iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010967

Ensembl Protein ID

ENSAMXP00000025575.1

UniProt Accession

W5LRN2; W5LRN2_ASTMX

Genbank Protein ID

ENSAMXP00000025575

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01079107

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000024869.1	ENSAMXT00000025595.1	ENSAMXP00000025575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.10e-13	50.7	28	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgklden 68
           +Dvi+vv++  f+ahk +LaasS ++++l  +        + ++++ + v+p+vfr++l+++Ytg+l+e 
   Q: 28   CDVIIVVQNALFRAHKNILAASSLYLKSLVVH-------DNLINLDhEmVSPGVFRVILDYIYTGRLSEG 90
           9*****************************66.......5789999549******************985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MLDAMEVPSH ARHLLLQLNT QRTKGFLCDV IIVVQNALFR AHKNILAASS LYLKSLVVHD 60
NLINLDHEMV SPGVFRVILD YIYTGRLSEG DPTSPTEPNI GAVLAAASYL QLLDLVALCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGATG CCATGGAAGT CCCAAGTCAT GCTAGGCACC TCCTCTTGCA ACTGAACACA 60
CAGCGCACCA AGGGCTTCTT ATGCGACGTA ATTATAGTGG TGCAGAATGC TTTGTTCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR028424--HIC1
IPR000877--Prot_inh_BBI
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005622--C:intracellular
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	62.08	9.00e-91	327.00
IUUC-Aca-004680	Anolis carolinensis	81.06	3.00e-64	239.00
IUUC-Bta-013567	Bos taurus	57.51	6.00e-89	322.00
IUUC-Cja-019621	Callithrix jacchus	82.22	1.00e-38	151.00
IUUC-Cfa-020731	Canis familiaris	59.77	2.00e-94	339.00
IUUC-Cpo-021326	Cavia porcellus	57.79	4.00e-95	342.00
IUUC-Csa-023645	Chlorocebus sabaeus	59.49	5.00e-94	338.00
IUUC-Dre-028027	Danio rerio	75.20	0.00e+00	884.00
IUUC-Dno-028900	Dasypus novemcinctus	57.22	5.00e-93	335.00
IUUC-Fal-036980	Ficedula albicollis	56.58	5.00e-113	401.00
IUUC-Gga-040708	Gallus gallus	64.44	4.00e-110	392.00
IUUC-Gac-041742	Gasterosteus aculeatus	67.96	0.00e+00	719.00
IUUC-Ggo-044591	Gorilla gorilla	57.51	7.00e-90	324.00
IUUC-Hsa-046769	Homo sapiens	57.51	1.00e-89	324.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	59.49	7.00e-94	338.00
IUUC-Lch-049412	Latimeria chalumnae	55.54	0.00e+00	679.00
IUUC-Loc-051883	Lepisosteus oculatus	77.67	1.00e-134	473.00
IUUC-Laf-053358	Loxodonta africana	59.77	2.00e-94	340.00
IUUC-Mcc-054981	Macaca mulatta	59.49	6.00e-94	338.00
IUUC-Meu-056181	Macropus eugenii	56.85	4.00e-56	212.00
IUUC-Mga-059592	Meleagris gallopavo	67.24	3.00e-109	388.00
IUUC-Mmr-061560	Microcebus murinus	57.51	1.00e-92	334.00
IUUC-Mmu-064258	Mus musculus	59.13	4.00e-95	342.00
IUUC-Mpu-065911	Mustela putorius furo	59.77	3.00e-94	339.00
IUUC-Mlu-067575	Myotis lucifugus	60.20	8.00e-85	307.00
IUUC-Ont-072493	Oreochromis niloticus	69.80	0.00e+00	848.00
IUUC-Ola-086584	Oryzias latipes	76.04	2.00e-127	449.00
IUUC-Oga-088774	Otolemur garnettii	58.33	8.00e-92	331.00
IUUC-Ptr-090491	Pan troglodytes	67.36	5.00e-82	298.00
IUUC-Pma-094179	Petromyzon marinus	73.08	2.00e-32	129.00
IUUC-Pfo-096282	Poecilia formosa	70.35	0.00e+00	868.00
IUUC-Pab-098488	Pongo abelii	57.51	8.00e-90	324.00
IUUC-Pca-100667	Procavia capensis	56.20	7.00e-93	335.00
IUUC-Pva-102421	Pteropus vampyrus	59.49	5.00e-98	352.00
IUUC-Rno-105528	Rattus norvegicus	67.98	1.00e-76	281.00
IUUC-Sar-113478	Sorex araneus	66.95	2.00e-81	296.00
IUUC-Ssc-115420	Sus scrofa	58.59	2.00e-97	350.00
IUUC-Tgu-116642	Taeniopygia guttata	65.58	6.00e-111	394.00
IUUC-Tru-118583	Takifugu rubripes	68.62	0.00e+00	806.00
IUUC-Xtr-132210	Xenopus tropicalis	54.41	0.00e+00	655.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence