iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007931

Ensembl Protein ID

AAS53198

UniProt Accession

Q755J9; VPS27_ASHGO

Genbank Protein ID

AAS53198.1

Protein Name

Vacuolar protein sorting-associated protein 27

Genbank Nucleotide ID

AE016819

Gene Name

VPS27; AFL176C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFL176C	AAS53198	AAS53198

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	29.86	2.00e-25	114.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	30.24	3.00e-25	114.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	30.43	2.00e-25	115.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	30.43	2.00e-25	115.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	30.33	9.00e-26	115.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	30.33	2.00e-25	114.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	50.32	2.00e-134	474.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	35.71	7.00e-65	243.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ashbya gossypii

Functional Description
(View)

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.

Protein Sequence
(Fasta)

MNTEIQTVAA LGECIQRATS ESIPNGEIDL ALALDVSDAV RSRRLGARDS MRALKKRVLQ 60
TKSNPNTQLA AWRLVEVCVK NGGTHFLKEV CSREFMDCME HVAAQEKTVD NEDLVQLCRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATACGG AAATCCAGAC AGTAGCGGCG CTGGGGGAAT GCATCCAGCG GGCGACAAGC 60
GAAAGCATAC CGAACGGGGA GATCGATCTT GCACTCGCGC TGGACGTGTC GGATGCAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF02809--UIM
PF00790--VHS

SMART

SM00064--FYVE
SM00726--UIM
SM00288--VHS

Gene Ontology

GO:0010008--C:endosome membrane
GO:0033565--C:ESCRT-0 complex
GO:0046872--F:metal ion binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:1904669--P:ATP export
GO:0045324--P:late endosome to vacuole transport
GO:0045053--P:protein retention in Golgi apparatus
GO:0006623--P:protein targeting to vacuole

KEGG

ago:AGOS_AFL176C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001175	Aegilops tauschii	41.94	7.00e-13	65.50
IUUC-Aml-001518	Ailuropoda melanoleuca	30.30	5.00e-27	114.00
IUUC-Atr-002790	Amborella trichopoda	50.85	3.00e-15	75.50
IUUC-Apl-003662	Anas platyrhynchos	32.45	5.00e-25	107.00
IUUC-Aca-004940	Anolis carolinensis	32.21	7.00e-28	116.00
IUUC-Aly-006019	Arabidopsis lyrata	47.37	1.00e-13	70.50
IUUC-Ath-006781	Arabidopsis thaliana	50.88	8.00e-15	73.90
IUUC-Acl-008274	Aspergillus clavatus	34.49	2.00e-73	268.00
IUUC-Afl-008521	Aspergillus flavus	32.60	2.00e-75	275.00
IUUC-Afu-008774	Aspergillus fumigatus	35.33	1.00e-73	268.00
IUUC-Ani-009445	Aspergillus nidulans	34.92	4.00e-75	273.00
IUUC-Ang-009863	Aspergillus niger	36.23	2.00e-74	271.00
IUUC-Ate-010444	Aspergillus terreus	36.72	6.00e-71	259.00
IUUC-Ame-011111	Astyanax mexicanus	31.70	9.00e-28	116.00
IUUC-Bgr-012087	Blumeria graminis	36.03	1.00e-72	265.00
IUUC-Bta-012506	Bos taurus	29.86	5.00e-27	114.00
IUUC-Bci-013782	Botrytis cinerea	32.33	1.00e-70	259.00
IUUC-Bdi-014708	Brachypodium distachyon	35.35	2.00e-12	65.90
IUUC-Bol-015456	Brassica oleracea	50.88	2.00e-15	75.90
IUUC-Bra-016882	Brassica rapa	50.91	9.00e-15	69.70
IUUC-Cel-018493	Caenorhabditis elegans	34.50	2.00e-29	122.00
IUUC-Cja-019998	Callithrix jacchus	30.33	1.00e-24	106.00
IUUC-Cfa-020615	Canis familiaris	30.33	3.00e-27	114.00
IUUC-Cpo-022019	Cavia porcellus	30.33	1.00e-27	115.00
IUUC-Csa-023596	Chlorocebus sabaeus	30.14	3.00e-27	114.00
IUUC-Cin-025488	Ciona intestinalis	30.45	6.00e-30	123.00
IUUC-Csv-025802	Ciona savignyi	30.14	7.00e-24	102.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	36.60	2.00e-71	261.00
IUUC-Cne-026847	Cryptococcus neoformans	33.25	2.00e-54	205.00
IUUC-Dre-028353	Danio rerio	31.36	6.00e-28	117.00
IUUC-Dno-029005	Dasypus novemcinctus	30.99	1.00e-26	113.00
IUUC-Dor-030280	Dipodomys ordii	30.33	1.00e-27	115.00
IUUC-Dse-031238	Dothistroma septosporum	34.90	5.00e-68	249.00
IUUC-Dme-031952	Drosophila melanogaster	30.24	1.00e-26	112.00
IUUC-Ete-032235	Echinops telfairi	30.59	3.00e-27	114.00
IUUC-Eca-033873	Equus caballus	30.43	1.00e-27	115.00
IUUC-Eeu-034820	Erinaceus europaeus	34.51	6.00e-17	80.10
IUUC-Fca-036563	Felis catus	30.33	2.00e-27	115.00
IUUC-Fal-036649	Ficedula albicollis	31.79	1.00e-25	109.00
IUUC-Fox-037962	Fusarium oxysporum	36.27	7.00e-66	243.00
IUUC-Fso-038396	Fusarium solani	34.76	4.00e-70	257.00
IUUC-Gmo-039510	Gadus morhua	32.27	2.00e-28	119.00
IUUC-Ggr-039938	Gaeumannomyces graminis	34.44	6.00e-66	243.00
IUUC-Gga-040201	Gallus gallus	31.73	2.00e-27	115.00
IUUC-Gac-041459	Gasterosteus aculeatus	32.27	2.00e-28	119.00
IUUC-Gma-042952	Glycine max	41.10	2.00e-16	77.00
IUUC-Ggo-044573	Gorilla gorilla	30.43	2.00e-27	115.00
IUUC-Hsa-046009	Homo sapiens	30.43	2.00e-27	115.00
IUUC-Hvu-047612	Hordeum vulgare	41.94	8.00e-13	65.50
IUUC-Itr-049065	Ictidomys tridecemlineatus	30.33	1.00e-27	116.00
IUUC-Kpa-049327	Komagataella pastoris	37.61	1.00e-78	285.00
IUUC-Lpe-051694	Leersia perrieri	37.23	3.00e-12	65.50
IUUC-Loc-051850	Lepisosteus oculatus	31.36	2.00e-26	112.00
IUUC-Lma-053252	Leptosphaeria maculans	36.56	2.00e-72	265.00
IUUC-Laf-053346	Loxodonta africana	30.81	2.00e-27	115.00
IUUC-Mcc-055789	Macaca mulatta	30.43	2.00e-27	115.00
IUUC-Meu-056329	Macropus eugenii	26.21	1.00e-17	82.80
IUUC-Mor-057205	Magnaporthe oryzae	34.87	6.00e-74	270.00
IUUC-Mpo-057295	Magnaporthe poae	33.95	4.00e-67	247.00
IUUC-Mtr-057931	Medicago truncatula	48.28	2.00e-14	72.80
IUUC-Mla-058849	Melampsora laricipopulina	36.73	3.00e-39	154.00
IUUC-Mga-059361	Meleagris gallopavo	31.73	2.00e-27	115.00
IUUC-Mvi-060561	Microbotryum violaceum	29.61	5.00e-45	173.00
IUUC-Mmr-061122	Microcebus murinus	30.33	3.00e-27	114.00
IUUC-Mdo-062171	Monodelphis domestica	30.28	2.00e-27	115.00
IUUC-Mmu-063952	Mus musculus	30.33	1.00e-27	116.00
IUUC-Mac-064661	Musa acuminata	47.46	2.00e-14	72.40
IUUC-Mpu-065852	Mustela putorius furo	30.33	2.00e-27	115.00
IUUC-Nfi-068539	Neosartorya fischeri	35.33	4.00e-74	270.00
IUUC-Ncr-068726	Neurospora crassa	34.56	9.00e-69	252.00
IUUC-Nle-070148	Nomascus leucogenys	26.94	1.00e-18	86.70
IUUC-Opr-070833	Ochotona princeps	37.84	6.00e-19	87.00
IUUC-Ont-071261	Oreochromis niloticus	31.25	4.00e-26	111.00
IUUC-Ocu-074133	Oryctolagus cuniculus	33.55	8.00e-18	83.60
IUUC-Oba-075700	Oryza barthii	44.07	8.00e-12	64.30
IUUC-Obr-076725	Oryza brachyantha	44.29	3.00e-07	46.60
IUUC-Ogl-077741	Oryza glaberrima	45.71	5.00e-06	42.70
IUUC-Ogu-078974	Oryza glumaepatula	45.71	7.00e-06	42.40
IUUC-Oin-079245	Oryza indica	45.71	5.00e-06	42.70
IUUC-Olo-080646	Oryza longistaminata	44.07	5.00e-12	64.70
IUUC-Ome-081286	Oryza meridionalis	45.71	2.00e-06	43.90
IUUC-Oni-082038	Oryza nivara	45.71	6.00e-06	42.40
IUUC-Opu-083654	Oryza punctata	45.71	5.00e-06	42.70
IUUC-Oru-084701	Oryza rufipogon	45.71	5.00e-06	42.70
IUUC-Osa-086159	Oryza sativa	45.71	5.00e-06	42.70
IUUC-Ola-087570	Oryzias latipes	30.77	3.00e-23	101.00
IUUC-Oga-089087	Otolemur garnettii	31.18	4.00e-25	107.00
IUUC-Oar-089534	Ovis aries	30.33	2.00e-27	115.00
IUUC-Ptr-091654	Pan troglodytes	28.50	2.00e-20	92.00
IUUC-Pan-092652	Papio anubis	30.43	2.00e-27	115.00
IUUC-Pno-095125	Phaeosphaeria nodorum	40.28	3.00e-56	211.00
IUUC-Ppa-095369	Physcomitrella patens	50.85	9.00e-16	75.10
IUUC-Pfo-096757	Poecilia formosa	33.52	1.00e-24	105.00
IUUC-Pab-097788	Pongo abelii	30.14	2.00e-27	115.00
IUUC-Pop-099314	Populus trichocarpa	34.91	1.00e-14	73.90
IUUC-Pca-100145	Procavia capensis	29.32	2.00e-19	88.60
IUUC-Ppe-101769	Prunus persica	50.94	4.00e-15	73.20
IUUC-Pva-102965	Pteropus vampyrus	31.46	1.00e-27	115.00
IUUC-Pgr-103609	Puccinia graminis	40.80	1.00e-39	155.00
IUUC-Ptt-103865	Puccinia triticina	41.79	1.00e-39	155.00
IUUC-Pte-104095	Pyrenophora teres	36.77	5.00e-69	253.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.39	3.00e-69	254.00
IUUC-Rno-105125	Rattus norvegicus	30.33	3.00e-27	114.00
IUUC-Sce-106192	Saccharomyces cerevisiae	42.34	2.00e-138	483.00
IUUC-Sha-107066	Sarcophilus harrisii	30.58	3.00e-27	114.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	34.48	3.00e-63	234.00
IUUC-Spo-108220	Schizosaccharomyces pombe	34.26	5.00e-70	256.00
IUUC-Ssl-108413	Sclerotinia sclerotiorum	39.73	6.00e-24	101.00
IUUC-Smo-109642	Selaginella moellendorffii	33.91	1.00e-15	74.70
IUUC-Sit-109755	Setaria italica	45.16	1.00e-14	71.20
IUUC-Sly-111265	Solanum lycopersicum	39.06	3.00e-05	39.30
IUUC-Stu-112464	Solanum tuberosum	51.72	1.00e-15	76.60
IUUC-Sar-113393	Sorex araneus	29.90	4.00e-18	84.30
IUUC-Sbi-114775	Sorghum bicolor	43.55	2.00e-13	67.00
IUUC-Sre-114986	Sporisorium reilianum	39.91	5.00e-47	180.00
IUUC-Ssc-115258	Sus scrofa	52.38	7.00e-17	80.50
IUUC-Tgu-117505	Taeniopygia guttata	31.73	3.00e-27	114.00
IUUC-Tru-118494	Takifugu rubripes	30.91	7.00e-27	113.00
IUUC-Tni-120174	Tetraodon nigroviridis	31.36	1.00e-27	116.00
IUUC-Tca-121043	Theobroma cacao	37.74	2.00e-15	76.30
IUUC-Tre-122191	Trichoderma reesei	32.81	2.00e-70	258.00
IUUC-Tvi-122318	Trichoderma virens	34.97	2.00e-74	271.00
IUUC-Tae-122898	Triticum aestivum	41.94	7.00e-13	65.50
IUUC-Tur-126023	Triticum urartu	41.94	8.00e-13	65.10
IUUC-Tme-126914	Tuber melanosporum	34.14	4.00e-69	253.00
IUUC-Tbe-127827	Tupaia belangeri	42.42	1.00e-12	68.60
IUUC-Ttr-129095	Tursiops truncatus	30.33	1.00e-27	115.00
IUUC-Uma-129475	Ustilago maydis	29.76	7.00e-55	206.00
IUUC-Vda-129908	Verticillium dahliae	37.46	2.00e-45	174.00
IUUC-Vvi-131456	Vitis vinifera	48.15	2.00e-04	37.40
IUUC-Xtr-131900	Xenopus tropicalis	31.46	2.00e-28	118.00
IUUC-Xma-133124	Xiphophorus maculatus	33.52	1.00e-24	106.00
IUUC-Yli-134682	Yarrowia lipolytica	37.04	3.00e-81	293.00
IUUC-Zma-135288	Zea mays	41.18	1.00e-13	68.20

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence