iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066422

Ensembl Protein ID

ENSMPUP00000000480.1

UniProt Accession

M3XN30; M3XN30_MUSPF

Genbank Protein ID

ENSMPUP00000000480

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01014669

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000486.1	ENSMPUT00000000491.1	ENSMPUP00000000480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.90e-25	87.4	403	474
E3 adaptor/Cullin RING/DCX/DWD	2.30e-41	138.0	11	43
UBD/Beta-Prp	1.20e-54	185.5	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 403  IPDEFLCPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLPSVVLTPNRTLKMAISRWLETHQ 474
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l++++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFT 43
           9*********548***************98876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  ++sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g +l+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SSSLLATCSLDKTIRLYSLSDFTElpHSPLKFHTYAVHCCCFSPSGHVLASCSTDGTTVLWNTQNGETLAVM 92
           566666655.55899..9********************666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w+ ++++ ++ + s++dg+    +++p+gnl+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPTgSPVRVCQFSPDSTCLVSGAADGTVVLWNAQSYKLYR-CGSVKDGSLVACAFSPNGNLFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           *765267*********************************9.**********************************8.6678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d ++k+w ++
   Q: 179  HDLGITCCDFSSQPvtdgehglqfFRLASCGQDCQIKIWVVS 220
           ************99*************************876 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTELPHSPL KFHTYAVHCC 60
CFSPSGHVLA SCSTDGTTVL WNTQNGETLA VMEQPTGSPV RVCQFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCTGGCG CGAGGCGTGT TCGTGGGGCG GGGCCTGTTT TCTTTCTTGC AGGGTTTCCG 60
CGGTTGCCAG CCCCGCCCGC CTCACCTGCG CGTCACGTGA TCCTCGCGCG CCTGGGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	96.64	0.00e+00	954.00
IUUC-Apl-003529	Anas platyrhynchos	75.63	0.00e+00	768.00
IUUC-Aca-004257	Anolis carolinensis	71.05	0.00e+00	704.00
IUUC-Ame-011357	Astyanax mexicanus	52.83	3.00e-116	412.00
IUUC-Bta-013032	Bos taurus	88.47	0.00e+00	877.00
IUUC-Cja-018743	Callithrix jacchus	91.39	0.00e+00	911.00
IUUC-Cfa-021197	Canis familiaris	94.54	0.00e+00	940.00
IUUC-Cpo-022279	Cavia porcellus	89.50	0.00e+00	892.00
IUUC-Csa-023954	Chlorocebus sabaeus	92.02	0.00e+00	916.00
IUUC-Cho-025083	Choloepus hoffmanni	73.02	2.00e-155	541.00
IUUC-Cin-025786	Ciona intestinalis	34.54	7.00e-79	287.00
IUUC-Dre-028087	Danio rerio	57.00	3.00e-145	508.00
IUUC-Dno-028919	Dasypus novemcinctus	91.39	0.00e+00	913.00
IUUC-Dor-031112	Dipodomys ordii	88.66	0.00e+00	877.00
IUUC-Ete-032405	Echinops telfairi	86.88	0.00e+00	628.00
IUUC-Eca-033254	Equus caballus	90.13	0.00e+00	892.00
IUUC-Eeu-034545	Erinaceus europaeus	85.50	0.00e+00	827.00
IUUC-Fca-035482	Felis catus	94.75	0.00e+00	939.00
IUUC-Fal-036976	Ficedula albicollis	61.52	2.00e-164	572.00
IUUC-Gmo-039213	Gadus morhua	55.46	2.00e-138	485.00
IUUC-Gga-040561	Gallus gallus	74.42	0.00e+00	754.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.98	2.00e-141	495.00
IUUC-Ggo-045503	Gorilla gorilla	92.02	0.00e+00	919.00
IUUC-Hsa-045910	Homo sapiens	92.02	0.00e+00	919.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	89.92	0.00e+00	706.00
IUUC-Loc-052307	Lepisosteus oculatus	59.72	3.00e-168	584.00
IUUC-Laf-053587	Loxodonta africana	90.55	0.00e+00	904.00
IUUC-Mcc-055679	Macaca mulatta	92.23	0.00e+00	920.00
IUUC-Meu-055962	Macropus eugenii	71.64	0.00e+00	656.00
IUUC-Mga-059652	Meleagris gallopavo	74.00	0.00e+00	756.00
IUUC-Mmr-060943	Microcebus murinus	89.52	0.00e+00	896.00
IUUC-Mdo-062592	Monodelphis domestica	81.84	0.00e+00	823.00
IUUC-Mmu-063577	Mus musculus	82.56	0.00e+00	818.00
IUUC-Mlu-067250	Myotis lucifugus	89.71	0.00e+00	889.00
IUUC-Nle-069517	Nomascus leucogenys	91.81	0.00e+00	917.00
IUUC-Opr-070776	Ochotona princeps	89.29	0.00e+00	879.00
IUUC-Ont-071821	Oreochromis niloticus	57.74	6.00e-151	527.00
IUUC-Oan-073706	Ornithorhynchus anatinus	82.11	0.00e+00	825.00
IUUC-Ocu-074766	Oryctolagus cuniculus	81.21	0.00e+00	793.00
IUUC-Ola-086531	Oryzias latipes	56.81	5.00e-147	514.00
IUUC-Oga-088388	Otolemur garnettii	88.24	0.00e+00	882.00
IUUC-Oar-089748	Ovis aries	88.24	0.00e+00	875.00
IUUC-Ptr-090616	Pan troglodytes	91.75	0.00e+00	911.00
IUUC-Pan-091769	Papio anubis	91.28	0.00e+00	655.00
IUUC-Psi-093334	Pelodiscus sinensis	79.41	0.00e+00	743.00
IUUC-Pma-094383	Petromyzon marinus	48.83	1.00e-134	473.00
IUUC-Pfo-096801	Poecilia formosa	56.16	7.00e-148	516.00
IUUC-Pab-098139	Pongo abelii	90.72	0.00e+00	736.00
IUUC-Pca-100523	Procavia capensis	85.80	3.00e-165	574.00
IUUC-Pva-102286	Pteropus vampyrus	90.13	0.00e+00	869.00
IUUC-Rno-104831	Rattus norvegicus	84.66	0.00e+00	840.00
IUUC-Sha-107499	Sarcophilus harrisii	83.61	0.00e+00	840.00
IUUC-Sar-113389	Sorex araneus	85.71	0.00e+00	830.00
IUUC-Tgu-116769	Taeniopygia guttata	73.74	0.00e+00	736.00
IUUC-Tru-118774	Takifugu rubripes	53.50	9.00e-140	489.00
IUUC-Tsy-119595	Tarsius syrichta	78.88	0.00e+00	635.00
IUUC-Tni-119850	Tetraodon nigroviridis	57.68	1.00e-148	519.00
IUUC-Tbe-127938	Tupaia belangeri	80.98	1.00e-143	502.00
IUUC-Ttr-128193	Tursiops truncatus	90.33	0.00e+00	763.00
IUUC-Vpa-130275	Vicugna pacos	92.44	0.00e+00	915.00
IUUC-Xtr-131982	Xenopus tropicalis	61.26	4.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence