iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020145

Ensembl Protein ID

ENSCAFP00000014580.3

UniProt Accession

E2RBJ3; E2RBJ3_CANLF

Genbank Protein ID

ENSCAFP00000014580

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017565

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009903.3	ENSCAFT00000015751.3	ENSCAFP00000014580.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.79	0.00e+00	736.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDGLAPYRLK LRVKFFVEPH LILQEQTRHI FFLHIKETLL AGHLQCSPEQ AVELCALLAQ 60
TKFGDYNQNT AKYSYEELCA KELSSTTLNS IVAKHKELEG TSQASAEYQV LQIVSAMENY 120

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Nucleotide Sequence
(Fasta)

TCCCCGCAAT TTCCCGGAAG AAGGCGGCCC GGCACACCTG CCGCAGGTGT GTGCATGATG 60
CCGCCTGTCG GGTCCCCCGC GGGGTCTGGC GGTGCCACCT GAGCCCCCAG ATGAGGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019749--Band_41_domain
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF09380--FERM_C
PF00373--FERM_M

PRINTS

PR00935--BAND41

SMART

SM01196--FERM_C

Gene Ontology

GO:0005622--C:intracellular
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	98.16	0.00e+00	778.00
IUUC-Apl-003704	Anas platyrhynchos	90.84	0.00e+00	705.00
IUUC-Aca-004645	Anolis carolinensis	88.95	0.00e+00	692.00
IUUC-Ame-011401	Astyanax mexicanus	72.56	1.00e-152	532.00
IUUC-Bta-012752	Bos taurus	94.74	0.00e+00	711.00
IUUC-Cja-019734	Callithrix jacchus	95.26	0.00e+00	706.00
IUUC-Cpo-021436	Cavia porcellus	95.26	0.00e+00	730.00
IUUC-Csa-024248	Chlorocebus sabaeus	95.79	0.00e+00	711.00
IUUC-Cho-024528	Choloepus hoffmanni	82.63	5.00e-165	573.00
IUUC-Cin-025748	Ciona intestinalis	29.21	3.00e-22	99.00
IUUC-Csv-025837	Ciona savignyi	35.45	1.00e-67	250.00
IUUC-Dre-027847	Danio rerio	74.02	2.00e-158	551.00
IUUC-Dno-029860	Dasypus novemcinctus	94.21	0.00e+00	697.00
IUUC-Dor-030664	Dipodomys ordii	80.00	5.00e-165	573.00
IUUC-Dse-031509	Dothistroma septosporum	45.10	8.00e-10	59.30
IUUC-Dme-031990	Drosophila melanogaster	31.23	1.00e-37	151.00
IUUC-Ete-032496	Echinops telfairi	70.78	6.00e-113	400.00
IUUC-Eca-033674	Equus caballus	94.27	0.00e+00	751.00
IUUC-Eeu-035048	Erinaceus europaeus	86.05	0.00e+00	659.00
IUUC-Fca-036547	Felis catus	97.11	0.00e+00	768.00
IUUC-Fal-037504	Ficedula albicollis	91.05	0.00e+00	691.00
IUUC-Fox-037905	Fusarium oxysporum	29.49	2.00e-03	35.40
IUUC-Gmo-038660	Gadus morhua	72.73	5.00e-117	414.00
IUUC-Gga-040123	Gallus gallus	91.32	0.00e+00	708.00
IUUC-Gac-042073	Gasterosteus aculeatus	70.23	6.00e-147	513.00
IUUC-Ggo-045387	Gorilla gorilla	95.79	0.00e+00	712.00
IUUC-Hsa-046869	Homo sapiens	95.79	0.00e+00	716.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	95.00	0.00e+00	716.00
IUUC-Lch-049990	Latimeria chalumnae	83.42	0.00e+00	666.00
IUUC-Loc-051908	Lepisosteus oculatus	74.41	8.00e-162	563.00
IUUC-Lma-053223	Leptosphaeria maculans	39.68	4.00e-08	54.70
IUUC-Laf-053915	Loxodonta africana	93.68	0.00e+00	692.00
IUUC-Mcc-054865	Macaca mulatta	95.53	0.00e+00	709.00
IUUC-Meu-056826	Macropus eugenii	99.01	1.00e-54	206.00
IUUC-Mga-059827	Meleagris gallopavo	91.38	0.00e+00	709.00
IUUC-Mmr-060734	Microcebus murinus	96.32	0.00e+00	734.00
IUUC-Mdo-062988	Monodelphis domestica	93.95	0.00e+00	749.00
IUUC-Mmu-064415	Mus musculus	94.74	0.00e+00	669.00
IUUC-Mpu-066118	Mustela putorius furo	98.42	0.00e+00	743.00
IUUC-Mlu-067131	Myotis lucifugus	95.26	0.00e+00	730.00
IUUC-Nle-070112	Nomascus leucogenys	96.05	0.00e+00	710.00
IUUC-Opr-071193	Ochotona princeps	95.26	0.00e+00	706.00
IUUC-Ont-072635	Oreochromis niloticus	70.91	3.00e-149	521.00
IUUC-Oan-073266	Ornithorhynchus anatinus	90.00	0.00e+00	693.00
IUUC-Ocu-074903	Oryctolagus cuniculus	96.32	0.00e+00	737.00
IUUC-Ola-087533	Oryzias latipes	68.63	8.00e-142	496.00
IUUC-Oga-087979	Otolemur garnettii	96.58	0.00e+00	744.00
IUUC-Oar-089747	Ovis aries	94.21	0.00e+00	707.00
IUUC-Ptr-090732	Pan troglodytes	96.05	0.00e+00	713.00
IUUC-Pan-092032	Papio anubis	95.79	0.00e+00	711.00
IUUC-Psi-093296	Pelodiscus sinensis	91.05	0.00e+00	728.00
IUUC-Pma-094351	Petromyzon marinus	52.54	3.00e-33	134.00
IUUC-Pfo-097183	Poecilia formosa	70.74	2.00e-139	489.00
IUUC-Pab-098177	Pongo abelii	95.53	0.00e+00	710.00
IUUC-Pca-100734	Procavia capensis	91.32	0.00e+00	691.00
IUUC-Ppe-101272	Prunus persica	43.10	3.00e-09	56.60
IUUC-Pva-102778	Pteropus vampyrus	96.58	0.00e+00	708.00
IUUC-Rno-106039	Rattus norvegicus	94.47	0.00e+00	701.00
IUUC-Sha-106869	Sarcophilus harrisii	93.68	0.00e+00	746.00
IUUC-Sar-113587	Sorex araneus	62.11	7.00e-129	453.00
IUUC-Ssc-116212	Sus scrofa	95.79	0.00e+00	709.00
IUUC-Tgu-116871	Taeniopygia guttata	91.05	0.00e+00	689.00
IUUC-Tru-117925	Takifugu rubripes	70.76	1.00e-158	553.00
IUUC-Tsy-118815	Tarsius syrichta	94.21	0.00e+00	712.00
IUUC-Tni-120007	Tetraodon nigroviridis	70.98	4.00e-148	517.00
IUUC-Tbe-127381	Tupaia belangeri	92.05	0.00e+00	674.00
IUUC-Ttr-129025	Tursiops truncatus	92.67	1.00e-121	429.00
IUUC-Vpa-130164	Vicugna pacos	76.58	1.00e-155	542.00
IUUC-Xtr-132800	Xenopus tropicalis	82.11	4.00e-180	624.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence