00
IUUC-Itr-047971	Ictidomys tridecemlineatus	85.47	0.00e+00	1035.00
IUUC-Lch-050309	Latimeria chalumnae	49.48	7.00e-133	467.00
IUUC-Loc-052203	Lepisosteus oculatus	44.25	2.00e-119	422.00
IUUC-Mcc-054745	Macaca mulatta	85.12	0.00e+00	980.00
IUUC-Mmr-060583	Microcebus murinus	84.95	0.00e+00	1017.00
IUUC-Mdo-062873	Monodelphis domestica	68.74	0.00e+00	757.00
IUUC-Mmu-063393	Mus musculus	74.26	0.00e+00	707.00
IUUC-Mac-065655	Musa acuminata	35.71	1.00e-07	50.10
IUUC-Mpu-066186	Mustela putorius furo	82.50	0.00e+00	977.00
IUUC-Mlu-068079	Myotis lucifugus	80.69	0.00e+00	952.00
IUUC-Nle-069164	Nomascus leucogenys	84.78	0.00e+00	978.00
IUUC-Opr-070362	Ochotona princeps	73.17	0.00e+00	833.00
IUUC-Oan-073509	Ornithorhynchus anatinus	47.98	1.00e-52	199.00
IUUC-Ocu-073894	Oryctolagus cuniculus	73.70	0.00e+00	677.00
IUUC-Oga-088485	Otolemur garnettii	83.39	0.00e+00	946.00
IUUC-Oar-089831	Ovis aries	82.47	0.00e+00	988.00
IUUC-Ptr-091570	Pan troglodytes	84.60	0.00e+00	979.00
IUUC-Psi-093962	Pelodiscus sinensis	57.31	0.00e+00	631.00
IUUC-Pfo-096369	Poecilia formosa	69.62	1.00e-64	239.00
IUUC-Pab-098224	Pongo abelii	69.38	0.00e+00	729.00
IUUC-Pca-100186	Procavia capensis	81.66	0.00e+00	894.00
IUUC-Pva-102511	Pteropus vampyrus	84.60	0.00e+00	1009.00
IUUC-Rno-105170	Rattus norvegicus	76.07	0.00e+00	835.00
IUUC-Sha-107501	Sarcophilus harrisii	68.73	0.00e+00	686.00
IUUC-Sja-107944	Schizosaccharomyces japonicus	46.67	2.00e-07	49.30
IUUC-Ssc-115668	Sus scrofa	84.34	0.00e+00	911.00
IUUC-Tgu-117098	Taeniopygia guttata	51.42	1.00e-145	509.00
IUUC-Tru-118625	Takifugu rubripes	72.11	7.00e-64	236.00
IUUC-Tsy-118959	Tarsius syrichta	80.80	0.00e+00	957.00
IUUC-Tni-120324	Tetraodon nigroviridis	33.96	6.00e-66	244.00
IUUC-Tbe-127448	Tupaia belangeri	79.80	0.00e+00	823.00
IUUC-Ttr-128470	Tursiops truncatus	80.62	0.00e+00	922.00
IUUC-Vpa-130097	Vicugna pacos	82.93	0.00e+00	910.00
IUUC-Xtr-132848	Xenopus tropicalis	41.18	1.00e-107	384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence