iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059648

UUCD1 version

UUC-MeG-00160

Ensembl Protein ID

ENSMGAP00000002946.1

UniProt Accession

G1MW52; G1MW52_MELGA

Protein Name

Uncharacterized protein

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003231.1	ENSMGAT00000003636.1	ENSMGAP00000002946.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	51.82	0.00e+00	954.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.55	2.00e-42	168.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VKRFKKMHLT ADDCEALSKS SEGLSSLTQP LNQRQSRGDV NRGLQPTHRT RRQPRAQGQQ 60
KNIMDYFKIS QKQQVVAGRT KNISIKEELL DPFFAEDDES NISNVMETSS DSSSFLEDEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAGCGAT TTAAGAAAAT GCACCTTACA GCTGACGACT GTGAAGCTCT CAGTAAGAGC 60
TCTGAAGGTT TATCCTCCCT GACACAGCCA CTGAATCAAA GGCAAAGCAG AGGAGATGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF00646--F-box
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000960	Aegilops tauschii	47.73	5.00e-04	39.30
IUUC-Aml-001396	Ailuropoda melanoleuca	51.07	0.00e+00	928.00
IUUC-Atr-002826	Amborella trichopoda	39.39	4.00e-03	37.40
IUUC-Apl-003317	Anas platyrhynchos	75.61	0.00e+00	1424.00
IUUC-Aca-004498	Anolis carolinensis	56.36	0.00e+00	942.00
IUUC-Ath-007293	Arabidopsis thaliana	39.06	3.00e-04	41.20
IUUC-Ani-009226	Aspergillus nidulans	25.16	1.00e-03	38.50
IUUC-Ate-010526	Aspergillus terreus	35.53	3.00e-03	37.40
IUUC-Ame-011808	Astyanax mexicanus	56.21	3.00e-111	394.00
IUUC-Bta-013250	Bos taurus	50.98	0.00e+00	911.00
IUUC-Bol-015348	Brassica oleracea	40.00	2.00e-04	41.60
IUUC-Cja-019638	Callithrix jacchus	51.71	0.00e+00	951.00
IUUC-Cfa-020195	Canis familiaris	58.12	0.00e+00	914.00
IUUC-Cpo-022269	Cavia porcellus	49.53	0.00e+00	871.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	37.80	5.00e-10	60.10
IUUC-Csa-024060	Chlorocebus sabaeus	58.51	0.00e+00	887.00
IUUC-Cho-025003	Choloepus hoffmanni	57.64	5.00e-133	468.00
IUUC-Cin-025694	Ciona intestinalis	28.83	4.00e-30	125.00
IUUC-Dre-028083	Danio rerio	43.11	0.00e+00	761.00
IUUC-Dno-029203	Dasypus novemcinctus	48.82	0.00e+00	848.00
IUUC-Dor-030477	Dipodomys ordii	63.01	1.00e-129	457.00
IUUC-Ete-032861	Echinops telfairi	51.50	0.00e+00	915.00
IUUC-Eca-033205	Equus caballus	51.64	0.00e+00	961.00
IUUC-Eeu-034784	Erinaceus europaeus	60.56	0.00e+00	741.00
IUUC-Fca-035797	Felis catus	50.82	0.00e+00	922.00
IUUC-Gmo-038855	Gadus morhua	44.11	2.00e-120	426.00
IUUC-Gga-040326	Gallus gallus	93.76	0.00e+00	1804.00
IUUC-Gac-042240	Gasterosteus aculeatus	44.83	0.00e+00	638.00
IUUC-Ggo-045050	Gorilla gorilla	49.49	0.00e+00	864.00
IUUC-Hsa-046650	Homo sapiens	51.71	0.00e+00	930.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	61.67	3.00e-105	374.00
IUUC-Lch-050231	Latimeria chalumnae	41.81	1.00e-157	550.00
IUUC-Loc-051884	Lepisosteus oculatus	46.44	0.00e+00	828.00
IUUC-Lma-053267	Leptosphaeria maculans	24.14	2.00e-03	37.70
IUUC-Laf-053843	Loxodonta africana	50.82	0.00e+00	945.00
IUUC-Mcc-055570	Macaca mulatta	51.61	0.00e+00	944.00
IUUC-Meu-056798	Macropus eugenii	48.03	1.00e-104	374.00
IUUC-Mtr-057915	Medicago truncatula	39.06	2.00e-03	38.10
IUUC-Mmr-060757	Microcebus murinus	50.83	0.00e+00	895.00
IUUC-Mdo-061913	Monodelphis domestica	55.50	0.00e+00	874.00
IUUC-Mmu-064337	Mus musculus	50.98	0.00e+00	939.00
IUUC-Mac-064479	Musa acuminata	39.73	7.00e-04	39.30
IUUC-Mpu-066483	Mustela putorius furo	50.97	0.00e+00	939.00
IUUC-Mlu-068204	Myotis lucifugus	49.13	0.00e+00	879.00
IUUC-Ncr-068735	Neurospora crassa	26.39	2.00e-03	38.50
IUUC-Nle-070053	Nomascus leucogenys	50.46	0.00e+00	911.00
IUUC-Opr-070588	Ochotona princeps	49.23	0.00e+00	869.00
IUUC-Ont-072655	Oreochromis niloticus	45.44	0.00e+00	646.00
IUUC-Oan-073351	Ornithorhynchus anatinus	50.47	0.00e+00	934.00
IUUC-Ocu-074465	Oryctolagus cuniculus	50.92	0.00e+00	889.00
IUUC-Oba-075140	Oryza barthii	43.18	5.00e-04	38.50
IUUC-Obr-076710	Oryza brachyantha	38.46	1.00e-03	38.90
IUUC-Ogl-077337	Oryza glaberrima	48.72	1.00e-03	37.00
IUUC-Ogu-078861	Oryza glumaepatula	43.18	5.00e-04	38.50
IUUC-Oin-079568	Oryza indica	48.72	6.00e-04	37.40
IUUC-Olo-080883	Oryza longistaminata	40.43	3.00e-04	37.40
IUUC-Ome-081984	Oryza meridionalis	40.82	7.60e-02	32.30
IUUC-Oni-082468	Oryza nivara	40.82	7.80e-02	32.30
IUUC-Opu-083155	Oryza punctata	51.22	3.00e-04	40.00
IUUC-Olu-087831	Ostreococcus lucimarinus	33.90	2.00e-68	254.00
IUUC-Oga-089088	Otolemur garnettii	51.40	0.00e+00	911.00
IUUC-Oar-089870	Ovis aries	51.08	0.00e+00	894.00
IUUC-Ptr-090957	Pan troglodytes	51.61	0.00e+00	928.00
IUUC-Pan-092632	Papio anubis	58.25	0.00e+00	875.00
IUUC-Psi-093035	Pelodiscus sinensis	61.08	0.00e+00	1136.00
IUUC-Pno-094870	Phaeosphaeria nodorum	28.57	3.00e-03	37.40
IUUC-Pfo-096902	Poecilia formosa	43.56	3.00e-174	605.00
IUUC-Pab-098206	Pongo abelii	58.58	0.00e+00	882.00
IUUC-Pop-098801	Populus trichocarpa	38.46	2.00e-04	41.60
IUUC-Pca-100238	Procavia capensis	47.52	0.00e+00	840.00
IUUC-Ppe-101748	Prunus persica	35.94	3.00e-03	37.40
IUUC-Pva-103182	Pteropus vampyrus	50.99	0.00e+00	908.00
IUUC-Pte-104033	Pyrenophora teres	33.85	3.00e-03	37.00
IUUC-Pyt-104599	Pyrenophora triticirepentis	33.85	3.00e-03	37.40
IUUC-Rno-105141	Rattus norvegicus	51.08	0.00e+00	941.00
IUUC-Sce-106341	Saccharomyces cerevisiae	29.07	4.00e-05	42.70
IUUC-Sha-106827	Sarcophilus harrisii	48.91	0.00e+00	900.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.94	2.00e-43	170.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.55	8.00e-43	168.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	27.63	4.40e-02	33.10
IUUC-Sly-111170	Solanum lycopersicum	39.06	1.80e-02	33.90
IUUC-Sre-115025	Sporisorium reilianum	31.75	1.00e-36	148.00
IUUC-Ssc-116188	Sus scrofa	58.27	0.00e+00	791.00
IUUC-Tgu-116612	Taeniopygia guttata	73.47	0.00e+00	751.00
IUUC-Tsy-119560	Tarsius syrichta	50.81	5.00e-68	252.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.20	0.00e+00	636.00
IUUC-Tca-121338	Theobroma cacao	37.50	1.00e-03	38.90
IUUC-Tre-122089	Trichoderma reesei	30.11	1.00e-04	41.60
IUUC-Tae-125683	Triticum aestivum	41.67	9.00e-05	41.60
IUUC-Tme-127009	Tuber melanosporum	25.00	1.00e-03	38.90
IUUC-Tbe-127431	Tupaia belangeri	50.59	0.00e+00	860.00
IUUC-Ttr-128744	Tursiops truncatus	48.81	0.00e+00	862.00
IUUC-Uma-129536	Ustilago maydis	30.59	2.00e-37	150.00
IUUC-Vpa-130123	Vicugna pacos	81.08	1.00e-33	137.00
IUUC-Vvi-131025	Vitis vinifera	39.06	5.00e-04	40.00
IUUC-Xtr-132902	Xenopus tropicalis	47.37	0.00e+00	839.00
IUUC-Xma-133978	Xiphophorus maculatus	43.34	2.00e-147	515.00
IUUC-Zma-135480	Zea mays	40.00	6.00e-04	40.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence