iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090135

Ensembl Protein ID

ENSOARP00000008712.1

UniProt Accession

W5PE48; W5PE48_SHEEP

Genbank Protein ID

ENSOARP00000008712

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01069077

Gene Name

FBXL19

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008120.1	ENSOART00000008839.1	ENSOARP00000008712.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-12	47.9	86	150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede......k....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrs 53
           +vCl+Cge+g+++      +    sl+eC++C+e++Hp+Clk+      ++ e pn+  w+Cp+C++
   Q: 86   AVCLLCGEAGKEDtvegeeEkfglSLMECTICNEIVHPGCLKMGkaegvINAEIPNC--WECPRCTQ 150
           79**********977766516889*******************99************..******97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

VGPPELATLH PQPSALLTPP MSSSSRGPGA GARRRRTRCR RCRACVRTEC GDCHFCRDMK 60
KFGGPGRMKQ SCLLRQCTAP VLPHTAVCLL CGEAGKEDTV EGEEEKFGLS LMECTICNEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGCCCCC CTGAGCTTGC CACCCTCCAC CCACAGCCCT CGGCGTTGCT GACGCCCCCA 60
ATGTCGTCGA GCAGCCGGGG GCCGGGGGCC GGAGCGCGCC GACGCCGAAC CCGCTGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001680	Ailuropoda melanoleuca	85.89	0.00e+00	795.00
IUUC-Aca-004456	Anolis carolinensis	54.87	0.00e+00	640.00
IUUC-Ame-010726	Astyanax mexicanus	58.65	2.00e-86	313.00
IUUC-Bta-012874	Bos taurus	87.46	0.00e+00	873.00
IUUC-Cja-019918	Callithrix jacchus	86.69	0.00e+00	866.00
IUUC-Cfa-020078	Canis familiaris	87.15	0.00e+00	838.00
IUUC-Cpo-021482	Cavia porcellus	86.84	0.00e+00	842.00
IUUC-Csa-023072	Chlorocebus sabaeus	87.31	0.00e+00	871.00
IUUC-Dno-029532	Dasypus novemcinctus	82.35	0.00e+00	778.00
IUUC-Dor-030932	Dipodomys ordii	86.38	0.00e+00	834.00
IUUC-Eca-033707	Equus caballus	87.00	0.00e+00	848.00
IUUC-Eeu-034841	Erinaceus europaeus	78.99	8.00e-125	440.00
IUUC-Fca-036214	Felis catus	86.38	0.00e+00	833.00
IUUC-Gmo-039631	Gadus morhua	60.92	2.00e-80	293.00
IUUC-Ggo-045362	Gorilla gorilla	87.22	0.00e+00	793.00
IUUC-Hsa-046325	Homo sapiens	87.31	0.00e+00	839.00
IUUC-Itr-048488	Ictidomys tridecemlineatus	87.15	0.00e+00	839.00
IUUC-Laf-053994	Loxodonta africana	84.85	0.00e+00	652.00
IUUC-Mcc-054810	Macaca mulatta	87.31	0.00e+00	839.00
IUUC-Meu-056447	Macropus eugenii	93.93	3.00e-120	426.00
IUUC-Mmr-060961	Microcebus murinus	87.15	0.00e+00	869.00
IUUC-Mmu-063602	Mus musculus	84.83	0.00e+00	890.00
IUUC-Mpu-066470	Mustela putorius furo	86.84	0.00e+00	833.00
IUUC-Mlu-068033	Myotis lucifugus	83.83	0.00e+00	723.00
IUUC-Nle-069352	Nomascus leucogenys	87.29	0.00e+00	839.00
IUUC-Opr-070370	Ochotona princeps	86.20	0.00e+00	784.00
IUUC-Ont-071246	Oreochromis niloticus	61.83	6.00e-85	308.00
IUUC-Ocu-074480	Oryctolagus cuniculus	86.07	0.00e+00	820.00
IUUC-Oga-088335	Otolemur garnettii	87.00	0.00e+00	837.00
IUUC-Ptr-091271	Pan troglodytes	80.09	7.00e-141	493.00
IUUC-Pan-092365	Papio anubis	86.84	0.00e+00	868.00
IUUC-Pab-097786	Pongo abelii	80.34	0.00e+00	725.00
IUUC-Pca-100857	Procavia capensis	80.49	3.00e-132	465.00
IUUC-Pva-102613	Pteropus vampyrus	86.84	0.00e+00	850.00
IUUC-Rno-106113	Rattus norvegicus	85.29	0.00e+00	869.00
IUUC-Sha-106914	Sarcophilus harrisii	93.93	2.00e-120	426.00
IUUC-Ssc-115503	Sus scrofa	84.59	0.00e+00	818.00
IUUC-Tru-118079	Takifugu rubripes	63.49	9.00e-83	301.00
IUUC-Tni-120597	Tetraodon nigroviridis	63.07	1.00e-79	291.00
IUUC-Tur-126327	Triticum urartu	40.35	2.00e-03	37.40
IUUC-Tbe-127536	Tupaia belangeri	78.30	0.00e+00	723.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence