iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067575

Ensembl Protein ID

ENSMLUP00000009591.2

UniProt Accession

G1PG49; G1PG49_MYOLU

Genbank Protein ID

ENSMLUP00000009591

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02038100

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000010527.2	ENSMLUT00000010521.2	ENSMLUP00000009591.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-12	48.0	47	105

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  ++   ++       +d v+p vfr +l+F+Ytg+l
   Q: 47   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLND-------HDmVSPAVFRLVLDFIYTGRL 105
           9*****************************88777555.......5679***************98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MTFPEADIFL KSGDCAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA 60
HKNVLAASSA YLKSLVVHDN LLNDHDMVSP AVFRLVLDFI YTGRLADGAE AAASAAVAPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTTTC CTGAAGCGGA CATTTTCCTC AAATCGGGTA ATTGTCTCTG AAAGGGTCAC 60
TTCATCCAAA CAGTTTTCCT CTTCGAAGCC CCCAGGACCC AGCTTGTGTA GCCGGTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	73.71	5.00e-115	408.00
IUUC-Aca-004680	Anolis carolinensis	63.18	3.00e-71	263.00
IUUC-Ame-010967	Astyanax mexicanus	63.84	2.00e-84	306.00
IUUC-Bta-013567	Bos taurus	80.62	0.00e+00	654.00
IUUC-Cja-019621	Callithrix jacchus	96.81	3.00e-44	170.00
IUUC-Cfa-020731	Canis familiaris	81.16	9.00e-138	484.00
IUUC-Cpo-021326	Cavia porcellus	76.95	3.00e-136	479.00
IUUC-Csa-023645	Chlorocebus sabaeus	81.16	3.00e-136	478.00
IUUC-Dre-028027	Danio rerio	60.63	2.00e-84	306.00
IUUC-Dno-028900	Dasypus novemcinctus	78.56	8.00e-126	444.00
IUUC-Fal-036980	Ficedula albicollis	59.28	2.00e-90	327.00
IUUC-Gga-040708	Gallus gallus	68.40	8.00e-84	304.00
IUUC-Ggo-044591	Gorilla gorilla	77.22	6.00e-105	374.00
IUUC-Hsa-046769	Homo sapiens	81.36	1.00e-132	467.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	80.28	9.00e-142	497.00
IUUC-Loc-051883	Lepisosteus oculatus	64.52	4.00e-85	309.00
IUUC-Laf-053358	Loxodonta africana	75.44	0.00e+00	660.00
IUUC-Mcc-054981	Macaca mulatta	81.16	6.00e-136	478.00
IUUC-Meu-056181	Macropus eugenii	88.68	1.00e-62	233.00
IUUC-Mga-059592	Meleagris gallopavo	70.00	1.00e-86	313.00
IUUC-Mmr-061560	Microcebus murinus	79.16	3.00e-126	446.00
IUUC-Mdo-062511	Monodelphis domestica	80.31	5.00e-84	305.00
IUUC-Mmu-064258	Mus musculus	79.36	3.00e-129	456.00
IUUC-Mpu-065911	Mustela putorius furo	81.16	2.00e-136	479.00
IUUC-Ola-086584	Oryzias latipes	64.84	3.00e-82	299.00
IUUC-Oga-088774	Otolemur garnettii	79.76	2.00e-147	516.00
IUUC-Ptr-090491	Pan troglodytes	66.81	5.00e-78	284.00
IUUC-Pfo-096282	Poecilia formosa	62.18	6.00e-81	295.00
IUUC-Pab-098488	Pongo abelii	82.19	0.00e+00	712.00
IUUC-Pca-100667	Procavia capensis	75.14	3.00e-104	372.00
IUUC-Pva-102421	Pteropus vampyrus	80.76	5.00e-124	438.00
IUUC-Rno-105528	Rattus norvegicus	79.32	4.00e-124	438.00
IUUC-Sar-113478	Sorex araneus	66.39	2.00e-77	283.00
IUUC-Ssc-115420	Sus scrofa	75.80	9.00e-123	434.00
IUUC-Tgu-116642	Taeniopygia guttata	70.80	2.00e-85	310.00
IUUC-Tru-118583	Takifugu rubripes	64.06	9.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence