iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020133

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006669

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000018800.3	ENSCAFT00000029849.3	ENSCAFP00000027741.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.30e-06	25.9	15	72
E3 activity/RING/RING	2.80e-06	28.1	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
            +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 15   RLLCPLCGKPMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 72
           689*************999*****************99*********99999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLSLA IRCIHSEEGC RWSGPLRHLQ SHLNTCSFNV IPCPNRCPTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGGCT TCGACTACAA GTTCCTGGAG AAGCCCAAGC GGCGGCTGCT GTGCCCGCTG 60
TGCGGGAAGC CCATGCGCGA GCCTGTGCAG GTCTCTACCT GCGGCCACCG CTTCTGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	42.25	1.00e-08	54.30
IUUC-Aml-001287	Ailuropoda melanoleuca	90.83	0.00e+00	835.00
IUUC-Ame-011530	Astyanax mexicanus	72.77	0.00e+00	712.00
IUUC-Bta-013582	Bos taurus	91.06	0.00e+00	848.00
IUUC-Bdi-014617	Brachypodium distachyon	24.46	3.00e-06	48.10
IUUC-Cpo-022021	Cavia porcellus	90.43	0.00e+00	846.00
IUUC-Csa-023199	Chlorocebus sabaeus	90.64	0.00e+00	847.00
IUUC-Dre-028193	Danio rerio	72.34	0.00e+00	710.00
IUUC-Dno-028917	Dasypus novemcinctus	91.06	0.00e+00	849.00
IUUC-Ete-032433	Echinops telfairi	89.79	0.00e+00	839.00
IUUC-Fca-036155	Felis catus	92.13	0.00e+00	856.00
IUUC-Gmo-038860	Gadus morhua	72.34	0.00e+00	707.00
IUUC-Gga-041052	Gallus gallus	78.09	0.00e+00	746.00
IUUC-Gac-041489	Gasterosteus aculeatus	72.13	0.00e+00	703.00
IUUC-Ggo-044996	Gorilla gorilla	90.43	0.00e+00	842.00
IUUC-Hsa-046252	Homo sapiens	90.64	0.00e+00	845.00
IUUC-Hvu-047127	Hordeum vulgare	38.03	1.00e-07	50.40
IUUC-Itr-048232	Ictidomys tridecemlineatus	90.85	0.00e+00	848.00
IUUC-Kpa-049340	Komagataella pastoris	26.91	9.00e-16	78.20
IUUC-Lpe-051100	Leersia perrieri	40.32	8.00e-08	51.20
IUUC-Loc-052312	Lepisosteus oculatus	73.04	0.00e+00	708.00
IUUC-Laf-054376	Loxodonta africana	91.28	0.00e+00	851.00
IUUC-Mcc-055684	Macaca mulatta	90.64	0.00e+00	847.00
IUUC-Mmr-061198	Microcebus murinus	90.85	0.00e+00	847.00
IUUC-Mdo-062585	Monodelphis domestica	81.28	0.00e+00	773.00
IUUC-Mmu-064303	Mus musculus	90.00	0.00e+00	844.00
IUUC-Mpu-066854	Mustela putorius furo	92.34	0.00e+00	859.00
IUUC-Nle-070098	Nomascus leucogenys	89.36	0.00e+00	832.00
IUUC-Ont-071518	Oreochromis niloticus	72.28	0.00e+00	704.00
IUUC-Ocu-073841	Oryctolagus cuniculus	90.64	0.00e+00	847.00
IUUC-Oba-075263	Oryza barthii	38.71	4.00e-07	48.50
IUUC-Obr-076500	Oryza brachyantha	40.85	2.00e-08	53.10
IUUC-Ogl-077708	Oryza glaberrima	38.71	4.00e-07	48.50
IUUC-Ogu-078582	Oryza glumaepatula	38.71	4.00e-07	48.90
IUUC-Oin-079499	Oryza indica	38.71	4.00e-07	48.50
IUUC-Ome-081269	Oryza meridionalis	40.32	9.00e-08	51.20
IUUC-Oni-083040	Oryza nivara	40.32	1.00e-07	50.10
IUUC-Opu-083468	Oryza punctata	40.32	7.00e-08	51.60
IUUC-Oru-084662	Oryza rufipogon	38.71	7.00e-07	48.50
IUUC-Osa-085740	Oryza sativa	38.71	6.00e-07	48.10
IUUC-Ola-086674	Oryzias latipes	72.71	0.00e+00	706.00
IUUC-Oga-088510	Otolemur garnettii	90.64	0.00e+00	846.00
IUUC-Oar-089225	Ovis aries	87.23	0.00e+00	804.00
IUUC-Pan-092725	Papio anubis	90.64	0.00e+00	847.00
IUUC-Pfo-096341	Poecilia formosa	72.07	0.00e+00	705.00
IUUC-Ppe-101708	Prunus persica	31.19	3.00e-07	51.60
IUUC-Pva-103131	Pteropus vampyrus	87.02	2.00e-122	432.00
IUUC-Rno-105996	Rattus norvegicus	90.21	0.00e+00	844.00
IUUC-Sit-110103	Setaria italica	26.23	1.00e-05	45.40
IUUC-Sly-111800	Solanum lycopersicum	30.83	1.00e-06	49.30
IUUC-Sbi-113900	Sorghum bicolor	38.03	3.00e-07	49.30
IUUC-Tru-117602	Takifugu rubripes	72.77	0.00e+00	714.00
IUUC-Tur-126067	Triticum urartu	42.25	1.00e-08	54.30
IUUC-Ttr-128370	Tursiops truncatus	92.25	0.00e+00	682.00
IUUC-Vvi-131592	Vitis vinifera	31.19	8.00e-07	50.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence