iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003987.5	ENSGALT00000006350.5	ENSGALP00000006340.5
ENSGALG00000003987.5	ENSGALT00000054763.1	ENSGALP00000052535.1
ENSGALG00000003987.5	ENSGALT00000055256.1	ENSGALP00000046441.1
ENSGALG00000003987.5	ENSGALT00000048056.1	ENSGALP00000053878.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.20e-07	30.5	18	56
E3 activity/RING/U-box	8.90e-06	26.1	16	73

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  +++++++v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVRVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           **********9***************999.....89*******6 PP

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlr 62
            lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l 
   Q: 16   VLCPLCGKPMREPVRVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELE 73
           58***************9*****************99**********99999998876 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPGYDYKLLE RPRRRVLCPL CGKPMREPVR VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEAQVLSLA IRCIHSEEGC RWSGLIRHLQ AHLGTCGFNV IPCPNRCSTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGGCT ACGACTACAA ACTGCTGGAG CGGCCGCGGC GGAGAGTGCT GTGCCCGCTG 60
TGCGGGAAGC CCATGCGGGA GCCCGTGCGG GTCTCCACCT GCGGACACCG CTTCTGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00917--MATH
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	82.09	0.00e+00	795.00
IUUC-Ame-011530	Astyanax mexicanus	81.49	0.00e+00	813.00
IUUC-Bta-013582	Bos taurus	81.06	0.00e+00	798.00
IUUC-Cfa-020133	Canis familiaris	78.09	0.00e+00	746.00
IUUC-Cpo-022021	Cavia porcellus	80.85	0.00e+00	797.00
IUUC-Csa-023199	Chlorocebus sabaeus	80.85	0.00e+00	797.00
IUUC-Dre-028193	Danio rerio	82.34	0.00e+00	816.00
IUUC-Dno-028917	Dasypus novemcinctus	81.70	0.00e+00	804.00
IUUC-Dse-031478	Dothistroma septosporum	24.48	2.00e-10	60.80
IUUC-Ete-032433	Echinops telfairi	80.64	0.00e+00	791.00
IUUC-Fca-036155	Felis catus	82.34	0.00e+00	806.00
IUUC-Gmo-038860	Gadus morhua	80.64	0.00e+00	800.00
IUUC-Gac-041489	Gasterosteus aculeatus	81.91	0.00e+00	808.00
IUUC-Ggo-044996	Gorilla gorilla	80.64	0.00e+00	793.00
IUUC-Hsa-046252	Homo sapiens	80.85	0.00e+00	795.00
IUUC-Hvu-047095	Hordeum vulgare	24.82	1.00e-06	48.90
IUUC-Itr-048232	Ictidomys tridecemlineatus	81.28	0.00e+00	800.00
IUUC-Kpa-049340	Komagataella pastoris	26.91	2.00e-14	73.60
IUUC-Loc-052312	Lepisosteus oculatus	81.32	0.00e+00	809.00
IUUC-Laf-054376	Loxodonta africana	81.49	0.00e+00	802.00
IUUC-Mcc-055684	Macaca mulatta	80.85	0.00e+00	797.00
IUUC-Mmr-061198	Microcebus murinus	81.28	0.00e+00	800.00
IUUC-Mdo-062585	Monodelphis domestica	79.57	0.00e+00	781.00
IUUC-Mmu-064303	Mus musculus	81.49	0.00e+00	805.00
IUUC-Mpu-066854	Mustela putorius furo	82.13	0.00e+00	806.00
IUUC-Nle-070098	Nomascus leucogenys	79.79	0.00e+00	785.00
IUUC-Ont-071518	Oreochromis niloticus	82.52	0.00e+00	810.00
IUUC-Ocu-073841	Oryctolagus cuniculus	80.85	0.00e+00	796.00
IUUC-Obr-076500	Oryza brachyantha	37.14	4.00e-08	52.00
IUUC-Ola-086674	Oryzias latipes	82.52	0.00e+00	809.00
IUUC-Oga-088510	Otolemur garnettii	81.06	0.00e+00	798.00
IUUC-Oar-089225	Ovis aries	77.87	0.00e+00	756.00
IUUC-Pan-092725	Papio anubis	80.85	0.00e+00	797.00
IUUC-Pfo-096341	Poecilia formosa	82.09	0.00e+00	809.00
IUUC-Ppe-101708	Prunus persica	27.50	7.00e-07	50.10
IUUC-Pva-103131	Pteropus vampyrus	78.24	7.00e-119	420.00
IUUC-Rno-105996	Rattus norvegicus	81.70	0.00e+00	805.00
IUUC-Sly-111800	Solanum lycopersicum	28.33	6.00e-06	47.00
IUUC-Tru-117602	Takifugu rubripes	82.34	0.00e+00	812.00
IUUC-Tae-123531	Triticum aestivum	24.09	2.00e-06	48.50
IUUC-Ttr-128370	Tursiops truncatus	80.75	4.00e-180	623.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence