iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054497

UUCD1 version

UUC-LoA-00449

Ensembl Protein ID

ENSLAFP00000010970.2

UniProt Accession

G3TAQ3; G3TAQ3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

GAN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013109.2	ENSLAFT00000013108.2	ENSLAFP00000010970.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.80e-09	36.1	30	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.20e-08	32.1	133	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik..dvqpevfrallkFlYtgkldene 69
           +D  lv++gee++++k +Laa+S++ +   l+  + ++ +++++i+  +++  v++++l+++ +g+++++e
   Q: 30   CDAHLVLDGEEIPVQKNILAAASPYIRWTKLNYNPPKDDGSTYKIEleGISVMVMKEILDYIFSGQIRLSE 100
           899***********************97665444433335555555527*****************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eNc+gi++fA +y++++++  a +++++hF+
   Q: 133  ENCIGIRDFALHYCLHHVHYLATEYLETHFR 163
           9*****************************7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

PSIAAAIIDP QHAARLLRAL SSFREESRFC DAHLVLDGEE IPVQKNILAA ASPYIRWTKL 60
NYNPPKDDGS TYKIELEGIS VMVMKEILDY IFSGQIRLSE DTIQDVVQAA DLLLLTDLKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTCCATCG CTGCAGCAAT CATTGCGGGN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030579--KLHL16
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0007010--P:cytoskeleton organization
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002164	Ailuropoda melanoleuca	97.25	0.00e+00	1061.00
IUUC-Apl-004132	Anas platyrhynchos	91.68	0.00e+00	1003.00
IUUC-Aca-005264	Anolis carolinensis	90.08	0.00e+00	1080.00
IUUC-Ame-011222	Astyanax mexicanus	68.59	0.00e+00	689.00
IUUC-Bta-012855	Bos taurus	97.14	0.00e+00	1154.00
IUUC-Cja-019865	Callithrix jacchus	97.65	0.00e+00	1159.00
IUUC-Cfa-020864	Canis familiaris	97.48	0.00e+00	1160.00
IUUC-Cpo-021500	Cavia porcellus	96.81	0.00e+00	1148.00
IUUC-Csa-023114	Chlorocebus sabaeus	98.15	0.00e+00	1165.00
IUUC-Cho-024996	Choloepus hoffmanni	97.97	0.00e+00	1058.00
IUUC-Dre-028758	Danio rerio	67.47	6.00e-177	613.00
IUUC-Dno-029380	Dasypus novemcinctus	97.80	0.00e+00	1154.00
IUUC-Dor-030704	Dipodomys ordii	97.67	0.00e+00	768.00
IUUC-Ete-032632	Echinops telfairi	96.47	0.00e+00	1143.00
IUUC-Eca-034092	Equus caballus	97.99	0.00e+00	1066.00
IUUC-Eeu-034482	Erinaceus europaeus	91.96	0.00e+00	1069.00
IUUC-Fca-035706	Felis catus	97.99	0.00e+00	1064.00
IUUC-Fal-037414	Ficedula albicollis	91.65	0.00e+00	952.00
IUUC-Gmo-039716	Gadus morhua	67.74	0.00e+00	849.00
IUUC-Gga-040801	Gallus gallus	91.41	0.00e+00	1095.00
IUUC-Gac-042023	Gasterosteus aculeatus	67.17	0.00e+00	853.00
IUUC-Ggo-045209	Gorilla gorilla	98.35	0.00e+00	1070.00
IUUC-Hsa-046018	Homo sapiens	98.15	0.00e+00	1165.00
IUUC-Itr-048003	Ictidomys tridecemlineatus	98.87	0.00e+00	895.00
IUUC-Lch-050253	Latimeria chalumnae	81.90	0.00e+00	977.00
IUUC-Loc-052224	Lepisosteus oculatus	80.54	0.00e+00	960.00
IUUC-Mcc-055363	Macaca mulatta	98.15	0.00e+00	1165.00
IUUC-Meu-056415	Macropus eugenii	87.23	0.00e+00	1015.00
IUUC-Mga-059506	Meleagris gallopavo	91.68	0.00e+00	1002.00
IUUC-Mmr-060695	Microcebus murinus	97.98	0.00e+00	1165.00
IUUC-Mdo-062539	Monodelphis domestica	94.45	0.00e+00	1127.00
IUUC-Mmu-063833	Mus musculus	96.64	0.00e+00	1152.00
IUUC-Mpu-066163	Mustela putorius furo	97.48	0.00e+00	1157.00
IUUC-Mlu-067351	Myotis lucifugus	97.65	0.00e+00	1161.00
IUUC-Nle-069432	Nomascus leucogenys	97.98	0.00e+00	1164.00
IUUC-Opr-070941	Ochotona princeps	87.80	0.00e+00	921.00
IUUC-Ont-072620	Oreochromis niloticus	69.24	0.00e+00	879.00
IUUC-Oan-073408	Ornithorhynchus anatinus	94.87	5.00e-147	513.00
IUUC-Ocu-074067	Oryctolagus cuniculus	96.97	0.00e+00	1153.00
IUUC-Ola-087263	Oryzias latipes	67.90	0.00e+00	850.00
IUUC-Oga-088387	Otolemur garnettii	97.16	0.00e+00	1157.00
IUUC-Oar-089890	Ovis aries	97.26	0.00e+00	1053.00
IUUC-Ptr-090867	Pan troglodytes	98.89	0.00e+00	1068.00
IUUC-Pan-092790	Papio anubis	98.35	0.00e+00	1070.00
IUUC-Psi-093381	Pelodiscus sinensis	91.84	0.00e+00	917.00
IUUC-Pma-094681	Petromyzon marinus	67.26	6.00e-157	547.00
IUUC-Pfo-096446	Poecilia formosa	67.96	0.00e+00	865.00
IUUC-Pab-097839	Pongo abelii	98.15	0.00e+00	1166.00
IUUC-Pca-101042	Procavia capensis	79.86	2.00e-116	412.00
IUUC-Pva-102911	Pteropus vampyrus	97.82	0.00e+00	1160.00
IUUC-Rno-105073	Rattus norvegicus	95.17	0.00e+00	1143.00
IUUC-Sha-107321	Sarcophilus harrisii	93.45	0.00e+00	1145.00
IUUC-Sar-113417	Sorex araneus	87.80	0.00e+00	920.00
IUUC-Ssc-115450	Sus scrofa	97.31	0.00e+00	1159.00
IUUC-Tgu-117089	Taeniopygia guttata	90.42	0.00e+00	1076.00
IUUC-Tru-118452	Takifugu rubripes	64.53	0.00e+00	810.00
IUUC-Tsy-119125	Tarsius syrichta	93.39	0.00e+00	889.00
IUUC-Tni-120845	Tetraodon nigroviridis	64.42	0.00e+00	806.00
IUUC-Tbe-127688	Tupaia belangeri	69.50	7.00e-114	403.00
IUUC-Ttr-128621	Tursiops truncatus	97.83	0.00e+00	913.00
IUUC-Vpa-130159	Vicugna pacos	99.03	2.00e-180	625.00
IUUC-Xtr-132635	Xenopus tropicalis	84.38	0.00e+00	994.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence