iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012374

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02048465

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000013645.5	ENSBTAT00000018136.5	ENSBTAP00000018136.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.95	0.00e+00	633.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

PSSPCLWRQA SDLIMWATCC NWFCLDGQPE EASPPQGART QAYSNPGYSS FPSPTGSEPS 60
CKACGTHFAS MARKQTCLDC KKNFCTSCSS QVGAGPRLCL LCQRFRATDF RREELMKMKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTCCTCAC CTTGCCTCTG GCGGCAGGTG TAGACCTATA TGGCGGTTCA CCTGTGCCCG 60
CGGGGGTGGG AACCCAGTTG AGGTGTGTCT TTTTAATTCT GACCTTTCTC CCCTTTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	86.14	0.00e+00	632.00
IUUC-Apl-004124	Anas platyrhynchos	63.56	4.00e-117	414.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	2.00e-08	54.70
IUUC-Ame-011616	Astyanax mexicanus	58.89	7.00e-105	373.00
IUUC-Cja-019780	Callithrix jacchus	85.71	0.00e+00	625.00
IUUC-Cfa-021252	Canis familiaris	88.80	2.00e-179	621.00
IUUC-Cpo-022047	Cavia porcellus	84.43	7.00e-180	622.00
IUUC-Csa-023161	Chlorocebus sabaeus	87.33	0.00e+00	660.00
IUUC-Cho-024316	Choloepus hoffmanni	85.81	4.00e-148	516.00
IUUC-Dre-028596	Danio rerio	56.02	3.00e-109	387.00
IUUC-Dno-029333	Dasypus novemcinctus	88.71	0.00e+00	640.00
IUUC-Ete-033163	Echinops telfairi	83.71	9.00e-161	559.00
IUUC-Eca-033994	Equus caballus	89.89	0.00e+00	656.00
IUUC-Eeu-035162	Erinaceus europaeus	81.33	9.00e-122	429.00
IUUC-Fca-036418	Felis catus	88.59	0.00e+00	671.00
IUUC-Fal-037427	Ficedula albicollis	66.48	8.00e-129	453.00
IUUC-Gga-041053	Gallus gallus	67.31	7.00e-127	446.00
IUUC-Ggo-045436	Gorilla gorilla	87.05	0.00e+00	658.00
IUUC-Hsa-045798	Homo sapiens	87.05	0.00e+00	658.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	84.78	8.00e-176	609.00
IUUC-Lch-050639	Latimeria chalumnae	60.61	7.00e-120	423.00
IUUC-Laf-053355	Loxodonta africana	80.22	3.00e-169	587.00
IUUC-Mcc-055222	Macaca mulatta	86.50	0.00e+00	627.00
IUUC-Meu-056692	Macropus eugenii	75.48	4.00e-154	537.00
IUUC-Mga-059298	Meleagris gallopavo	66.94	2.00e-126	445.00
IUUC-Mmr-061792	Microcebus murinus	87.02	1.00e-179	622.00
IUUC-Mdo-062986	Monodelphis domestica	77.53	7.00e-164	570.00
IUUC-Mmu-063356	Mus musculus	83.91	2.00e-178	618.00
IUUC-Mpu-066273	Mustela putorius furo	88.04	0.00e+00	668.00
IUUC-Mlu-066953	Myotis lucifugus	88.80	0.00e+00	659.00
IUUC-Nle-070075	Nomascus leucogenys	86.07	0.00e+00	659.00
IUUC-Opr-070838	Ochotona princeps	85.67	2.00e-179	621.00
IUUC-Ont-071967	Oreochromis niloticus	73.43	8.00e-55	207.00
IUUC-Ocu-074807	Oryctolagus cuniculus	86.34	0.00e+00	648.00
IUUC-Obr-076159	Oryza brachyantha	39.29	1.00e-07	48.90
IUUC-Ola-086903	Oryzias latipes	68.46	2.00e-55	209.00
IUUC-Oga-088536	Otolemur garnettii	85.36	7.00e-173	599.00
IUUC-Oar-089838	Ovis aries	96.49	0.00e+00	687.00
IUUC-Ptr-090962	Pan troglodytes	87.33	0.00e+00	659.00
IUUC-Pan-092853	Papio anubis	86.50	0.00e+00	655.00
IUUC-Psi-093164	Pelodiscus sinensis	68.87	1.00e-121	429.00
IUUC-Pma-094104	Petromyzon marinus	43.63	3.00e-55	209.00
IUUC-Pno-094968	Phaeosphaeria nodorum	38.78	9.00e-09	57.00
IUUC-Pab-098304	Pongo abelii	86.89	0.00e+00	662.00
IUUC-Pca-100316	Procavia capensis	83.47	5.00e-171	593.00
IUUC-Ppe-101490	Prunus persica	36.59	2.00e-08	53.90
IUUC-Pva-102612	Pteropus vampyrus	74.38	8.00e-152	529.00
IUUC-Rno-105449	Rattus norvegicus	85.64	6.00e-176	609.00
IUUC-Sha-107578	Sarcophilus harrisii	76.00	5.00e-151	526.00
IUUC-Sar-113638	Sorex araneus	85.12	2.00e-172	598.00
IUUC-Ssc-116401	Sus scrofa	89.76	0.00e+00	684.00
IUUC-Tru-118765	Takifugu rubripes	50.42	2.00e-82	298.00
IUUC-Tsy-118850	Tarsius syrichta	84.16	5.00e-144	503.00
IUUC-Tbe-128086	Tupaia belangeri	78.51	5.00e-166	576.00
IUUC-Ttr-128249	Tursiops truncatus	73.88	2.00e-142	498.00
IUUC-Vpa-130816	Vicugna pacos	89.53	1.00e-41	162.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence