iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020731

Ensembl Protein ID

ENSCAFP00000028411.4

UniProt Accession

E2QZ59; E2QZ59_CANLF

Genbank Protein ID

ENSCAFP00000028411

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006702

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019257.4	ENSCAFT00000030574.4	ENSCAFP00000028411.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.40e-12	48.1	47	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 47   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 106
           9*****************************77.......4566677678****************98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MTFPEADIFL KSGECAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA 60
HKNVLAASSA YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLADGA EAAAAAAVAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTTTC CTGAAGCGGA CATTTTCCTC AAATCCGGTA ACTGTCTCCG AAGGGGTCAC 60
TTCCCCCAAA CAGTGTTCTC TTCGGAAGTC CCCAGACCCC AGCCTGTGTG CCCGGTGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	93.10	2.00e-153	536.00
IUUC-Aca-004680	Anolis carolinensis	92.86	4.00e-63	236.00
IUUC-Ame-010967	Astyanax mexicanus	61.47	1.00e-94	340.00
IUUC-Bta-013567	Bos taurus	97.86	7.00e-164	570.00
IUUC-Cja-019621	Callithrix jacchus	98.94	8.00e-47	178.00
IUUC-Cpo-021326	Cavia porcellus	93.48	0.00e+00	882.00
IUUC-Csa-023645	Chlorocebus sabaeus	95.63	0.00e+00	892.00
IUUC-Dre-028027	Danio rerio	58.09	3.00e-91	329.00
IUUC-Dno-028900	Dasypus novemcinctus	93.76	0.00e+00	863.00
IUUC-Fal-036980	Ficedula albicollis	62.56	2.00e-111	396.00
IUUC-Gga-040708	Gallus gallus	59.51	0.00e+00	632.00
IUUC-Ggo-044591	Gorilla gorilla	99.70	1.00e-139	490.00
IUUC-Hsa-046769	Homo sapiens	95.91	0.00e+00	878.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	94.06	0.00e+00	884.00
IUUC-Lch-049412	Latimeria chalumnae	55.50	0.00e+00	633.00
IUUC-Loc-051883	Lepisosteus oculatus	58.46	3.00e-89	322.00
IUUC-Laf-053358	Loxodonta africana	90.27	4.00e-166	578.00
IUUC-Mcc-054981	Macaca mulatta	95.66	0.00e+00	853.00
IUUC-Meu-056181	Macropus eugenii	71.10	2.00e-109	389.00
IUUC-Mga-059592	Meleagris gallopavo	73.20	2.00e-103	369.00
IUUC-Mmr-061560	Microcebus murinus	93.84	0.00e+00	843.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	1.00e-90	327.00
IUUC-Mmu-064258	Mus musculus	94.73	0.00e+00	857.00
IUUC-Mpu-065911	Mustela putorius furo	98.60	0.00e+00	909.00
IUUC-Mlu-067575	Myotis lucifugus	77.35	2.00e-124	439.00
IUUC-Ont-072493	Oreochromis niloticus	65.97	3.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	62.42	4.00e-90	325.00
IUUC-Oga-088774	Otolemur garnettii	95.77	0.00e+00	961.00
IUUC-Ptr-090491	Pan troglodytes	96.27	1.00e-125	443.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.91	6.00e-88	318.00
IUUC-Pab-098488	Pongo abelii	93.78	3.00e-173	602.00
IUUC-Pca-100667	Procavia capensis	94.92	1.00e-141	496.00
IUUC-Pva-102421	Pteropus vampyrus	95.50	0.00e+00	884.00
IUUC-Rno-105528	Rattus norvegicus	90.00	0.00e+00	840.00
IUUC-Sar-113478	Sorex araneus	99.17	1.00e-119	424.00
IUUC-Ssc-115420	Sus scrofa	94.27	0.00e+00	866.00
IUUC-Tgu-116642	Taeniopygia guttata	59.12	0.00e+00	626.00
IUUC-Tru-118583	Takifugu rubripes	62.34	1.00e-84	307.00
IUUC-Xtr-132210	Xenopus tropicalis	59.50	0.00e+00	656.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence