iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054167

UUCD1 version

UUC-LoA-01079

Ensembl Protein ID

ENSLAFP00000005048.2

UniProt Accession

G3SXC7; G3SXC7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006018.2	ENSLAFT00000006018.2	ENSLAFP00000005048.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-95	318.8	236	568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy. 87
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l++++ + +++ +  +++kl++ +w +s + +vsp+e++++++++a++f gy 
   Q: 236  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYLRDLSHSS-SAHTALMEVEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYk 323
           9*****************************87888888875.577777788**********889999*******************773 PP
   S: 88   .eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
            +qqDaqEfl+flld+l++e+++ +  pk++ e+ d+     +      ++k  ++++s i dlF gqlks+++c ec+  s+ ++pf+
   Q: 324  lSQQDAQEFLRFLLDGLHNEVNRVTVRPKSNPENLDRLPD--DekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTECGYCSTVFDPFW 410
           36*******************9955555555544443333..2235559**************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple. 258
           dlslp+ ++    + +l dc++ ftke+ l+g++k  c +c +++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ 
   Q: 411  DLSLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCGARKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVSFPLRd 496
           ********9976.779***************************************************..88899*************** PP
   S: 259  LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           Ldl++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 497  LDLREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpGTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 568
           ********9553....78*************************44555*******************...********8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA PYAKSGYGTY TPSTYGANLT ASFLEKEKLG FKPGPPSSFL 60
TRPRTYGPSS ILDYDRGRPL LRPDIGGSKR AESQTRGTEW ASGSGLSGGS GSDLVRDFSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC CCTGAAGCGC TACACAGAAT CGGCCCGCTA CACAGATGCC 60
CCTTACGCCA AATCAGGCTA CGGCACCTAC ACCCCCTCCA CGTATGGGGC CAACCTCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	88.18	0.00e+00	1014.00
IUUC-Aca-005132	Anolis carolinensis	59.57	0.00e+00	674.00
IUUC-Ame-011102	Astyanax mexicanus	74.29	3.00e-146	511.00
IUUC-Bta-012529	Bos taurus	85.39	0.00e+00	946.00
IUUC-Bol-015281	Brassica oleracea	35.45	1.00e-47	184.00
IUUC-Bra-016678	Brassica rapa	35.73	3.00e-49	189.00
IUUC-Cja-019016	Callithrix jacchus	83.50	0.00e+00	954.00
IUUC-Cfa-020714	Canis familiaris	87.68	0.00e+00	1034.00
IUUC-Cpo-021727	Cavia porcellus	83.55	0.00e+00	951.00
IUUC-Csa-023071	Chlorocebus sabaeus	96.29	0.00e+00	667.00
IUUC-Cin-025797	Ciona intestinalis	50.29	1.00e-95	342.00
IUUC-Csv-026132	Ciona savignyi	51.03	1.00e-96	347.00
IUUC-Dre-027872	Danio rerio	80.52	9.00e-165	572.00
IUUC-Dno-029329	Dasypus novemcinctus	86.51	0.00e+00	1030.00
IUUC-Dor-030574	Dipodomys ordii	86.70	0.00e+00	979.00
IUUC-Dme-032208	Drosophila melanogaster	45.94	4.00e-80	293.00
IUUC-Ete-032725	Echinops telfairi	78.07	3.00e-163	568.00
IUUC-Eca-033361	Equus caballus	88.18	0.00e+00	1013.00
IUUC-Eeu-035272	Erinaceus europaeus	94.59	1.00e-93	337.00
IUUC-Fca-036497	Felis catus	88.51	0.00e+00	1019.00
IUUC-Fal-036766	Ficedula albicollis	62.27	0.00e+00	652.00
IUUC-Gmo-039129	Gadus morhua	60.61	1.00e-123	435.00
IUUC-Gga-040889	Gallus gallus	83.01	6.00e-143	500.00
IUUC-Gac-042475	Gasterosteus aculeatus	68.95	3.00e-138	484.00
IUUC-Ggo-044814	Gorilla gorilla	90.88	7.00e-173	599.00
IUUC-Hsa-045937	Homo sapiens	86.02	0.00e+00	952.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	86.50	0.00e+00	1019.00
IUUC-Lch-050527	Latimeria chalumnae	59.54	0.00e+00	629.00
IUUC-Loc-052697	Lepisosteus oculatus	78.19	2.00e-163	568.00
IUUC-Lma-053021	Leptosphaeria maculans	33.95	1.00e-53	204.00
IUUC-Mcc-055584	Macaca mulatta	86.68	0.00e+00	996.00
IUUC-Meu-056542	Macropus eugenii	81.44	0.00e+00	889.00
IUUC-Mga-060020	Meleagris gallopavo	60.79	2.00e-177	615.00
IUUC-Mmr-060989	Microcebus murinus	87.68	0.00e+00	1001.00
IUUC-Mdo-062761	Monodelphis domestica	80.98	0.00e+00	884.00
IUUC-Mmu-063710	Mus musculus	84.08	0.00e+00	972.00
IUUC-Mpu-066573	Mustela putorius furo	88.34	0.00e+00	1017.00
IUUC-Nle-070013	Nomascus leucogenys	85.32	0.00e+00	927.00
IUUC-Opr-070907	Ochotona princeps	86.07	0.00e+00	949.00
IUUC-Ont-071944	Oreochromis niloticus	80.57	3.00e-166	577.00
IUUC-Oan-073105	Ornithorhynchus anatinus	77.19	2.00e-142	498.00
IUUC-Ocu-073941	Oryctolagus cuniculus	86.56	0.00e+00	989.00
IUUC-Ola-087412	Oryzias latipes	70.52	9.00e-157	546.00
IUUC-Oga-088973	Otolemur garnettii	87.52	0.00e+00	1002.00
IUUC-Oar-089916	Ovis aries	85.39	0.00e+00	1009.00
IUUC-Ptr-090998	Pan troglodytes	86.18	0.00e+00	957.00
IUUC-Pan-092686	Papio anubis	86.84	0.00e+00	998.00
IUUC-Psi-093284	Pelodiscus sinensis	70.40	2.00e-119	421.00
IUUC-Pma-094462	Petromyzon marinus	63.16	5.00e-70	256.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.32	5.00e-42	166.00
IUUC-Pfo-097352	Poecilia formosa	77.99	3.00e-170	591.00
IUUC-Pab-098688	Pongo abelii	79.77	0.00e+00	848.00
IUUC-Pca-100205	Procavia capensis	92.00	0.00e+00	656.00
IUUC-Pva-103188	Pteropus vampyrus	87.19	0.00e+00	966.00
IUUC-Pte-104348	Pyrenophora teres	34.27	5.00e-41	163.00
IUUC-Rno-105853	Rattus norvegicus	84.70	0.00e+00	1004.00
IUUC-Sha-107237	Sarcophilus harrisii	81.12	0.00e+00	890.00
IUUC-Sar-113103	Sorex araneus	89.43	1.00e-175	608.00
IUUC-Ssc-115955	Sus scrofa	87.68	0.00e+00	1000.00
IUUC-Tgu-116894	Taeniopygia guttata	69.68	2.00e-174	604.00
IUUC-Tru-117703	Takifugu rubripes	64.93	8.00e-129	453.00
IUUC-Tsy-118879	Tarsius syrichta	95.10	0.00e+00	822.00
IUUC-Tni-119866	Tetraodon nigroviridis	77.88	2.00e-155	541.00
IUUC-Tbe-127367	Tupaia belangeri	78.17	4.00e-175	607.00
IUUC-Ttr-128773	Tursiops truncatus	84.24	0.00e+00	978.00
IUUC-Vpa-130402	Vicugna pacos	76.11	0.00e+00	711.00
IUUC-Xtr-132658	Xenopus tropicalis	65.20	1.00e-171	596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence