iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072922

UUCD1 version

UUC-OrA-00813

Ensembl Protein ID

ENSOANP00000017814.2

UniProt Accession

F7DYW4; F7DYW4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011244.2	ENSOANT00000017817.2	ENSOANP00000017814.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	7.20e-45	153.0	40	229

Active Site

Position(s)	Description	Evidence
47	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
50	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
223		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
            ++ktkgDGnC++rA++++                                                          ll+vf+d+s sd
   Q: 40   SVRKTKGDGNCFYRALGFAylesllgndreilrfkelllktpndlisagfeepkfrsffvafcsaveslekdssvssLLKVFNDQSYSD 128
           579************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
            +v++Lr+lt++++++++dff++f++e++d+k+fc ++vep+a+ +++++i+aL+ +L++p++v++vd+ +    g+l++++fpe++  
   Q: 129  RIVQFLRLLTAAFIKNRADFFRHFVDEEMDVKDFCAQEVEPMATeCDHVQITALSRALNIPLQVEYVDEAD----GALNHHVFPEAA-S 212
           **********************************************************************8....9***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+ +HY++L+a
   Q: 213  PSVYLLYKASHYNILYA 229
           ***************97 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MQPSFNLISE KCDILSILNE HPENRIYQRK IQELSKRFTS VRKTKGDGNC FYRALGFAYL 60
ESLLGNDREI LRFKELLLKT PNDLISAGFE EPKFRSFFVA FCSAVESLEK DSSVSSLLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGGGCGCT AACCTGTTGT TGGCCGGGCG GGCGGGAGGG AGGTTTCTTT CCTACTTCGG 60
CCCGGACCTG CCTGTGGTTA CTTCGCTCGC CCTTCCGCTC GCCCGTCGGG GAGAGACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043130--F:ubiquitin binding
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

KEGG

oaa:100080307

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	82.53	1.00e-113	401.00
IUUC-Apl-003233	Anas platyrhynchos	27.69	3.00e-05	38.90
IUUC-Aca-004648	Anolis carolinensis	44.93	5.00e-55	206.00
IUUC-Aly-005710	Arabidopsis lyrata	36.43	4.00e-35	140.00
IUUC-Ath-007112	Arabidopsis thaliana	36.29	6.00e-35	140.00
IUUC-Ago-007724	Ashbya gossypii	30.14	2.00e-01	31.60
IUUC-Afl-008439	Aspergillus flavus	34.15	7.00e-06	43.50
IUUC-Ame-010740	Astyanax mexicanus	47.58	2.00e-61	228.00
IUUC-Bta-012766	Bos taurus	82.97	6.00e-114	402.00
IUUC-Bol-016100	Brassica oleracea	36.68	6.00e-34	137.00
IUUC-Bra-017705	Brassica rapa	35.77	7.00e-32	130.00
IUUC-Cel-018295	Caenorhabditis elegans	31.73	2.00e-28	119.00
IUUC-Cja-019480	Callithrix jacchus	81.66	2.00e-112	397.00
IUUC-Cfa-021106	Canis familiaris	82.53	2.00e-113	400.00
IUUC-Cpo-022187	Cavia porcellus	81.66	4.00e-112	396.00
IUUC-Cre-022997	Chlamydomonas reinhardtii	34.75	2.00e-32	131.00
IUUC-Csa-023493	Chlorocebus sabaeus	81.22	1.00e-111	394.00
IUUC-Cho-024411	Choloepus hoffmanni	65.20	1.00e-70	258.00
IUUC-Cin-025507	Ciona intestinalis	39.13	1.00e-29	121.00
IUUC-Csv-026273	Ciona savignyi	39.46	2.00e-43	168.00
IUUC-Dre-027843	Danio rerio	46.70	4.00e-62	230.00
IUUC-Dno-029346	Dasypus novemcinctus	84.28	6.00e-115	405.00
IUUC-Dor-031012	Dipodomys ordii	82.53	2.00e-113	400.00
IUUC-Dme-031922	Drosophila melanogaster	36.24	2.00e-44	171.00
IUUC-Ete-032266	Echinops telfairi	75.55	2.00e-102	364.00
IUUC-Eca-033356	Equus caballus	82.53	3.00e-112	397.00
IUUC-Eeu-034775	Erinaceus europaeus	82.10	2.00e-112	397.00
IUUC-Fca-035363	Felis catus	82.10	1.00e-112	397.00
IUUC-Gmo-038908	Gadus morhua	45.09	3.00e-57	214.00
IUUC-Ggr-040020	Gaeumannomyces graminis	28.51	3.00e-19	89.70
IUUC-Gga-040460	Gallus gallus	43.75	1.00e-54	205.00
IUUC-Gac-042417	Gasterosteus aculeatus	45.09	3.00e-58	217.00
IUUC-Gma-043712	Glycine max	36.68	2.00e-34	139.00
IUUC-Ggo-045023	Gorilla gorilla	81.94	1.00e-111	394.00
IUUC-Hsa-046984	Homo sapiens	81.22	1.00e-111	394.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	82.53	1.00e-112	397.00
IUUC-Lch-050514	Latimeria chalumnae	57.78	5.00e-81	293.00
IUUC-Loc-052003	Lepisosteus oculatus	49.55	5.00e-62	229.00
IUUC-Laf-054382	Loxodonta africana	84.72	6.00e-115	405.00
IUUC-Mcc-055516	Macaca mulatta	81.22	8.00e-112	395.00
IUUC-Meu-056038	Macropus eugenii	83.60	1.00e-92	331.00
IUUC-Mtr-057712	Medicago truncatula	34.26	5.00e-30	124.00
IUUC-Mvi-060358	Microbotryum violaceum	36.22	5.00e-11	60.80
IUUC-Mmr-060918	Microcebus murinus	83.41	3.00e-114	403.00
IUUC-Mdo-062638	Monodelphis domestica	84.05	5.00e-115	405.00
IUUC-Mmu-063973	Mus musculus	85.02	3.00e-113	400.00
IUUC-Mac-065274	Musa acuminata	33.63	1.00e-25	109.00
IUUC-Mpu-066013	Mustela putorius furo	82.10	4.00e-113	399.00
IUUC-Mlu-067509	Myotis lucifugus	80.35	4.00e-109	386.00
IUUC-Nle-069673	Nomascus leucogenys	81.22	1.00e-111	394.00
IUUC-Opr-070761	Ochotona princeps	73.17	6.00e-67	245.00
IUUC-Ont-071901	Oreochromis niloticus	44.64	2.00e-57	214.00
IUUC-Ocu-074643	Oryctolagus cuniculus	82.53	3.00e-113	399.00
IUUC-Oni-082026	Oryza nivara	28.96	3.00e-14	72.40
IUUC-Oru-084761	Oryza rufipogon	28.96	3.00e-14	72.40
IUUC-Ola-086603	Oryzias latipes	46.30	5.00e-50	189.00
IUUC-Oga-088936	Otolemur garnettii	82.10	2.00e-112	397.00
IUUC-Oar-089460	Ovis aries	82.97	9.00e-114	402.00
IUUC-Ptr-090805	Pan troglodytes	80.79	3.00e-111	393.00
IUUC-Pan-091969	Papio anubis	81.22	1.00e-111	394.00
IUUC-Psi-093823	Pelodiscus sinensis	44.93	7.00e-56	209.00
IUUC-Pma-094366	Petromyzon marinus	45.78	3.00e-57	214.00
IUUC-Pfo-096734	Poecilia formosa	43.75	2.00e-51	194.00
IUUC-Pab-098476	Pongo abelii	81.66	6.00e-112	395.00
IUUC-Pop-099401	Populus trichocarpa	35.29	6.00e-33	133.00
IUUC-Pca-100252	Procavia capensis	81.25	4.00e-44	170.00
IUUC-Ppe-101977	Prunus persica	36.24	4.00e-34	138.00
IUUC-Pva-102204	Pteropus vampyrus	81.22	7.00e-112	395.00
IUUC-Pgr-103552	Puccinia graminis	55.17	2.20e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	84.28	6.00e-115	405.00
IUUC-Sha-106968	Sarcophilus harrisii	84.65	2.00e-114	404.00
IUUC-Sly-111640	Solanum lycopersicum	36.75	1.00e-34	139.00
IUUC-Sar-113295	Sorex araneus	83.41	2.00e-112	397.00
IUUC-Ssc-115288	Sus scrofa	81.66	9.00e-112	395.00
IUUC-Tru-117664	Takifugu rubripes	44.54	4.00e-56	210.00
IUUC-Tni-120440	Tetraodon nigroviridis	39.91	8.00e-42	162.00
IUUC-Tca-121467	Theobroma cacao	36.52	2.00e-33	135.00
IUUC-Tbe-127717	Tupaia belangeri	79.59	8.00e-65	238.00
IUUC-Ttr-128221	Tursiops truncatus	66.38	3.00e-84	303.00
IUUC-Uma-129443	Ustilago maydis	34.78	8.00e-24	103.00
IUUC-Vvi-131389	Vitis vinifera	37.07	3.00e-34	138.00
IUUC-Xtr-131951	Xenopus tropicalis	52.94	3.00e-71	260.00
IUUC-Xma-134191	Xiphophorus maculatus	44.20	9.00e-52	196.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence