iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012634

Ensembl Protein ID

ENSBTAP00000020709.5

UniProt Accession

F1MIE2; F1MIE2_BOVIN

Genbank Protein ID

ENSBTAP00000020709

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02018966

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000015591.5	ENSBTAT00000020709.5	ENSBTAP00000020709.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.20e-17	63.1	22	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirsfaldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++ a+++++p  +e+Ll++v++ ++ l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAEAEAAPGPRPCERLLNRVAAlFPVLRPGGFQAHYRDEDGDLVAFSSDEELTMAMSY--VKDDIFRIYIKEK 102
           899*****************************999********************************7..9*********975 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MASLTVKAYL LGKEDAAREI RRFSFCFSPE PEAEAEAAPG PRPCERLLNR VAALFPVLRP 60
GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDQR PSCAQEVPRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCAGCTGT GCTCCAGCTC CTCGAGTGGC GGTAATGGCG TCGCTCACGG TGAAGGCCTA 60
CCTTCTGGGC AAGGAGGACG CAGCCCGCGA GATCCGCCGC TTCAGCTTCT GCTTTAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	90.59	4.00e-172	597.00
IUUC-Apl-003897	Anas platyrhynchos	58.91	3.00e-118	418.00
IUUC-Aca-004699	Anolis carolinensis	48.70	8.00e-98	350.00
IUUC-Ame-010982	Astyanax mexicanus	45.07	1.00e-66	247.00
IUUC-Cel-018660	Caenorhabditis elegans	47.73	6.00e-11	60.10
IUUC-Cja-019684	Callithrix jacchus	90.23	0.00e+00	723.00
IUUC-Cfa-020573	Canis familiaris	84.37	1.00e-140	492.00
IUUC-Cpo-021425	Cavia porcellus	78.15	8.00e-178	616.00
IUUC-Csa-023968	Chlorocebus sabaeus	90.68	0.00e+00	716.00
IUUC-Cho-024596	Choloepus hoffmanni	83.23	8.00e-52	197.00
IUUC-Cin-025557	Ciona intestinalis	28.93	7.00e-14	71.20
IUUC-Csv-025974	Ciona savignyi	26.53	3.00e-14	72.40
IUUC-Cne-027045	Cryptococcus neoformans	44.29	1.00e-09	58.90
IUUC-Dre-028621	Danio rerio	44.33	3.00e-97	348.00
IUUC-Dno-029060	Dasypus novemcinctus	86.26	0.00e+00	725.00
IUUC-Dor-030547	Dipodomys ordii	84.62	6.00e-133	467.00
IUUC-Ete-033201	Echinops telfairi	78.55	4.00e-163	566.00
IUUC-Eca-033456	Equus caballus	90.60	0.00e+00	689.00
IUUC-Eeu-035157	Erinaceus europaeus	84.22	3.00e-172	597.00
IUUC-Fca-035403	Felis catus	89.41	0.00e+00	707.00
IUUC-Fal-036798	Ficedula albicollis	58.24	3.00e-135	474.00
IUUC-Gmo-039619	Gadus morhua	41.33	4.00e-48	184.00
IUUC-Gga-040137	Gallus gallus	56.84	1.00e-132	466.00
IUUC-Gac-042410	Gasterosteus aculeatus	46.41	2.00e-101	362.00
IUUC-Ggo-044690	Gorilla gorilla	92.05	0.00e+00	721.00
IUUC-Hsa-046390	Homo sapiens	92.05	0.00e+00	717.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	90.23	0.00e+00	763.00
IUUC-Lch-049658	Latimeria chalumnae	46.81	5.00e-113	400.00
IUUC-Loc-052589	Lepisosteus oculatus	47.71	3.00e-111	395.00
IUUC-Laf-053746	Loxodonta africana	79.73	0.00e+00	636.00
IUUC-Mcc-055635	Macaca mulatta	89.55	0.00e+00	723.00
IUUC-Meu-056528	Macropus eugenii	50.75	5.00e-104	370.00
IUUC-Mga-059458	Meleagris gallopavo	59.05	3.00e-119	421.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	9.00e-08	53.10
IUUC-Mmr-061539	Microcebus murinus	86.12	2.00e-139	488.00
IUUC-Mdo-063083	Monodelphis domestica	63.74	9.00e-151	526.00
IUUC-Mmu-063589	Mus musculus	87.33	0.00e+00	731.00
IUUC-Mpu-065727	Mustela putorius furo	87.87	3.00e-180	624.00
IUUC-Mlu-067026	Myotis lucifugus	87.47	0.00e+00	642.00
IUUC-Nle-069356	Nomascus leucogenys	64.65	2.00e-122	432.00
IUUC-Opr-071091	Ochotona princeps	69.75	1.00e-95	343.00
IUUC-Ont-071864	Oreochromis niloticus	47.38	5.00e-103	367.00
IUUC-Oan-073308	Ornithorhynchus anatinus	62.36	1.00e-134	473.00
IUUC-Ocu-074110	Oryctolagus cuniculus	90.00	0.00e+00	724.00
IUUC-Ola-086944	Oryzias latipes	45.50	4.00e-39	154.00
IUUC-Oga-088869	Otolemur garnettii	89.01	0.00e+00	726.00
IUUC-Oar-089857	Ovis aries	96.80	0.00e+00	694.00
IUUC-Ptr-091640	Pan troglodytes	92.27	0.00e+00	721.00
IUUC-Pan-092831	Papio anubis	90.58	0.00e+00	714.00
IUUC-Psi-093925	Pelodiscus sinensis	55.65	9.00e-126	443.00
IUUC-Pma-094576	Petromyzon marinus	31.29	7.00e-31	128.00
IUUC-Pfo-097297	Poecilia formosa	44.88	1.00e-92	333.00
IUUC-Pab-098725	Pongo abelii	81.82	0.00e+00	632.00
IUUC-Pca-101106	Procavia capensis	89.32	0.00e+00	697.00
IUUC-Pva-102710	Pteropus vampyrus	86.67	0.00e+00	645.00
IUUC-Rno-105539	Rattus norvegicus	88.46	0.00e+00	743.00
IUUC-Sha-107469	Sarcophilus harrisii	60.00	3.00e-124	438.00
IUUC-Ssc-115526	Sus scrofa	93.64	0.00e+00	749.00
IUUC-Tgu-117194	Taeniopygia guttata	61.24	9.00e-121	426.00
IUUC-Tru-117896	Takifugu rubripes	47.53	2.00e-101	362.00
IUUC-Tni-119943	Tetraodon nigroviridis	48.19	2.00e-92	332.00
IUUC-Ttr-128676	Tursiops truncatus	93.41	0.00e+00	778.00
IUUC-Vda-129812	Verticillium dahliae	44.64	2.00e-07	51.20
IUUC-Vpa-130319	Vicugna pacos	95.00	9.00e-56	210.00
IUUC-Xtr-132907	Xenopus tropicalis	53.59	2.00e-126	445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence