iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000017345.2	ENSPPYT00000033895.1	ENSPPYP00000024632.1
ENSPPYG00000017345.2	ENSPPYT00000020203.1	ENSPPYP00000019436.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-81	274.0	31	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC+ N++LQcL+ +p+l++++l+ ++++++++     +  ++++++q  +++ +++   +++p  +++ ++++a++f+  +q
   Q: 31   GLQNLGNTCFANAALQCLTYTPPLANYMLShEHSKTCHA-----EGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQ 114
           9*****************************445555544.....578****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+ +++ + +++ ++l+ ++F+g l+s++kcl+c+ vs +++p ld++l+++ 
   Q: 115  EDAHEFLQYTVDAMQKAC------------------LNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKA 185
           ******************..................3344567789999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+f+k+e+l+gen y+c+kckk + a+k++++++ ++vL+l LkRf    ++    ki k v++p+ Ld++p++++
   Q: 186  AQ-----SVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIRPYMSQ 265
           **.....9***************************************************....668889******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           p+ +   +  Y L+av+vH+G +++ GHY++y+k ++g W++++Ds V++++  +vl+   ++aYvlfY r
   Q: 266  PNGE---PIVYVLYAVLVHTGfNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLS---QQAYVLFYIR 330
           9977...8**************************************************...********87 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

LGDGIAPPQK VLFPSEKICL KWQQTHRVGA GLQNLGNTCF ANAALQCLTY TPPLANYMLS 60
HEHSKTCHAE GFCMMCTMQA HITQALSNPG DVIKPMFVIN EMRRIARHFR FGNQEDAHEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAGCTTCA GTATGCAAAG CTTGGTTTCT GACTCTTTCT TATTTTTCTA GCCCTAGGTG 60
ATGGCATCGC TCCTCCACAG AAAGTTCTTT TCCCATCTGA GAAGATTTGT CTTAAGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000401	Aegilops tauschii	39.21	6.00e-71	262.00
IUUC-Aml-002303	Ailuropoda melanoleuca	73.85	0.00e+00	1395.00
IUUC-Atr-003102	Amborella trichopoda	46.91	3.00e-85	310.00
IUUC-Apl-003459	Anas platyrhynchos	57.12	0.00e+00	708.00
IUUC-Aca-004440	Anolis carolinensis	69.04	0.00e+00	879.00
IUUC-Aly-006389	Arabidopsis lyrata	42.36	3.00e-76	280.00
IUUC-Ath-006710	Arabidopsis thaliana	42.36	3.00e-76	280.00
IUUC-Ago-007836	Ashbya gossypii	26.44	3.00e-34	140.00
IUUC-Ame-011358	Astyanax mexicanus	74.81	0.00e+00	659.00
IUUC-Bta-012803	Bos taurus	70.59	0.00e+00	1468.00
IUUC-Bol-015996	Brassica oleracea	38.93	4.00e-82	299.00
IUUC-Cja-019199	Callithrix jacchus	91.06	0.00e+00	1912.00
IUUC-Cfa-020597	Canis familiaris	75.00	0.00e+00	1535.00
IUUC-Cpo-021945	Cavia porcellus	69.82	0.00e+00	1444.00
IUUC-Csa-023485	Chlorocebus sabaeus	95.55	0.00e+00	1993.00
IUUC-Cho-024575	Choloepus hoffmanni	76.38	0.00e+00	986.00
IUUC-Dre-028442	Danio rerio	67.67	0.00e+00	651.00
IUUC-Dno-029673	Dasypus novemcinctus	73.95	0.00e+00	1598.00
IUUC-Dor-030518	Dipodomys ordii	64.45	7.00e-133	468.00
IUUC-Ete-033088	Echinops telfairi	58.40	0.00e+00	937.00
IUUC-Eca-033579	Equus caballus	73.12	0.00e+00	1533.00
IUUC-Eeu-034511	Erinaceus europaeus	54.71	0.00e+00	933.00
IUUC-Fca-035792	Felis catus	73.21	0.00e+00	1431.00
IUUC-Fal-037075	Ficedula albicollis	58.11	0.00e+00	741.00
IUUC-Gga-040504	Gallus gallus	55.96	0.00e+00	713.00
IUUC-Gma-044075	Glycine max	47.88	8.00e-85	308.00
IUUC-Ggo-044798	Gorilla gorilla	93.84	0.00e+00	1895.00
IUUC-Hsa-046072	Homo sapiens	96.84	0.00e+00	1982.00
IUUC-Hvu-047620	Hordeum vulgare	41.25	9.00e-74	271.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	76.12	0.00e+00	1657.00
IUUC-Lch-049867	Latimeria chalumnae	68.63	0.00e+00	859.00
IUUC-Loc-052621	Lepisosteus oculatus	68.75	0.00e+00	669.00
IUUC-Laf-054330	Loxodonta africana	92.34	0.00e+00	1196.00
IUUC-Mcc-054900	Macaca mulatta	99.49	0.00e+00	797.00
IUUC-Mga-059501	Meleagris gallopavo	41.58	0.00e+00	712.00
IUUC-Mvi-060547	Microbotryum violaceum	45.62	1.00e-80	293.00
IUUC-Mmr-060864	Microcebus murinus	74.96	0.00e+00	1622.00
IUUC-Mdo-062395	Monodelphis domestica	60.76	0.00e+00	1323.00
IUUC-Mmu-064236	Mus musculus	67.41	0.00e+00	1383.00
IUUC-Mpu-065822	Mustela putorius furo	75.68	0.00e+00	1559.00
IUUC-Mlu-067091	Myotis lucifugus	71.69	0.00e+00	1462.00
IUUC-Nle-069004	Nomascus leucogenys	95.87	0.00e+00	2022.00
IUUC-Opr-071170	Ochotona princeps	62.81	0.00e+00	1143.00
IUUC-Ont-071832	Oreochromis niloticus	67.83	0.00e+00	633.00
IUUC-Oan-073711	Ornithorhynchus anatinus	57.36	0.00e+00	1194.00
IUUC-Ocu-074596	Oryctolagus cuniculus	97.57	0.00e+00	914.00
IUUC-Oga-088641	Otolemur garnettii	74.22	0.00e+00	1586.00
IUUC-Oar-089760	Ovis aries	67.62	0.00e+00	1375.00
IUUC-Ptr-091445	Pan troglodytes	97.17	0.00e+00	2038.00
IUUC-Pan-092484	Papio anubis	95.47	0.00e+00	1911.00
IUUC-Psi-093277	Pelodiscus sinensis	52.99	0.00e+00	1010.00
IUUC-Pma-094651	Petromyzon marinus	39.38	1.00e-54	206.00
IUUC-Pfo-096469	Poecilia formosa	74.01	0.00e+00	633.00
IUUC-Ppe-101678	Prunus persica	46.25	4.00e-82	299.00
IUUC-Pva-103238	Pteropus vampyrus	66.99	0.00e+00	1328.00
IUUC-Rno-105068	Rattus norvegicus	67.30	0.00e+00	1392.00
IUUC-Sha-106713	Sarcophilus harrisii	61.53	0.00e+00	1347.00
IUUC-Smo-108763	Selaginella moellendorffii	48.05	1.00e-80	293.00
IUUC-Sar-113340	Sorex araneus	81.50	0.00e+00	1004.00
IUUC-Tgu-117149	Taeniopygia guttata	46.29	0.00e+00	818.00
IUUC-Tru-117776	Takifugu rubripes	67.70	7.00e-174	604.00
IUUC-Tsy-118974	Tarsius syrichta	75.18	0.00e+00	1597.00
IUUC-Tni-120774	Tetraodon nigroviridis	68.22	3.00e-173	601.00
IUUC-Tca-120936	Theobroma cacao	40.15	4.00e-85	309.00
IUUC-Ttr-128764	Tursiops truncatus	63.08	0.00e+00	1239.00
IUUC-Vvi-131535	Vitis vinifera	46.35	1.00e-86	315.00
IUUC-Xtr-132544	Xenopus tropicalis	58.56	2.00e-178	618.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence