iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098476

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01222852

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000006094.2	ENSPPYT00000007204.2	ENSPPYP00000006930.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.60e-49	168.0	45	234

Active Site

Position(s)	Description	Evidence
52	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
55	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
228		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s+sd
   Q: 45   AIRKTKGDGNCFYRALGYSylesllgksreifkfkervlqtpndllaagfeehkfrnffnafysavelvekdgsvssLLKVFNDQSASD 133
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a+ +++i+i+aL+q+Ls++++v++vd++++    +l++++fpe++ +
   Q: 134  HIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATeCDHIQITALSQALSIALQVEYVDEMDT----ALNHHVFPEAA-T 217
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 218  PSVYLLYKTSHYNILYA 234
           ***************97 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

FPIFQSETSF NLISEKCDIL SILRDHPENR IYRRKIEELS KRFTAIRKTK GDGNCFYRAL 60
GYSYLESLLG KSREIFKFKE RVLQTPNDLL AAGFEEHKFR NFFNAFYSAV ELVEKDGSVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCCCTAT CTTTCAGAGT GAAACATCTT TCAACCTAAT ATCAGAAAAA TGTGACATTC 60
TATCCATTCT TCGGGACCAT CCTGAAAACA GGATTTACCG GAGGAAAATC GAGGTGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	94.85	2.00e-131	461.00
IUUC-Afl-008439	Aspergillus flavus	30.95	1.00e-04	40.00
IUUC-Bta-012766	Bos taurus	95.28	7.00e-131	459.00
IUUC-Cja-019480	Callithrix jacchus	96.14	1.00e-132	464.00
IUUC-Cfa-021106	Canis familiaris	95.28	3.00e-132	463.00
IUUC-Cpo-022187	Cavia porcellus	94.04	5.00e-131	459.00
IUUC-Csa-023493	Chlorocebus sabaeus	99.58	5.00e-140	489.00
IUUC-Cho-024411	Choloepus hoffmanni	74.63	5.00e-83	300.00
IUUC-Dno-029346	Dasypus novemcinctus	94.83	2.00e-130	457.00
IUUC-Dor-031012	Dipodomys ordii	94.85	1.00e-131	461.00
IUUC-Ete-032266	Echinops telfairi	85.34	5.00e-117	413.00
IUUC-Eca-033356	Equus caballus	96.14	1.00e-131	461.00
IUUC-Eeu-034775	Erinaceus europaeus	95.26	1.00e-130	458.00
IUUC-Fca-035363	Felis catus	93.56	2.00e-129	454.00
IUUC-Ggo-045023	Gorilla gorilla	99.14	5.00e-136	476.00
IUUC-Hsa-046984	Homo sapiens	99.57	1.00e-136	478.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	94.85	8.00e-132	462.00
IUUC-Lch-050514	Latimeria chalumnae	60.44	9.00e-83	299.00
IUUC-Loc-052003	Lepisosteus oculatus	49.34	3.00e-63	234.00
IUUC-Laf-054382	Loxodonta africana	94.42	3.00e-131	460.00
IUUC-Mcc-055516	Macaca mulatta	99.15	1.00e-136	478.00
IUUC-Meu-056038	Macropus eugenii	87.83	1.00e-98	351.00
IUUC-Mmr-060918	Microcebus murinus	95.71	5.00e-132	462.00
IUUC-Mdo-062638	Monodelphis domestica	89.22	5.00e-123	432.00
IUUC-Mmu-063973	Mus musculus	94.04	5.00e-131	460.00
IUUC-Mpu-066013	Mustela putorius furo	95.69	7.00e-132	462.00
IUUC-Mlu-067509	Myotis lucifugus	93.56	4.00e-128	449.00
IUUC-Nle-069673	Nomascus leucogenys	99.57	1.00e-136	478.00
IUUC-Opr-070761	Ochotona princeps	86.67	7.00e-80	288.00
IUUC-Oan-072922	Ornithorhynchus anatinus	81.66	9.00e-112	395.00
IUUC-Ocu-074643	Oryctolagus cuniculus	93.99	5.00e-130	456.00
IUUC-Oni-082026	Oryza nivara	28.32	8.00e-16	78.60
IUUC-Oru-084761	Oryza rufipogon	28.32	8.00e-16	78.60
IUUC-Ola-086603	Oryzias latipes	44.44	7.00e-51	193.00
IUUC-Oga-088936	Otolemur garnettii	95.30	4.00e-132	463.00
IUUC-Oar-089460	Ovis aries	95.34	1.00e-132	464.00
IUUC-Ptr-090805	Pan troglodytes	99.14	3.00e-136	476.00
IUUC-Pan-091969	Papio anubis	99.57	1.00e-136	478.00
IUUC-Pca-100252	Procavia capensis	89.00	1.00e-51	196.00
IUUC-Pva-102204	Pteropus vampyrus	93.99	8.00e-131	459.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.40e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	94.42	9.00e-131	458.00
IUUC-Sha-106968	Sarcophilus harrisii	89.22	2.00e-123	434.00
IUUC-Sar-113295	Sorex araneus	94.83	1.00e-128	451.00
IUUC-Ssc-115288	Sus scrofa	94.83	4.00e-130	456.00
IUUC-Tni-120440	Tetraodon nigroviridis	38.53	7.00e-42	163.00
IUUC-Tbe-127717	Tupaia belangeri	93.92	2.00e-77	280.00
IUUC-Ttr-128221	Tursiops truncatus	76.29	3.00e-99	353.00
IUUC-Uma-129443	Ustilago maydis	33.03	1.00e-24	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence