iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062369

UUCD1 version

UUC-MoD-00439

Ensembl Protein ID

ENSMODP00000000134.3

UniProt Accession

F6YBQ3; F6YBQ3_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000124.3	ENSMODT00000000138.3	ENSMODP00000000134.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	67.4	213	280
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.80e-07	28.4	312	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 213  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 280
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 312  PSNCLGIRAFADAQGCIELMKVAHSYT 338
           89***********************95 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSGSGRKDFD VKHILRLRWK LFSHPSSSPG GPAGGSCLQQ DSSGSFEHWG PSQSRLVKSQ 60
ERGSGGTFWK KSSSSSSSSS SSSSSSSSSS NPLNGTPTPA ATRLHQGLPG QSQQHSPRTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCATTGA AAGTAGGGCT TTGTATGCTG TATTTCATGT TTTACTAAAT GTCCAAATTT 60
GGCTAGACTA GACTTCATAT TTTTAGTGAG TTTATAACTA GATTGACTAT TGAGTGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

KEGG

mdo:100010015

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	93.99	0.00e+00	1320.00
IUUC-Apl-003408	Anas platyrhynchos	96.75	0.00e+00	1116.00
IUUC-Aca-004384	Anolis carolinensis	86.42	0.00e+00	1249.00
IUUC-Bta-012684	Bos taurus	98.28	0.00e+00	1132.00
IUUC-Bci-013875	Botrytis cinerea	27.84	1.00e-17	84.00
IUUC-Cja-019103	Callithrix jacchus	93.72	0.00e+00	1315.00
IUUC-Cfa-020670	Canis familiaris	96.43	0.00e+00	1175.00
IUUC-Cpo-021951	Cavia porcellus	98.46	0.00e+00	1138.00
IUUC-Csa-023607	Chlorocebus sabaeus	97.77	0.00e+00	1129.00
IUUC-Cho-024648	Choloepus hoffmanni	85.07	0.00e+00	1110.00
IUUC-Dno-029854	Dasypus novemcinctus	93.72	0.00e+00	1299.00
IUUC-Dor-030497	Dipodomys ordii	77.09	0.00e+00	961.00
IUUC-Eca-033525	Equus caballus	94.26	0.00e+00	1342.00
IUUC-Fca-035490	Felis catus	98.63	0.00e+00	1131.00
IUUC-Fal-037099	Ficedula albicollis	97.86	0.00e+00	1108.00
IUUC-Gga-041081	Gallus gallus	86.65	0.00e+00	1202.00
IUUC-Gma-043533	Glycine max	32.23	3.00e-38	153.00
IUUC-Ggo-044717	Gorilla gorilla	93.99	0.00e+00	1315.00
IUUC-Hsa-045726	Homo sapiens	93.99	0.00e+00	1315.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	94.39	0.00e+00	1323.00
IUUC-Loc-052321	Lepisosteus oculatus	77.33	0.00e+00	1103.00
IUUC-Laf-054378	Loxodonta africana	94.53	0.00e+00	1325.00
IUUC-Mcc-054985	Macaca mulatta	93.59	0.00e+00	1309.00
IUUC-Mmr-061255	Microcebus murinus	84.27	0.00e+00	1148.00
IUUC-Mmu-063334	Mus musculus	92.28	0.00e+00	1300.00
IUUC-Nle-069856	Nomascus leucogenys	94.13	0.00e+00	1317.00
IUUC-Ocu-074469	Oryctolagus cuniculus	94.13	0.00e+00	1316.00
IUUC-Obr-076181	Oryza brachyantha	31.80	4.00e-36	147.00
IUUC-Oin-080100	Oryza indica	29.51	3.00e-34	140.00
IUUC-Opu-083716	Oryza punctata	31.02	2.00e-32	134.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.78	3.00e-33	134.00
IUUC-Oga-088528	Otolemur garnettii	96.11	0.00e+00	1171.00
IUUC-Oar-089603	Ovis aries	98.12	0.00e+00	1127.00
IUUC-Ptr-090657	Pan troglodytes	93.59	0.00e+00	1310.00
IUUC-Psi-092962	Pelodiscus sinensis	96.57	0.00e+00	1117.00
IUUC-Pab-097812	Pongo abelii	93.46	0.00e+00	1286.00
IUUC-Pva-103042	Pteropus vampyrus	93.58	0.00e+00	1298.00
IUUC-Ssc-115880	Sus scrofa	98.45	0.00e+00	1133.00
IUUC-Tgu-116624	Taeniopygia guttata	95.37	0.00e+00	986.00
IUUC-Tsy-119339	Tarsius syrichta	86.38	0.00e+00	1177.00
IUUC-Tbe-127398	Tupaia belangeri	98.75	0.00e+00	675.00
IUUC-Ttr-129024	Tursiops truncatus	93.60	0.00e+00	1358.00
IUUC-Vpa-130515	Vicugna pacos	98.45	0.00e+00	1133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence