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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-104935
Ensembl Protein ID ENSRNOP00000072673.1
UniProt Accession O35180; O35104; SH3G3_RAT
Genbank Protein ID AAC14884.1; BAA22920.2
Protein Name Endophilin-A3; Endophilin-3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3; SH3p13
Genbank Nucleotide ID AC128742; AB008159
Gene Name Sh3gl3; Sh3d2c1; Sh3p13
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000019776.6 ENSRNOT00000079989.1 ENSRNOP00000072673.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.60e-14 53.9 289 342
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            ++ lyd+e++n++eL +k+Gd++++   ++ de+W +g   l+g +G+fP n+ve +
   Q: 289  CCRGLYDFEPENEGELGFKEGDIITLT--NQIDENWYEG--MLRGESGFFPINYVEVI 342
           5889**********************7..99********..8*************976 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
 Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
Protein Sequence
(Fasta)
MSVAGLKKQF HKASQLFSEK ISGAEGTKLD EEFLDMEKKI DITSKAVAEI LSKATEYLQP 60
NPAYRAKLGM LNTMSKLRGQ VKATGYPQTE GLLGDCMLKY GRELGEDSAF GNSLVEVGEA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-104935|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGCCAGGA GCTAATGGTT CTGGAGAAAT GCTAGAGCCA AAGAGAAGCC CGGATACAGG 60
TGTGAACTGC GAGCGTTGAG GACAACAGTA GTGTTGATGA CCCCTGACCC GACGTTGGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-104935|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR028501--Endophilin-A
IPR032469--Endophilin-A3_BAR
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF07653--SH3_2
PRINTS

PR00452--SH3DOMAIN
SMART

SM00721--BAR
SM00326--SH3
Gene Ontology

GO:0005769--C:early endosome
GO:0031901--C:early endosome membrane
GO:0070062--C:extracellular exosome
GO:0008289--F:lipid binding
GO:0006897--P:endocytosis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001598 Ailuropoda melanoleuca 77.38 6.00e-162 563.00
IUUC-Apl-003422 Anas platyrhynchos 79.59 1.00e-151 528.00
IUUC-Ame-010779 Astyanax mexicanus 69.71 7.00e-155 540.00
IUUC-Bta-012748 Bos taurus 83.05 6.00e-169 586.00
IUUC-Cja-019400 Callithrix jacchus 86.46 4.00e-178 617.00
IUUC-Cfa-020979 Canis familiaris 82.74 4.00e-161 560.00
IUUC-Cpo-021364 Cavia porcellus 84.98 1.00e-165 575.00
IUUC-Csa-023447 Chlorocebus sabaeus 86.46 5.00e-173 599.00
IUUC-Dre-028063 Danio rerio 72.73 3.00e-155 540.00
IUUC-Dno-029219 Dasypus novemcinctus 83.86 3.00e-167 580.00
IUUC-Dme-031633 Drosophila melanogaster 49.46 2.00e-99 355.00
IUUC-Ete-033094 Echinops telfairi 72.51 4.00e-135 473.00
IUUC-Eca-033209 Equus caballus 83.86 3.00e-172 597.00
IUUC-Fca-036354 Felis catus 76.22 6.00e-161 560.00
IUUC-Fal-037519 Ficedula albicollis 78.62 1.00e-140 491.00
IUUC-Gmo-038787 Gadus morhua 69.35 2.00e-141 494.00
IUUC-Gga-041064 Gallus gallus 80.45 9.00e-161 559.00
IUUC-Gac-042091 Gasterosteus aculeatus 72.11 3.00e-146 510.00
IUUC-Hsa-046681 Homo sapiens 85.67 2.00e-164 571.00
IUUC-Itr-048671 Ictidomys tridecemlineatus 85.59 5.00e-176 610.00
IUUC-Lch-050556 Latimeria chalumnae 66.58 8.00e-147 513.00
IUUC-Loc-052711 Lepisosteus oculatus 71.58 5.00e-160 556.00
IUUC-Laf-054427 Loxodonta africana 84.38 2.00e-159 554.00
IUUC-Mcc-055620 Macaca mulatta 85.29 3.00e-165 574.00
IUUC-Mor-056932 Magnaporthe oryzae 36.63 5.00e-13 70.90
IUUC-Mga-059193 Meleagris gallopavo 74.18 7.00e-151 526.00
IUUC-Mmr-060860 Microcebus murinus 73.65 5.00e-136 477.00
IUUC-Mmu-064365 Mus musculus 95.09 0.00e+00 656.00
IUUC-Mpu-066396 Mustela putorius furo 85.88 3.00e-176 610.00
IUUC-Nle-069316 Nomascus leucogenys 85.37 2.00e-169 587.00
IUUC-Opr-070964 Ochotona princeps 82.53 2.00e-160 558.00
IUUC-Ont-071397 Oreochromis niloticus 66.32 4.00e-147 514.00
IUUC-Oar-089220 Ovis aries 85.59 7.00e-168 582.00
IUUC-Ptr-090984 Pan troglodytes 85.67 5.00e-170 590.00
IUUC-Pan-092153 Papio anubis 86.46 5.00e-173 599.00
IUUC-Psi-093559 Pelodiscus sinensis 79.25 5.00e-157 546.00
IUUC-Pab-098780 Pongo abelii 72.59 2.00e-133 468.00
IUUC-Sja-107704 Schizosaccharomyces japonicus 26.24 3.00e-13 69.70
IUUC-Spo-108224 Schizosaccharomyces pombe 26.92 4.00e-24 105.00
IUUC-Tsy-119366 Tarsius syrichta 85.24 6.00e-168 583.00
IUUC-Tbe-127252 Tupaia belangeri 66.99 6.00e-121 427.00
IUUC-Ttr-128272 Tursiops truncatus 76.56 4.00e-140 490.00
Created Date 25-Jun-2017

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