iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118279

Ensembl Protein ID

ENSTRUP00000033416.1

UniProt Accession

H2U900; H2U900_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013136.1	ENSTRUT00000033542.1	ENSTRUP00000033416.1
ENSTRUG00000013136.1	ENSTRUT00000033543.1	ENSTRUP00000033417.1
ENSTRUG00000013136.1	ENSTRUT00000033544.1	ENSTRUP00000033418.1
ENSTRUG00000013136.1	ENSTRUT00000033545.1	ENSTRUP00000033419.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.60e-46	155.1	252	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +ly++ a + +eL +  Gd ++vi   + + gWl+g  e +g+rG+fP+ Fv+
   Q: 252  YVVALYEFRAMEAGELDFDMGDRIRVI--STLEDGWLEG--EVQGRRGIFPHRFVK 303
           689************************..89999*****..9************98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MEAGSVVRTV FEFLPSVSEE LPLFTGDVIE VLSVIDEFWL LGNKDGVTGQ FPSTFVEEVT 60
IPSTKPGDRL YVCINDFNAA DTGSLSLKRG DVVVGETGGS LDLGETWQRG CNAWGMRGHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGCAG GTTCGGTGGT GCGCACCGTA TTCGAGTTTC TGCCCAGCGT CTCTGAGGAG 60
CTGCCCCTCT TCACCGGTGA TGTCATCGAG GTGCTCAGTG TCATTGATGA GTTCTGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0060271--P:cilium assembly
GO:0001822--P:kidney development
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	55.57	0.00e+00	905.00
IUUC-Apl-003934	Anas platyrhynchos	63.33	0.00e+00	831.00
IUUC-Aca-005005	Anolis carolinensis	56.91	2.00e-92	334.00
IUUC-Ame-011361	Astyanax mexicanus	68.59	0.00e+00	1145.00
IUUC-Bta-013210	Bos taurus	56.58	0.00e+00	890.00
IUUC-Cel-018396	Caenorhabditis elegans	26.01	1.00e-35	145.00
IUUC-Cja-019104	Callithrix jacchus	54.36	0.00e+00	879.00
IUUC-Cfa-020960	Canis familiaris	56.01	0.00e+00	915.00
IUUC-Cpo-022440	Cavia porcellus	55.83	0.00e+00	922.00
IUUC-Csa-023391	Chlorocebus sabaeus	56.01	0.00e+00	938.00
IUUC-Cho-024795	Choloepus hoffmanni	46.62	0.00e+00	690.00
IUUC-Cin-025137	Ciona intestinalis	34.80	2.00e-30	125.00
IUUC-Dre-027932	Danio rerio	66.70	0.00e+00	1107.00
IUUC-Dno-029750	Dasypus novemcinctus	54.36	0.00e+00	926.00
IUUC-Dor-031109	Dipodomys ordii	59.95	0.00e+00	823.00
IUUC-Ete-032660	Echinops telfairi	57.16	0.00e+00	680.00
IUUC-Eca-033433	Equus caballus	55.82	0.00e+00	905.00
IUUC-Eeu-034929	Erinaceus europaeus	55.40	2.00e-115	410.00
IUUC-Fca-035859	Felis catus	55.41	0.00e+00	926.00
IUUC-Fal-036653	Ficedula albicollis	57.44	0.00e+00	907.00
IUUC-Gmo-038948	Gadus morhua	73.88	0.00e+00	995.00
IUUC-Gga-040279	Gallus gallus	54.65	0.00e+00	894.00
IUUC-Gac-041641	Gasterosteus aculeatus	72.45	0.00e+00	1264.00
IUUC-Ggo-044900	Gorilla gorilla	30.36	2.00e-76	280.00
IUUC-Hsa-046063	Homo sapiens	56.00	0.00e+00	927.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	54.83	0.00e+00	917.00
IUUC-Lch-049865	Latimeria chalumnae	56.50	0.00e+00	718.00
IUUC-Loc-051754	Lepisosteus oculatus	65.91	0.00e+00	1181.00
IUUC-Lma-052966	Leptosphaeria maculans	48.21	1.00e-09	58.20
IUUC-Laf-054037	Loxodonta africana	54.41	0.00e+00	946.00
IUUC-Mcc-055002	Macaca mulatta	55.91	0.00e+00	937.00
IUUC-Meu-056420	Macropus eugenii	55.18	0.00e+00	638.00
IUUC-Mor-057139	Magnaporthe oryzae	23.96	2.00e-10	61.60
IUUC-Mga-059868	Meleagris gallopavo	56.12	0.00e+00	877.00
IUUC-Mmr-060767	Microcebus murinus	56.24	0.00e+00	933.00
IUUC-Mdo-061939	Monodelphis domestica	54.73	0.00e+00	879.00
IUUC-Mmu-063980	Mus musculus	53.76	0.00e+00	897.00
IUUC-Mpu-065913	Mustela putorius furo	56.56	0.00e+00	959.00
IUUC-Mlu-067340	Myotis lucifugus	55.08	0.00e+00	900.00
IUUC-Nle-069343	Nomascus leucogenys	56.00	0.00e+00	928.00
IUUC-Opr-070694	Ochotona princeps	54.16	0.00e+00	916.00
IUUC-Ont-071844	Oreochromis niloticus	70.39	0.00e+00	1210.00
IUUC-Oan-073605	Ornithorhynchus anatinus	63.64	1.00e-19	91.30
IUUC-Ocu-074406	Oryctolagus cuniculus	55.53	0.00e+00	944.00
IUUC-Ola-087343	Oryzias latipes	70.46	0.00e+00	836.00
IUUC-Oga-088847	Otolemur garnettii	56.11	0.00e+00	924.00
IUUC-Oar-089817	Ovis aries	55.34	0.00e+00	880.00
IUUC-Ptr-090508	Pan troglodytes	30.03	1.00e-75	277.00
IUUC-Pan-092104	Papio anubis	55.91	0.00e+00	934.00
IUUC-Psi-094045	Pelodiscus sinensis	53.79	9.00e-79	288.00
IUUC-Pma-094663	Petromyzon marinus	42.09	3.00e-166	580.00
IUUC-Pfo-096714	Poecilia formosa	69.81	0.00e+00	1236.00
IUUC-Pab-097918	Pongo abelii	56.40	0.00e+00	929.00
IUUC-Pca-101096	Procavia capensis	51.01	8.00e-123	435.00
IUUC-Pva-102490	Pteropus vampyrus	54.40	0.00e+00	933.00
IUUC-Rno-105908	Rattus norvegicus	54.86	0.00e+00	873.00
IUUC-Sha-107509	Sarcophilus harrisii	56.20	0.00e+00	917.00
IUUC-Ssc-115250	Sus scrofa	56.16	0.00e+00	884.00
IUUC-Tni-120459	Tetraodon nigroviridis	88.43	0.00e+00	1046.00
IUUC-Tbe-127753	Tupaia belangeri	51.27	2.00e-81	298.00
IUUC-Ttr-129096	Tursiops truncatus	54.23	0.00e+00	893.00
IUUC-Vpa-130643	Vicugna pacos	56.65	0.00e+00	684.00
IUUC-Xtr-131979	Xenopus tropicalis	57.17	0.00e+00	1001.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence