iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120100

Ensembl Protein ID

ENSTNIP00000000290.1

UniProt Accession

H3BWC8; H3BWC8_TETNG

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000000093.1	ENSTNIT00000003508.1	ENSTNIP00000000290.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-08	35.4	212	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 212  TYC-LCEQVSYGE--MIGCDNdqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 258
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MLGHQYPNAD KSQQLVSYVE DYLECVESLP LDIQRNVSML REIDAKYQDV LKEVDEVFEK 60
YQGEQDGTQK KRLQTQLQRA LIISQELGDE KIHVVTQMTE LIENCSRQMD SHSLCLQEPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGGTC ATCAGTATCC AAATGCAGAC AAGTCACAAC AACTGGTCAG CTATGTGGAG 60
GATTATCTGG AATGTGTGGA GTCTCTGCCT TTGGACATAC AAAGAAATGT TTCTATGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	62.64	8.00e-72	263.00
IUUC-Aca-004990	Anolis carolinensis	60.67	1.00e-74	273.00
IUUC-Bta-012721	Bos taurus	62.64	4.00e-72	264.00
IUUC-Cja-018960	Callithrix jacchus	62.87	2.00e-64	238.00
IUUC-Cfa-020869	Canis familiaris	62.64	2.00e-71	262.00
IUUC-Cpo-021414	Cavia porcellus	62.64	4.00e-72	264.00
IUUC-Csa-023304	Chlorocebus sabaeus	61.90	8.00e-65	239.00
IUUC-Dor-030141	Dipodomys ordii	61.76	6.00e-72	263.00
IUUC-Ete-032709	Echinops telfairi	60.81	7.00e-79	286.00
IUUC-Eca-033432	Equus caballus	62.27	2.00e-71	262.00
IUUC-Eeu-035285	Erinaceus europaeus	62.62	2.00e-56	211.00
IUUC-Fca-036467	Felis catus	62.87	5.00e-72	263.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.50
IUUC-Ggo-045481	Gorilla gorilla	49.59	1.00e-54	206.00
IUUC-Hsa-045837	Homo sapiens	61.90	8.00e-65	239.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	63.24	2.00e-72	265.00
IUUC-Lch-049965	Latimeria chalumnae	61.21	3.00e-82	297.00
IUUC-Mcc-055031	Macaca mulatta	49.79	2.00e-54	206.00
IUUC-Meu-056470	Macropus eugenii	64.26	2.00e-78	285.00
IUUC-Mmr-061385	Microcebus murinus	62.64	1.00e-64	239.00
IUUC-Mdo-062144	Monodelphis domestica	64.26	2.00e-78	285.00
IUUC-Mmu-063215	Mus musculus	62.64	1.00e-72	266.00
IUUC-Mpu-065749	Mustela putorius furo	62.50	2.00e-62	231.00
IUUC-Ocu-074870	Oryctolagus cuniculus	62.87	4.00e-72	264.00
IUUC-Olu-087851	Ostreococcus lucimarinus	67.31	7.00e-19	87.00
IUUC-Oga-088336	Otolemur garnettii	62.64	1.00e-64	239.00
IUUC-Oar-090136	Ovis aries	62.27	1.00e-71	263.00
IUUC-Pan-092819	Papio anubis	61.90	8.00e-65	239.00
IUUC-Pab-098346	Pongo abelii	62.13	1.00e-64	239.00
IUUC-Pca-100278	Procavia capensis	63.50	9.00e-78	282.00
IUUC-Pva-103190	Pteropus vampyrus	62.87	3.00e-72	264.00
IUUC-Rno-104940	Rattus norvegicus	62.27	6.00e-72	263.00
IUUC-Sha-107533	Sarcophilus harrisii	63.88	4.00e-78	284.00
IUUC-Sar-113630	Sorex araneus	62.91	4.00e-56	210.00
IUUC-Ssc-115734	Sus scrofa	62.87	4.00e-72	264.00
IUUC-Tsy-119494	Tarsius syrichta	61.81	2.00e-50	191.00
IUUC-Ttr-128442	Tursiops truncatus	62.62	3.00e-56	211.00
IUUC-Vpa-130063	Vicugna pacos	62.27	3.00e-72	264.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence