iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000004063.7	ENSRNOT00000073675.3	ENSRNOP00000067367.1
ENSRNOG00000004063.7	ENSRNOT00000005478.5	ENSRNOP00000005478.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.40e-24	83.5	120	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +ek  v+y+y+a ++de++l++G vv+vi  +++ egW+k     +gk+G  P+ + +k
   Q: 120  EEKYTVIYPYTARDQDEMNLERGVVVEVI--QKNLEGWWKI--RFQGKEGWAPASYLKK 174
           67889************************..8899****88..9**********99886 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

ALIQLPPYIS QCDEVLQFFE TRPEDLNPPK EEHIGKKKSG SDPTSVDPMV LEQYVVVANY 60
QKQESSEISL SVGQVVDIIE KNESGWWFVS TAEEQGWVPA TCLEGQDGVQ DEFSLQPEEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGCCGC GGCGCAGTAT CGTGGAGGTG AAGGTGCTGG ACGTGCAGAA GAGGCGGGTG 60
CCCAACAAGC ATTATGTGAG TCGGCGTCCG CGCCACGCGG CGACCCCAGC CCCGCGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR030512--SH3PXD2B

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF07653--SH3_2

SMART

SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0002102--C:podosome
GO:0080025--F:phosphatidylinositol-3,5-bisphosphate binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0070273--F:phosphatidylinositol-4-phosphate binding
GO:0010314--F:phosphatidylinositol-5-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity
GO:0060612--P:adipose tissue development
GO:0060348--P:bone development
GO:1904888--P:cranial skeletal system development
GO:0022617--P:extracellular matrix disassembly
GO:0001654--P:eye development
GO:0007507--P:heart development
GO:0002051--P:osteoblast fate commitment
GO:0055114--P:oxidation-reduction process
GO:0071800--P:podosome assembly
GO:1904179--P:positive regulation of adipose tissue development
GO:0045600--P:positive regulation of fat cell differentiation
GO:0010628--P:positive regulation of gene expression
GO:0040018--P:positive regulation of multicellular organism growth
GO:0051496--P:positive regulation of stress fiber assembly
GO:0072657--P:protein localization to membrane
GO:0060378--P:regulation of brood size
GO:0048705--P:skeletal system morphogenesis
GO:0006801--P:superoxide metabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001572	Ailuropoda melanoleuca	85.31	0.00e+00	1300.00
IUUC-Apl-003349	Anas platyrhynchos	63.51	0.00e+00	851.00
IUUC-Aca-004769	Anolis carolinensis	61.92	0.00e+00	869.00
IUUC-Ame-011734	Astyanax mexicanus	47.55	2.00e-103	370.00
IUUC-Bta-012847	Bos taurus	83.46	0.00e+00	1269.00
IUUC-Cja-019338	Callithrix jacchus	84.05	0.00e+00	1237.00
IUUC-Cfa-020751	Canis familiaris	83.93	0.00e+00	1253.00
IUUC-Cpo-021623	Cavia porcellus	84.55	0.00e+00	1254.00
IUUC-Csa-023399	Chlorocebus sabaeus	86.40	0.00e+00	1255.00
IUUC-Cho-024720	Choloepus hoffmanni	83.19	1.00e-101	363.00
IUUC-Dno-029443	Dasypus novemcinctus	82.01	0.00e+00	1149.00
IUUC-Dor-030546	Dipodomys ordii	83.29	0.00e+00	1276.00
IUUC-Ete-032485	Echinops telfairi	70.81	0.00e+00	976.00
IUUC-Eca-033780	Equus caballus	84.20	0.00e+00	1269.00
IUUC-Fca-036365	Felis catus	85.19	0.00e+00	1247.00
IUUC-Fal-036632	Ficedula albicollis	69.95	0.00e+00	689.00
IUUC-Gga-041167	Gallus gallus	61.60	0.00e+00	837.00
IUUC-Gac-041676	Gasterosteus aculeatus	53.48	7.00e-140	491.00
IUUC-Ggo-045275	Gorilla gorilla	85.45	0.00e+00	1249.00
IUUC-Hsa-046483	Homo sapiens	85.45	0.00e+00	1248.00
IUUC-Itr-048237	Ictidomys tridecemlineatus	82.67	0.00e+00	1157.00
IUUC-Lch-049474	Latimeria chalumnae	58.75	0.00e+00	829.00
IUUC-Loc-052659	Lepisosteus oculatus	56.00	4.00e-177	615.00
IUUC-Laf-054220	Loxodonta africana	85.04	0.00e+00	1267.00
IUUC-Mcc-055001	Macaca mulatta	84.52	0.00e+00	1222.00
IUUC-Meu-056086	Macropus eugenii	71.18	0.00e+00	989.00
IUUC-Mga-059772	Meleagris gallopavo	62.64	0.00e+00	854.00
IUUC-Mmr-061321	Microcebus murinus	76.91	0.00e+00	1135.00
IUUC-Mdo-061943	Monodelphis domestica	69.91	0.00e+00	1051.00
IUUC-Mmu-063247	Mus musculus	95.65	0.00e+00	1476.00
IUUC-Mpu-065848	Mustela putorius furo	82.46	0.00e+00	1299.00
IUUC-Mlu-067413	Myotis lucifugus	81.33	0.00e+00	1145.00
IUUC-Nle-069834	Nomascus leucogenys	88.91	0.00e+00	896.00
IUUC-Opr-070355	Ochotona princeps	76.61	0.00e+00	1033.00
IUUC-Ont-072669	Oreochromis niloticus	57.49	1.00e-149	523.00
IUUC-Oan-073473	Ornithorhynchus anatinus	71.48	0.00e+00	728.00
IUUC-Ocu-073822	Oryctolagus cuniculus	79.67	0.00e+00	1226.00
IUUC-Oga-088006	Otolemur garnettii	85.50	0.00e+00	1271.00
IUUC-Oar-090176	Ovis aries	81.81	0.00e+00	1238.00
IUUC-Ptr-090730	Pan troglodytes	83.13	0.00e+00	1199.00
IUUC-Pan-092549	Papio anubis	85.41	0.00e+00	1149.00
IUUC-Pfo-096582	Poecilia formosa	53.33	2.00e-142	500.00
IUUC-Pab-097634	Pongo abelii	85.45	0.00e+00	1250.00
IUUC-Pca-101110	Procavia capensis	78.30	0.00e+00	958.00
IUUC-Pva-103256	Pteropus vampyrus	80.84	0.00e+00	842.00
IUUC-Ssc-115251	Sus scrofa	82.39	0.00e+00	1156.00
IUUC-Tgu-116480	Taeniopygia guttata	61.73	0.00e+00	840.00
IUUC-Tni-120253	Tetraodon nigroviridis	52.98	6.00e-133	468.00
IUUC-Tbe-127871	Tupaia belangeri	82.48	0.00e+00	938.00
IUUC-Ttr-128955	Tursiops truncatus	84.32	0.00e+00	1269.00
IUUC-Xtr-132258	Xenopus tropicalis	56.30	0.00e+00	743.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence