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Tag Content
UUCD2 ID IUUC-Gga-040359
UUCD1 version UUC-GaG-00126
Ensembl Protein ID ENSGALP00000026967.4
UniProt Accession E1BW48; E1BW48_CHICK
Genbank Protein ID ENSGALP00000026967
Protein Name Uncharacterized protein
Genbank Nucleotide ID AADN04000081
Gene Name HERC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000016739.5 ENSGALT00000027018.5 ENSGALP00000026967.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 3.50e-86 290.0 4469 4798
Active Site
Position(s) Description Evidence
4767 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l np      h+++F+flG+llg+a+++g +l
   Q: 4469 RVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPaakslLHMNMFRFLGVLLGIAIRTGSPL 4555
           4566*********************************************************************************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            l+l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++ +++t +N+ eYv+
   Q: 4556 SLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPNASGQDIQLSSKYTHITLDNRAEYVR 4637
           ***************************************99999999999*999.....788999999******************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           l ++yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er+
   Q: 4638 LAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-IEPTASLIQWFWEVMESFSNTERS 4722
           *********.**************************************************77.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            fL+Fv+g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4723 LFLRFVWGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4798
           *************.8*************999988888***********************************99875 PP
   
Organism Gallus gallus
Protein Sequence
(Fasta)
MSSESFCLAA QARFDSKWLK TDLQLAFTRD GLCGLWNEMV KDGEIVYPGT EFTQNGELPP 60
RKDDSTECQT ASKKEEQNDK EKKDEEEAPP PTYRARSIVE SWVWGKQPDV NELKECLHVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040359|E3,HECT|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCCTCGG AATCTTTCTG TCTGGCTGCT CAGGCCAGGT TTGACTCCAA ATGGCTGAAG 60
ACAGACCTAC AGGTAAGGCG TCAGACTGCT GCGTCGCACC TTTCGGATGT GGACTGGGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040359|E3,HECT|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR004939--APC_su10/DOC_dom
IPR021097--CPH_domain
IPR001199--Cyt_B5-like_heme/steroid-bd
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR014722--Rib_L2_dom2
IPR000433--Znf_ZZ
PROSITE

PS50255--CYTOCHROME_B5_2
PS51284--DOC
PS50237--HECT
PS51416--MIB_HERC2
PS00626--RCC1_2
PS50012--RCC1_3
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00173--Cyt-b5
PF00632--HECT
PF06701--MIB_HERC2
PF00415--RCC1
PF00569--ZZ
PRINTS

PR00633--RCCNDNSATION
SMART

SM01337--APC10
SM01117--Cyt-b5
SM00119--HECTc
SM00291--ZnF_ZZ
Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007283--P:spermatogenesis
KEGG gga:418682
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002112 Ailuropoda melanoleuca 91.37 0.00e+00 6863.00
IUUC-Atr-003065 Amborella trichopoda 35.29 1.00e-51 198.00
IUUC-Apl-003983 Anas platyrhynchos 98.95 0.00e+00 9036.00
IUUC-Aca-004300 Anolis carolinensis 95.10 0.00e+00 8688.00
IUUC-Aly-006441 Arabidopsis lyrata 34.15 4.00e-45 176.00
IUUC-Ame-010621 Astyanax mexicanus 87.83 0.00e+00 7162.00
IUUC-Bta-013067 Bos taurus 90.43 0.00e+00 8253.00
IUUC-Bdi-014093 Brachypodium distachyon 33.76 7.00e-50 192.00
IUUC-Bol-015203 Brassica oleracea 34.27 1.00e-52 201.00
IUUC-Bra-016737 Brassica rapa 34.27 5.00e-48 186.00
IUUC-Cja-019687 Callithrix jacchus 89.77 0.00e+00 8088.00
IUUC-Cfa-020672 Canis familiaris 91.18 0.00e+00 8327.00
IUUC-Cpo-021819 Cavia porcellus 88.37 0.00e+00 8047.00
IUUC-Csa-023817 Chlorocebus sabaeus 91.26 0.00e+00 8305.00
IUUC-Cho-024387 Choloepus hoffmanni 91.84 0.00e+00 1835.00
IUUC-Cin-025709 Ciona intestinalis 54.68 0.00e+00 2230.00
IUUC-Csv-026336 Ciona savignyi 42.55 0.00e+00 3023.00
IUUC-Dre-027717 Danio rerio 84.39 0.00e+00 7489.00
IUUC-Dno-029296 Dasypus novemcinctus 91.34 0.00e+00 8298.00
IUUC-Dor-030979 Dipodomys ordii 85.44 0.00e+00 2761.00
IUUC-Dme-032171 Drosophila melanogaster 60.12 0.00e+00 1529.00
IUUC-Ete-032687 Echinops telfairi 85.79 0.00e+00 2697.00
IUUC-Eca-034046 Equus caballus 90.44 0.00e+00 8264.00
IUUC-Eeu-034859 Erinaceus europaeus 91.74 0.00e+00 1900.00
IUUC-Fca-036262 Felis catus 91.26 0.00e+00 8353.00
IUUC-Fal-037562 Ficedula albicollis 98.37 0.00e+00 8910.00
IUUC-Gmo-039054 Gadus morhua 88.99 0.00e+00 1123.00
IUUC-Gac-041879 Gasterosteus aculeatus 92.53 0.00e+00 1058.00
IUUC-Ggo-044692 Gorilla gorilla 94.44 0.00e+00 4225.00
IUUC-Hsa-045995 Homo sapiens 91.49 0.00e+00 8363.00
IUUC-Hvu-047529 Hordeum vulgare 35.65 8.00e-50 192.00
IUUC-Itr-048553 Ictidomys tridecemlineatus 87.55 0.00e+00 2261.00
IUUC-Lch-049808 Latimeria chalumnae 88.96 0.00e+00 3427.00
IUUC-Lpe-051482 Leersia perrieri 34.46 6.00e-47 182.00
IUUC-Loc-052685 Lepisosteus oculatus 87.75 0.00e+00 7849.00
IUUC-Laf-053372 Loxodonta africana 90.48 0.00e+00 8238.00
IUUC-Mcc-054693 Macaca mulatta 91.30 0.00e+00 8337.00
IUUC-Meu-056660 Macropus eugenii 97.96 0.00e+00 1952.00
IUUC-Mga-059371 Meleagris gallopavo 99.30 0.00e+00 7740.00
IUUC-Mmr-060787 Microcebus murinus 91.61 0.00e+00 8406.00
IUUC-Mdo-062518 Monodelphis domestica 92.55 0.00e+00 8348.00
IUUC-Mmu-063690 Mus musculus 90.08 0.00e+00 8222.00
IUUC-Mpu-066478 Mustela putorius furo 90.67 0.00e+00 8278.00
IUUC-Mlu-067596 Myotis lucifugus 86.65 0.00e+00 4231.00
IUUC-Nle-069445 Nomascus leucogenys 88.57 0.00e+00 2040.00
IUUC-Opr-070990 Ochotona princeps 86.02 0.00e+00 2936.00
IUUC-Ont-072285 Oreochromis niloticus 86.04 0.00e+00 7609.00
IUUC-Oan-072721 Ornithorhynchus anatinus 87.33 0.00e+00 3496.00
IUUC-Ocu-074273 Oryctolagus cuniculus 90.62 0.00e+00 8265.00
IUUC-Oba-075573 Oryza barthii 33.68 8.00e-46 179.00
IUUC-Obr-076107 Oryza brachyantha 33.77 4.00e-50 193.00
IUUC-Ogl-077193 Oryza glaberrima 33.68 8.00e-46 179.00
IUUC-Ogu-078817 Oryza glumaepatula 33.68 7.00e-46 179.00
IUUC-Oin-079609 Oryza indica 32.75 3.00e-49 190.00
IUUC-Olo-080629 Oryza longistaminata 33.68 8.00e-46 179.00
IUUC-Ome-081686 Oryza meridionalis 33.68 3.00e-46 180.00
IUUC-Opu-084137 Oryza punctata 33.94 2.00e-46 181.00
IUUC-Oru-085013 Oryza rufipogon 33.68 7.00e-46 179.00
IUUC-Osa-085597 Oryza sativa 33.68 8.00e-46 179.00
IUUC-Ola-087346 Oryzias latipes 94.12 0.00e+00 1209.00
IUUC-Oga-088742 Otolemur garnettii 90.51 0.00e+00 8201.00
IUUC-Oar-090093 Ovis aries 90.67 0.00e+00 8258.00
IUUC-Ptr-091034 Pan troglodytes 86.80 0.00e+00 5504.00
IUUC-Pan-092783 Papio anubis 89.17 0.00e+00 8113.00
IUUC-Psi-094027 Pelodiscus sinensis 96.44 0.00e+00 8426.00
IUUC-Pfo-096208 Poecilia formosa 83.18 0.00e+00 6225.00
IUUC-Pab-097681 Pongo abelii 86.76 0.00e+00 2429.00
IUUC-Pca-100705 Procavia capensis 92.88 0.00e+00 1142.00
IUUC-Pva-103147 Pteropus vampyrus 81.45 0.00e+00 2377.00
IUUC-Rno-105458 Rattus norvegicus 90.08 0.00e+00 8212.00
IUUC-Sha-106959 Sarcophilus harrisii 84.14 0.00e+00 7220.00
IUUC-Sit-109917 Setaria italica 36.47 9.00e-49 188.00
IUUC-Sly-110961 Solanum lycopersicum 35.33 1.00e-53 204.00
IUUC-Sar-113532 Sorex araneus 82.75 0.00e+00 1790.00
IUUC-Sbi-114352 Sorghum bicolor 32.39 7.00e-50 192.00
IUUC-Ssc-115337 Sus scrofa 85.69 0.00e+00 2808.00
IUUC-Tgu-116789 Taeniopygia guttata 98.35 0.00e+00 8950.00
IUUC-Tru-118129 Takifugu rubripes 85.09 0.00e+00 7651.00
IUUC-Tsy-119302 Tarsius syrichta 80.42 0.00e+00 1219.00
IUUC-Tni-120374 Tetraodon nigroviridis 83.65 0.00e+00 7480.00
IUUC-Tca-121094 Theobroma cacao 35.59 1.00e-54 208.00
IUUC-Tae-124157 Triticum aestivum 33.51 1.00e-49 191.00
IUUC-Tbe-128137 Tupaia belangeri 82.49 0.00e+00 2190.00
IUUC-Ttr-128273 Tursiops truncatus 86.71 0.00e+00 4845.00
IUUC-Vpa-130471 Vicugna pacos 80.67 0.00e+00 1448.00
IUUC-Xtr-132185 Xenopus tropicalis 88.69 0.00e+00 8014.00
IUUC-Xma-133233 Xiphophorus maculatus 85.31 0.00e+00 7581.00
Created Date 25-Jun-2017

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