iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000002618.7	ENSRNOT00000003558.7	ENSRNOP00000003558.6
ENSRNOG00000002618.7	ENSRNOT00000087997.1	ENSRNOP00000072879.1
ENSRNOG00000002618.7	ENSRNOT00000083301.1	ENSRNOP00000071484.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.90e-12	47.2	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv l+v g e  ah++vLa +S+++   f+++ +     + v+++d+ pe++++ll++ Yt +l+
   Q: 32   CDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHG-VSHVKLDDLNPEAVEVLLNYAYTAQLK 96
           8**********************************777.9************************97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI 60
FNSDSDPHGV SHVKLDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGGGAGT GCGGCGCGAG CGCGCGCGGC AGCGGCAGTG TGTTCGGGAC GCGCGTGGAG 60
GTCGGTCGCT CGGAGGTGCT GGGCGCGTCG CGGTGGCGGG CGAGTTCCTG CGAGTACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029849--NS1BP
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:2001243--P:negative regulation of intrinsic apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001227	Ailuropoda melanoleuca	98.13	0.00e+00	1323.00
IUUC-Apl-003244	Anas platyrhynchos	90.37	0.00e+00	1219.00
IUUC-Aca-005134	Anolis carolinensis	90.19	0.00e+00	1205.00
IUUC-Ame-011309	Astyanax mexicanus	76.64	0.00e+00	1044.00
IUUC-Bta-013020	Bos taurus	97.51	0.00e+00	1297.00
IUUC-Cel-018672	Caenorhabditis elegans	28.22	1.00e-81	297.00
IUUC-Cja-018717	Callithrix jacchus	96.26	0.00e+00	1266.00
IUUC-Cfa-021209	Canis familiaris	97.98	0.00e+00	1301.00
IUUC-Cpo-022465	Cavia porcellus	96.88	0.00e+00	1312.00
IUUC-Csa-023264	Chlorocebus sabaeus	97.51	0.00e+00	1282.00
IUUC-Cho-024407	Choloepus hoffmanni	96.42	0.00e+00	1113.00
IUUC-Dre-027945	Danio rerio	77.10	0.00e+00	1057.00
IUUC-Dno-028942	Dasypus novemcinctus	92.52	0.00e+00	1235.00
IUUC-Ete-032283	Echinops telfairi	96.57	0.00e+00	1301.00
IUUC-Eca-033877	Equus caballus	97.00	0.00e+00	1017.00
IUUC-Eeu-034923	Erinaceus europaeus	88.79	0.00e+00	1160.00
IUUC-Fca-036378	Felis catus	97.51	0.00e+00	1317.00
IUUC-Fal-037161	Ficedula albicollis	87.63	0.00e+00	1003.00
IUUC-Gmo-039396	Gadus morhua	70.08	0.00e+00	879.00
IUUC-Gga-040338	Gallus gallus	93.64	2.00e-122	430.00
IUUC-Gac-042553	Gasterosteus aculeatus	75.12	0.00e+00	966.00
IUUC-Ggo-045612	Gorilla gorilla	97.35	0.00e+00	1280.00
IUUC-Hsa-045753	Homo sapiens	97.51	0.00e+00	1282.00
IUUC-Itr-048475	Ictidomys tridecemlineatus	98.44	0.00e+00	1327.00
IUUC-Lch-050220	Latimeria chalumnae	78.40	0.00e+00	1024.00
IUUC-Loc-051950	Lepisosteus oculatus	80.00	0.00e+00	1086.00
IUUC-Laf-053878	Loxodonta africana	97.04	0.00e+00	1291.00
IUUC-Mcc-055598	Macaca mulatta	97.51	0.00e+00	1282.00
IUUC-Meu-056133	Macropus eugenii	98.40	1.00e-144	506.00
IUUC-Mga-059538	Meleagris gallopavo	89.44	0.00e+00	1186.00
IUUC-Mmr-061279	Microcebus murinus	97.66	0.00e+00	1289.00
IUUC-Mdo-062952	Monodelphis domestica	95.33	0.00e+00	1293.00
IUUC-Mmu-063566	Mus musculus	99.22	0.00e+00	1305.00
IUUC-Mpu-065828	Mustela putorius furo	97.98	0.00e+00	1321.00
IUUC-Mlu-067313	Myotis lucifugus	96.58	0.00e+00	1266.00
IUUC-Nle-069890	Nomascus leucogenys	97.66	0.00e+00	1285.00
IUUC-Ont-072649	Oreochromis niloticus	76.65	0.00e+00	1000.00
IUUC-Oan-073447	Ornithorhynchus anatinus	93.94	0.00e+00	1240.00
IUUC-Ocu-074680	Oryctolagus cuniculus	90.91	0.00e+00	1180.00
IUUC-Obr-076181	Oryza brachyantha	32.17	6.00e-35	143.00
IUUC-Ogu-078293	Oryza glumaepatula	29.73	5.00e-13	68.60
IUUC-Ome-081176	Oryza meridionalis	29.09	4.00e-07	49.30
IUUC-Ola-086588	Oryzias latipes	75.59	0.00e+00	997.00
IUUC-Oga-088982	Otolemur garnettii	97.82	0.00e+00	1322.00
IUUC-Oar-090409	Ovis aries	97.66	0.00e+00	1299.00
IUUC-Ptr-091365	Pan troglodytes	97.20	0.00e+00	1280.00
IUUC-Pan-092753	Papio anubis	97.51	0.00e+00	1282.00
IUUC-Pma-094393	Petromyzon marinus	71.49	1.00e-88	318.00
IUUC-Pfo-096772	Poecilia formosa	76.36	0.00e+00	1008.00
IUUC-Pab-098516	Pongo abelii	97.66	0.00e+00	1285.00
IUUC-Pca-100604	Procavia capensis	87.94	0.00e+00	1142.00
IUUC-Pva-102388	Pteropus vampyrus	97.04	0.00e+00	1279.00
IUUC-Sha-107436	Sarcophilus harrisii	94.57	0.00e+00	1273.00
IUUC-Tgu-116590	Taeniopygia guttata	85.67	0.00e+00	1139.00
IUUC-Tru-117699	Takifugu rubripes	76.80	0.00e+00	1043.00
IUUC-Tsy-119465	Tarsius syrichta	96.26	0.00e+00	1269.00
IUUC-Tni-120314	Tetraodon nigroviridis	76.02	0.00e+00	1028.00
IUUC-Tbe-127336	Tupaia belangeri	95.33	0.00e+00	1224.00
IUUC-Ttr-128624	Tursiops truncatus	90.34	0.00e+00	1141.00
IUUC-Vpa-130453	Vicugna pacos	97.82	0.00e+00	1254.00
IUUC-Xtr-132900	Xenopus tropicalis	77.93	0.00e+00	1051.00
IUUC-Xma-133881	Xiphophorus maculatus	75.58	0.00e+00	999.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence